Article
Engineering, Electrical & Electronic
Youluan Lu, Xinwei Mu, Yaopeng Liu, Zhen Shi, Yin Zheng, Wensheng Huang, Fangming Lou
Summary: Salt molecules were introduced into lotus root through bioconcentration, and a porous carbon material with 3D pore structure was prepared based on the lotus root. The material was characterized and its electrochemical performance as a sensor was examined. The sensor exhibited good performance in Chinese herbal medicine and healthy human urine samples.
JOURNAL OF MATERIALS SCIENCE-MATERIALS IN ELECTRONICS
(2022)
Article
Biochemistry & Molecular Biology
Emilia P. T. Leitao, Osvaldo S. Ascenso, Tania Santos de Almeida, Ignacio Gonzalez, Inmaculada Hernandez, Jose Quintana, Francisco Estevez, Patricia Rijo
Summary: A series of hydroxylated chalcone derivatives with different substitution patterns were prepared, and it was found that the naphthylchalcone containing a methoxy group in position 6 ' of the A ring exhibited the highest cytotoxicity against human leukaemia cells.
BIOORGANIC CHEMISTRY
(2021)
Article
Food Science & Technology
Chandrakant Ankolekar, Dipayan Sarkar, Duane Greene, Kalidas Shetty
Summary: The studies demonstrate that the use of bioprocessed food-grade elicitors such as OX and COS can be recruited as a novel tool to enhance protective phenolic responses for improving the quality of apples targeted for managing type 2 diabetes and post-harvest storage quality.
FRONTIERS IN SUSTAINABLE FOOD SYSTEMS
(2021)
Article
Chemistry, Applied
Carlos Arthur G. Veloso, Indyra Alencar D. Figueiredo, Gleice Rayanne da Silva, Jose Iranildo Miranda de Melo, Marcelo S. da Silva, Josean F. Tavares, Fabiana de A. Cavalcante, Vicente Carlos de O. Costa
Summary: Pharmacological studies on Varronia dardani leaves extract showed non-selective spasmolytic activity in various tissues, with flavonoids identified as potential bioactive compounds responsible for this activity.
NATURAL PRODUCT RESEARCH
(2021)
Article
Chemistry, Applied
Gustavo Ruivo Salmazzo, Maria Helena Verdan, Flavia Silva, Regina Maria Cicarelli, Jonas da Silva Mota, Marcos Jose Salvador, Joao Ernesto de Carvalho, Claudia Andrea Lima Cardoso
Summary: Chemical investigation of Campomanesia xanthocarpa fruit extracts led to the isolation of six known compounds, showing significant antioxidant capacity and promising anti-cancer activity against various cancer cell lines. The compounds also demonstrated improved trypanocidal activity against Trypanosoma cruzi.
NATURAL PRODUCT RESEARCH
(2021)
Article
Chemistry, Applied
Yuan Chen, Heli Pan, Shuxia Hao, Dongming Pan, Guojun Wang, Wenquan Yu
Summary: This study evaluated phenolic compounds and antioxidant activities in the peels of 52 citrus varieties. Mandarin had the highest levels of total phenols and total flavonoids, while kumquat had the highest phenolic acid content. The antioxidant potency composite index suggested certain mandarin varieties had the highest antioxidant activity, and statistical analysis showed a positive correlation between phenolic compounds and antioxidant activity.
Review
Biochemistry & Molecular Biology
Leonardo O. Aguiar, Eliane de Oliveira Silva, Jorge M. David
Summary: Chalcones and flavanones are important secondary metabolites in plants that can be obtained as new derivatives through biotransformation methods, with wide potential applications.
BIOCATALYSIS AND BIOTRANSFORMATION
(2022)
Article
Chemistry, Multidisciplinary
Shaik Ammaji, Shaik Masthanamma, Richie R. Bhandare, Sivakumar Annadurai, Afzal Basha Shaik
Summary: A series of chalcone analogues were synthesized and characterized, showing potential as new antitubercular and antioxidant agents. The compounds exhibited strong inhibitory effects against isocitrate lyase and promising drug likeliness properties.
ARABIAN JOURNAL OF CHEMISTRY
(2022)
Article
Chemistry, Multidisciplinary
Ashmita Singh, Anudeep Kumar Narula
Summary: A new methodology was developed for the synthesis of substituted, bicyclic 3-benzoyl flavanone derivatives by [4+2] annulations of salicylaldehyde with chalcones using N-heterocyclic carbene (NHC) as a catalyst, I-2 as co-catalyst and tert-butyl hydroperoxide (TBHP) as an oxidant in ethanol. The methodology was effective across a range of electron-deficient to electron-rich substrates.
