The anticancer drug sunitinib promotes autophagyand protects from neurotoxicity in an HIV-1 Tat model of neurodegeneration

Mitochondrial injury and cognitive function in HIV infection and methamphetamine use

(2016) Susanna R. Var et al.   AIDS

HIV alters neuronal mitochondrial fission/fusion in the brain during HIV-associated neurocognitive disorders

(2016) Jerel Adam Fields et al.   NEUROBIOLOGY OF DISEASE

Loss of endophilin-B1 exacerbates Alzheimer’s disease pathology

(2015) David B. Wang et al.   BRAIN

Impaired neurogenesis by HIV-1-Gp120 is rescued by genetic deletion of fatty acid amide hydrolase enzyme

(2015) H K Avraham et al.   BRITISH JOURNAL OF PHARMACOLOGY

Mechanisms of HIV-1 Tat Neurotoxicity via CDK5 Translocation and Hyper-Activation: Role in HIV-Associated Neurocognitive Disorders

(2015) Jerel Fields et al.   CURRENT HIV RESEARCH

HIV-1 Tat Alters Neuronal Autophagy by Modulating Autophagosome Fusion to the Lysosome: Implications for HIV-Associated Neurocognitive Disorders

(2015) J. Fields et al.   JOURNAL OF NEUROSCIENCE

Decreased neuronal autophagy in HIV dementia: A mechanism of indirect neurotoxicity

(2014) Mehrdad Alirezaei et al.   Autophagy

Neuroprotective effects of the anti-cancer drug sunitinib in models of HIV neurotoxicity suggests potential for the treatment of neurodegenerative disorders

(2014) Wolf Wrasidlo et al.   BRITISH JOURNAL OF PHARMACOLOGY

HIV-1 Tat protein induces glial cell autophagy through enhancement of BAG3 protein levels

(2014) Anna Paola Bruno et al.   CELL CYCLE

Cdk5 activity in the brain - multiple paths of regulation

(2014) K. Shah et al.   JOURNAL OF CELL SCIENCE

Bax Interacting Factor-1 Promotes Survival and Mitochondrial Elongation in Neurons

(2014) D. B. Wang et al.   JOURNAL OF NEUROSCIENCE

Hippocampal neuronal cells that accumulate α-synuclein fragments are more vulnerable to Aβ oligomer toxicity via mGluR5 – implications for dementia with Lewy bodies

(2014) Cassia R Overk et al.   Molecular Neurodegeneration

Pazopanib and sunitinib trigger autophagic and non-autophagic death of bladder tumour cells

(2013) M Santoni et al.   BRITISH JOURNAL OF CANCER

Alterations in the Levels of Vesicular Trafficking Proteins Involved in HIV Replication in the Brains and CSF of Patients with HIV-associated Neurocognitive Disorders

(2013) Jerel Fields et al.   Journal of Neuroimmune Pharmacology

Impaired neurogenesis and neurite outgrowth in an HIV-gp120 transgenic model is reversed by exercise via BDNF production and Cdk5 regulation

(2013) Myoung-Hwa Lee et al.   JOURNAL OF NEUROVIROLOGY

Detection of anti-tat antibodies in CSF of individuals with HIV-associated neurocognitive disorders

(2013) M. Bachani et al.   JOURNAL OF NEUROVIROLOGY

Age-dependent molecular alterations in the autophagy pathway in HIVE patients and in a gp120 tg mouse model: reversal with beclin-1 gene transfer

(2013) Jerel Fields et al.   JOURNAL OF NEUROVIROLOGY

HIV-associated neurocognitive disorder

(2013) David B Clifford et al.   LANCET INFECTIOUS DISEASES

Viral protein R upregulates expression of ULBP2 on uninfected bystander cells during HIV-1 infection of primary CD4+ T lymphocytes

(2013) Jonathan Richard et al.   VIROLOGY

The many faces of α-synuclein: from structure and toxicity to therapeutic target

(2012) Hilal A. Lashuel et al.   NATURE REVIEWS NEUROSCIENCE

Autophagic activation potentiates the antiproliferative effects of tyrosine kinase inhibitors in medullary thyroid cancer

(2012) Chi-Iou Lin et al.   SURGERY

HIV-1 Tat binds to SH3 domains: Cellular and viral outcome of Tat/Grb2 interaction

(2011) Slava Rom et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Autophagy Is Increased in Postmortem Brains of Persons With HIV-1-Associated Encephalitis

(2011) Dejiang Zhou et al.   JOURNAL OF INFECTIOUS DISEASES

Cdk5-mediated phosphorylation of endophilin B1 is required for induced autophagy in models of Parkinson's disease

(2011) Alan S. L. Wong et al.   NATURE CELL BIOLOGY

A soluble  -synuclein construct forms a dynamic tetramer

(2011) W. Wang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Does highly active antiretroviral therapy improve neurocognitive function? A systematic review

(2010) John A Joska et al.   JOURNAL OF NEUROVIROLOGY

HIV-associated neurocognitive disorders before and during the era of combination antiretroviral therapy: differences in rates, nature, and predictors

(2010) Robert K. Heaton et al.   JOURNAL OF NEUROVIROLOGY

Depletion of Beclin-1 due to proteolytic cleavage by caspases in the Alzheimer's disease brain

(2010) Troy T. Rohn et al.   NEUROBIOLOGY OF DISEASE

HIV-associated neurocognitive disorders persist in the era of potent antiretroviral therapy: CHARTER Study

(2010) R. K. Heaton et al.   NEUROLOGY

Selective Molecular Alterations in the Autophagy Pathway in Patients with Lewy Body Disease and in Models of α-Synucleinopathy

(2010) Leslie Crews et al.   PLoS One

Anti-angiogenic tyrosine kinase inhibitors: what is their mechanism of action?

(2009) Kristy J. Gotink et al.   ANGIOGENESIS

Bif-1/Endophilin B1: a candidate for crescent driving force in autophagy

(2009) Y Takahashi et al.   CELL DEATH AND DIFFERENTIATION

Autophagy pathway intersects with HIV-1 biosynthesis and regulates viral yields in macrophages

(2009) George B. Kyei et al.   JOURNAL OF CELL BIOLOGY

Increased Accumulation of Intraneuronal Amyloid β in HIV-Infected Patients

(2009) Cristian L. Achim et al.   Journal of Neuroimmune Pharmacology

Beclin 1 Gene Transfer Activates Autophagy and Ameliorates the Neurodegenerative Pathology in  -Synuclein Models of Parkinson's and Lewy Body Diseases

(2009) B. Spencer et al.   JOURNAL OF NEUROSCIENCE

Disruption of Neuronal Autophagy by Infected Microglia Results in Neurodegeneration

(2008) Mehrdad Alirezaei et al.   PLoS One

HIV-1 Tat Activates Neuronal Ryanodine Receptors with Rapid Induction of the Unfolded Protein Response and Mitochondrial Hyperpolarization

(2008) John P. Norman et al.   PLoS One