Development of a direct contact astrocyte-human cerebral microvessel endothelial cells blood-brain barrier coculture model

Transporter-Based Delivery of Anticancer Drugs to the Brain: Improving Brain Penetration by Minimizing Drug Efflux at the Blood-Brain Barrier

(2014) Ngoc On et al.   CURRENT PHARMACEUTICAL DESIGN

A retinoic acid-enhanced, multicellular human blood-brain barrier model derived from stem cell sources

(2014) Ethan S. Lippmann et al.   Scientific Reports

Blood–brain barrier structure and function and the challenges for CNS drug delivery

(2013) N. Joan Abbott   JOURNAL OF INHERITED METABOLIC DISEASE

Wnt Activation of Immortalized Brain Endothelial Cells as a Tool for Generating a Standardized Model of the Blood Brain Barrier In Vitro

(2013) Roberta Paolinelli et al.   PLoS One

The effects of intralaboratory modifications to media composition and cell source on the expression of pharmaceutically relevant transporters and metabolizing genes in the Caco‐2 cell line

(2012) Wyatt J. Roth et al.   JOURNAL OF PHARMACEUTICAL SCIENCES

Derivation of blood-brain barrier endothelial cells from human pluripotent stem cells

(2012) Ethan S Lippmann et al.   NATURE BIOTECHNOLOGY

Transcriptional Profiling of Human Brain Endothelial Cells Reveals Key Properties Crucial for Predictive In Vitro Blood-Brain Barrier Models

(2012) Eduard Urich et al.   PLoS One

Development of a three-dimensional, all-human in vitro model of the blood–brain barrier using mono-, co-, and tri-cultivation Transwell models

(2011) Kathryn Hatherell et al.   JOURNAL OF NEUROSCIENCE METHODS

The Effects of Media on Pharmaceutically Relevant Transporters in the Human HT-29 Adenocarcinoma Cell Line: Does Culture Media Need to be Controlled?

(2011) David J. Lindley et al.   JOURNAL OF PHARMACEUTICAL SCIENCES

Paracellular Tightness and Claudin-5 Expression is Increased in the BCEC/Astrocyte Blood–Brain Barrier Model by Increasing Media Buffer Capacity During Growth

(2010) Hans Christian Helms et al.   AAPS Journal

Permeability of Endothelial and Astrocyte Cocultures: In Vitro Blood–Brain Barrier Models for Drug Delivery Studies

(2010) Guanglei Li et al.   ANNALS OF BIOMEDICAL ENGINEERING

Metabolic Acidosis Induced by Plasmodium Falciparum Intraerythrocytic Stages Alters Blood—Brain Barrier Integrity

(2010) Sergine Zougbédé et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Effect of HEPES Buffer on the Uptake and Transport of P-Glycoprotein Substrates and Large Neutral Amino Acids

(2010) Shuanghui Luo et al.   MOLECULAR PHARMACEUTICS

ABC and SLC Transporter Expression and Pot Substrate Characterization across the Human CMEC/D3 Blood−Brain Barrier Cell Line

(2010) Stephen M. Carl et al.   MOLECULAR PHARMACEUTICS

Polarized P-glycoprotein expression by the immortalised human brain endothelial cell line, hCMEC/D3, restricts apical-to-basolateral permeability to rhodamine 123

(2009) Leon M. Tai et al.   BRAIN RESEARCH

Closing the gap between the in-vivo and in-vitro blood–brain barrier tightness

(2009) Katayun Cohen-Kashi Malina et al.   BRAIN RESEARCH

Immortalized Human Brain Endothelial Cell Line HCMEC/D3 as a Model of the Blood-Brain Barrier Facilitates In Vitro Studies of Central Nervous System Infection byCryptococcus neoformans

(2009) Kiem Vu et al.   EUKARYOTIC CELL

The human brain endothelial cell line hCMEC/D3 as a human blood-brain barrier model for drug transport studies

(2008) Birk Poller et al.   JOURNAL OF NEUROCHEMISTRY

Differential effects of hydrocortisone and TNFα on tight junction proteins in anin vitromodel of the human blood-brain barrier

(2008) Carola Förster et al.   JOURNAL OF PHYSIOLOGY-LONDON