Article
Biochemistry & Molecular Biology
Andromachi Tzani, Eftichia Kritsi, Lamprini Tsamantioti, Ioanna Kostopoulou, Maria-Anna Karadendrou, Panagiotis Zoumpoulakis, Anastasia Detsi
Summary: Flavanones and their biochemical precursors, chalcones, are naturally occurring compounds that are used in drug discovery for their diverse range of biological activities. In this study, novel flavanones and chalcones were synthesized and their antioxidant activity and DNA-binding ability were evaluated. The results showed that arylidene flavanone 5 exhibited the highest antioxidant activity, while chalcone 6 had the strongest interaction with DNA.
Article
Pharmacology & Pharmacy
Temitope Isaac Adelusi, Gbemisola Rebecca Akinbolaji, Xiaoxing Yin, Kehinde Sulaimon Ayinde, Olamide Tosin Olaoba
Summary: Neurological diseases resulting from CNS injury raise societal concerns, with current therapeutic strategies facing challenges. Emerging studies show the neuroprotective potential of natural compounds, such as chalcones, in safeguarding CNS structures.
EUROPEAN JOURNAL OF PHARMACOLOGY
(2021)
Article
Multidisciplinary Sciences
Jalal Uddin, Syed Wadood Ali Shah, Muhammad Zahoor, Riaz Ullah, Amal Alotaibi
Summary: In this study, chalcones were synthesized and characterized, and their antioxidant and antidiabetic potential were evaluated. The results showed that JA3 exhibited high antioxidant and antidiabetic activity, demonstrating significant therapeutic efficacy in the animal model.
Article
Nutrition & Dietetics
Jolita Stabrauskiene, Mindaugas Marksa, Liudas Ivanauskas, Pranas Viskelis, Jonas Viskelis, Jurga Bernatoniene
Summary: Citrus fruits, especially grapefruit, have been extensively studied for their antioxidant properties and potential health benefits in preventing and treating chronic diseases. A novel method using cyclodextrin complexes has been developed to increase the extraction yield of flavanones from grapefruit. This method improves the efficiency and cost-effectiveness of the extraction process, resulting in higher yields of beneficial compounds.
Article
Chemistry, Physical
Changjiao Shang, Yajie Zhang, Chaofan Sun, Lingling Wang
Summary: In this study, the substituent and solvent effects on the antioxidant activity of 2'-hydroxychalcone were investigated in different phases. The results provide guidance for synthesizing high-efficiency antioxidants and explore potential application fields for 2'Cha.
JOURNAL OF MOLECULAR LIQUIDS
(2022)
Review
Biochemistry & Molecular Biology
Fabiola De Luca, Carla Di Chio, Maria Zappala, Roberta Ettari
Summary: Dihydrochalcones are a class of secondary metabolites with various biological properties, making them promising candidates in the drug discovery process. This review discusses their pharmacological actions, focusing on their antitumor activity against cancer cell lines and the mechanisms underlying cell proliferation inhibition.
CURRENT MEDICINAL CHEMISTRY
(2022)
Article
Energy & Fuels
Habib Ullah, Zakir Ullah, Zafar A. K. Khattak, Mohsin Ali Marwat, Baoyi Yu, Hyung Wook Kwon, Hyun You Kim, Francis Verpoort
Summary: Transforming atmospheric CO2 into industrially valuable cyclic carbonates is important for reducing CO2 concentration. Ruthenium catalysts with ONN pincer-type hydrazone ligands were synthesized and tested for CO2 valorization. These complexes showed improved catalytic performance, with a high turnover frequency of 833 h^-1 and >99% selectivity at atmospheric pressure without any cocatalyst.
Article
Energy & Fuels
Pongpon Teerachawanwong, Waralee Dilokekunakul, Poomiwat Phadungbut, Nikom Klomkliang, Somsak Supasitmongkol, Somboon Chaemchuen, Francis Verpoort
Summary: Metal-organic frameworks (MOFs) MIL-100 (Cr, Fe) synthesized by the hydrothermal method were subjected to heat treatment under an H(2 )flow, which enhanced crystallinity and exhibited superior CO2 adsorption capacity. The adsorption mechanism at a molecular level was examined using the grand canonical Monte Carlo method, and the heat contribution of each atom type was determined.
