Adenoma development in familial adenomatous polyposis andMUTYH-associated polyposis: somatic landscape and driver genes

Replicative DNA polymerase mutations in cancer

(2014) Ellen Heitzer et al.   CURRENT OPINION IN GENETICS & DEVELOPMENT

Genetic instability in lymphoblastoid cell lines expressing biallelic and monoallelic variants in the human MUTYH gene

(2014) Francesca Grasso et al.   HUMAN MOLECULAR GENETICS

Recurrent PTPRB and PLCG1 mutations in angiosarcoma

(2014) Sam Behjati et al.   NATURE GENETICS

Cake: a bioinformatics pipeline for the integrated analysis of somatic variants in cancer genomes

(2013) Mamunur Rashid et al.   BIOINFORMATICS

Signatures of mutational processes in human cancer

(2013) Ludmil B. Alexandrov et al.   NATURE

EMu: probabilistic inference of mutational processes and their localization in the cancer genome

(2013) Andrej Fischer et al.   GENOME BIOLOGY

A Single-Nucleotide Substitution Mutator Phenotype Revealed by Exome Sequencing of Human Colon Adenomas

(2012) S. I. Nikolaev et al.   CANCER RESEARCH

Prevalence and Phenotypes of APC and MUTYH Mutations in Patients With Multiple Colorectal Adenomas

(2012) Shilpa Grover et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

The WTX Tumor Suppressor Enhances p53 Acetylation by CBP/p300

(2012) Woo Jae Kim et al.   MOLECULAR CELL

Comprehensive molecular characterization of human colon and rectal cancer

(2012)   NATURE

Germline mutations affecting the proofreading domains of POLE and POLD1 predispose to colorectal adenomas and carcinomas

(2012) Claire Palles et al.   NATURE GENETICS

The WTX Tumor Suppressor Regulates Mesenchymal Progenitor Cell Fate Specification

(2011) Annie Moisan et al.   DEVELOPMENTAL CELL

The GENCODE exome: sequencing the complete human exome

(2011) Alison J Coffey et al.   EUROPEAN JOURNAL OF HUMAN GENETICS

Evidence for accelerated colorectal adenoma–carcinoma progression inMUTYH-associated polyposis?

(2011) M H Nieuwenhuis et al.   GUT

Somatic Mutation Profiles of MSI and MSS Colorectal Cancer Identified by Whole Exome Next Generation Sequencing and Bioinformatics Analysis

(2010) Bernd Timmermann et al.   PLoS One

The tumor suppressor WTX shuttles to the nucleus and modulates WT1 activity

(2009) M. N. Rivera et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Germline mutations in WTX cause a sclerosing skeletal dysplasia but do not predispose to tumorigenesis

(2008) Zandra A Jenkins et al.   NATURE GENETICS

APC and the three-hit hypothesis

(2008) S Segditsas et al.   ONCOGENE