Report of effective trametinib therapy in 2 children with progressive hypothalamic optic pathway pilocytic astrocytoma: documentation of volumetric response

Pilocytic astrocytoma: pathology, molecular mechanisms and markers

(2015) V. Peter Collins et al.   ACTA NEUROPATHOLOGICA

Current Understanding of BRAF Alterations in Diagnosis, Prognosis, and Therapeutic Targeting in Pediatric Low-Grade Gliomas

(2015) Catherine Louise Penman et al.   Frontiers in Oncology

Ras/Raf/MEK/ERK and PI3K/PTEN/Akt/mTOR Cascade Inhibitors: How Mutations Can Result in Therapy Resistance and How to Overcome Resistance

(2015) James Andrew McCubrey et al.   Oncotarget

Chromosome Band 7q34 Deletions Resulting inKIAA1549-BRAFandFAM131B-BRAFFusions in Pediatric Low-Grade Gliomas

(2014) Jacquelyn J. Roth et al.   BRAIN PATHOLOGY

Phase II study of sorafenib in children with recurrent or progressive low-grade astrocytomas

(2014) M. A. Karajannis et al.   NEURO-ONCOLOGY

The molecular and cell biology of pediatric low-grade gliomas

(2013) Y-H Chen et al.   ONCOGENE

Analysis of BRAF V600E mutation in 1,320 nervous system tumors reveals high mutation frequencies in pleomorphic xanthoastrocytoma, ganglioglioma and extra-cerebellar pilocytic astrocytoma

(2011) Genevieve Schindler et al.   ACTA NEUROPATHOLOGICA

MAPK pathway activation in pilocytic astrocytoma

(2011) David T. W. Jones et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Duplication of 7q34 is specific to juvenile pilocytic astrocytomas and a hallmark of cerebellar and optic pathway tumours

(2009) K Jacob et al.   BRITISH JOURNAL OF CANCER