Article
Chemistry, Physical
Salma Aman, Naseeb Ahmad, Sumaira Manzoor, Meznah M. Alanazi, Shaimaa A. M. Abdelmohsen, Rabia Yasmin Khosa, Abdullah G. Al-Sehemi, Ruimao Hua, Huda A. Alzahrani, Adeel Hussain Chughtai
Summary: A simple and basic procedure was applied to fabricate Cu-substituted ZnMn2O4/rGO spinel nanosized composite, which showed excellent electrocatalytic efficiency for OER. The composite exhibited low overpotential, low onset potential, small Tafel slope, high electrochemical surface area, electron transfer coefficient and exceptional stability, making it a promising material for energy generation and other fields.
CATALYSIS SURVEYS FROM ASIA
(2023)
Article
Materials Science, Ceramics
Muhammad Zeshan, Mahmood Ali, Meznah M. Alanazi, ShaimaaA. M. Abdelmohsen, Rabia Yasmin Khosa, Abdullah G. Al-Sehemi, Mohd Zahid Ansari, Roaa A. Tayeb, Hafiz Muhammad Tahir Farid, Mohammed M. Rahman
Summary: High-frequency nanocomposites, consisting of ferrite and a polyaniline matrix, have become the focus of electronic and telecommunication technologies. The addition of spinel ferrite to the nanocomposites through sol-gel technique and in-situ synthesis improved their crystallite size and reduced the dielectric constants and dielectric loss. The composite materials also exhibited ferromagnetic characteristics and enhanced resistivity and activation energies.
CERAMICS INTERNATIONAL
(2023)
Article
Engineering, Electrical & Electronic
K. S. Ramesh, Saravanabhavan Munusamy, Shabbir Muhammad, Mari Sithambaram Karthikeyan, Abdullah G. Al-Sehemi, M. Sekar
Summary: This study investigates the nonlinear optical properties of single-crystal 2-amino-6-ethoxy benzothiazolium diphenylacetate (BTDPA). Thermal and characterization studies, including spectroscopy and NLO measurements, were conducted on BTDPA crystal. Quantum chemical calculations were performed to optimize the molecular geometry and determine the electronic charge distributions and transitions. The results demonstrate that BTDPA exhibits good optical and nonlinear optical properties, making it valuable for optoelectronic and laser applications.
JOURNAL OF MATERIALS SCIENCE-MATERIALS IN ELECTRONICS
(2023)
Article
Engineering, Electrical & Electronic
F. F. Alharbi, Syeda Rabia Ejaz, Abdullah G. G. Al-Sehemi, Muhammad Suleman Waheed, Muhammd Noman Saeed, Hafiz Muhammad Tahir Farid
Summary: The release of noxious organic pollutant from the textile industry poses a severe hazard to living organisms and aquatic components. While the aluminate spinel family serves as a potent photocatalyst for mineralizing organic dyes under visible light, their efficiency can be improved by composite strategies with carbon-based materials. In this study, a CoAl2O4/rGO nanocomposite was synthesized using the hydrothermal method and characterized using various analytical tools. The nanocomposite exhibited a significantly higher photocatalytic efficiency of 97.16% compared to CoAl2O4 (77.51%) and rGO (88.01%). The enhanced photomineralization is attributed to the reduced electron-hole recombination and the large interfacial area of the rGO nanosheet.
JOURNAL OF MATERIALS SCIENCE-MATERIALS IN ELECTRONICS
(2023)
Article
Chemistry, Physical
M. Vimala, S. Stella Mary, Ahmad Irfan, S. Muthu
Summary: Vibrational analysis and skeletal parameter were calculated using the B3LYP method. The stabilization energy of 2PYP was computed. The charge excitation, hole-electron distribution, and overlap were studied using multiwfn software. Electron localization function, localized orbital locator, and thermodynamical analysis were performed to determine the electron density and thermodynamic functions (entropy, enthalpy, and specific heat capacity) of 2PYP. NLO parameters, MESP, UV-vis analysis, and HOMO-LUMO analysis were conducted in non-polar, polar aprotic, and polar protic solvents.
JOURNAL OF MOLECULAR LIQUIDS
(2023)
Article
Biotechnology & Applied Microbiology
Zhi Chen, Chenshuo Wu, Yuxuan Yuan, Zhongjian Xie, Tianzhong Li, Hao Huang, Shuang Li, Jiefeng Deng, Huiling Lin, Zhe Shi, Chaozhou Li, Yabin Hao, Yuxuan Tang, Yuehua You, Omar A. Al-Hartomy, Swelm Wageh, Abdullah G. Al-Sehemi, Ruitao Lu, Ling Zhang, Xuechun Lin, Yaqing He, Guojun Zhao, Defa Li, Han Zhang
Summary: Since the end of 2019, a highly contagious disease called COVID-19, caused by SARS-CoV-2, has claimed numerous lives worldwide. The latest variant of concern is omicron, and BA.5 is becoming the dominant subtype, replacing the BA.2 variant. These subtypes have an L452R mutation, which increases their transmissibility among vaccinated individuals. Current methods for identifying SARS-CoV-2 variants rely on time-consuming and costly PCR-based gene sequencing. In this study, researchers developed a rapid and ultrasensitive electrochemical biosensor using MXene-AuNP electrodes and the CRISPR/Cas13a system to detect the L452R mutation in RNA samples, enabling early diagnosis and distinguishing omicron BA.5 and BA.2 variants.
JOURNAL OF NANOBIOTECHNOLOGY
(2023)
Article
Chemistry, Analytical
Abdullah Al-Sehemi, Ahmed Al-Ghamdi, Nikolay Dishovsky, Nikolay Atanasov, Gabriela Atanasova
Summary: A flexible miniature antenna for body-worn devices has been developed to ensure flexibility and comfort when in contact with the human body. Using the quadratic Koch curve, the antenna achieved a maximum telemetry range of over 80 mm for in-body communications and over 2 m for off-body communications. With its compact dimensions and low manufacturing price, the proposed antenna is an ideal candidate for health telemetry applications.
Article
Environmental Sciences
Sathishkumar Munusamy, Triveni Rajashekhar Mandlimath, Puchakayala Swetha, Abdullah G. Al-Sehemi, Mehboobali Pannipara, Sivasankar Koppala, Paramasivam Shanmugam, Supakorn Boonyuen, Ramyakrishna Pothu, Rajender Boddula
Summary: Doped carbon dots with nitrogen have attracted great attention due to their unique characteristics and have been widely explored in various applications. This article reviews the recent breakthroughs in nitrogen-doped carbon dots for fluorescent sensor applications, including synthetic methods, fluorescent features, sensing mechanisms, and sensor applications for various targets. The potential future directions of nitrogen-doped carbon dots in primary research are also discussed.
ENVIRONMENTAL RESEARCH
(2023)
Article
Chemistry, Physical
S. Selvakumari, Krishna Murthy Potla, D. Shanthi, Ahmad Irfan, S. Muthu
Summary: In this study, the aromatic molecule imidazo[1,2-a]pyridine-8-carboxylic acid was examined using the DFT approach. The solvation effects, structural characterization, and biological characteristics of the molecule were discussed. Computational methods such as NBO and NLO were used to determine its stability and optical properties, and molecular docking studies suggested its potential as an anti-inflammatory drug.
JOURNAL OF MOLECULAR LIQUIDS
(2023)
Correction
Chemistry, Multidisciplinary
Gunasekaran Arunkumar, Periyappan Nantheeswaran, Mariappan Mariappan, Ravi Kanth Kamlekar, Mehboobali Pannipara, Abdullah G. G. Al-Sehemi, Savarimuthu Philip Anthony
Summary: The paper introduces a study on cobalt metal-organic framework microcrystalline particles with strong electrocatalytic activity, achieved by amine-controlled morphology and OER activity.
NEW JOURNAL OF CHEMISTRY
(2023)
Article
Chemistry, Multidisciplinary
Gunasekaran Arunkumar, Periyappan Nantheeswaran, Mariappan Mariappan, Ravi Kanth Kamlekar, Mehboobali Pannipara, Abdullah G. Al-Sehemi, Savarimuthu Philip Anthony
Summary: Metal organic framework (MOF) based electrocatalysts, such as cobalt-terephthalic acid (CoTPA) MOFs, have been widely studied due to their customizable structure, functionality, and porosity. In this work, microcrystalline CoTPA MOFs particles were synthesized with different organic amines, leading to variations in morphology, surface area, and pore diameter. XPS analysis revealed the presence of Co2+ and Co3+ in the MOFs, and all four MOFs demonstrated excellent electrocatalytic oxygen evolution reaction (OER) activity in alkaline medium. Notably, CoTPA-D exhibited the highest OER activity, attributed to its faster reaction kinetics and availability of more active sites. Post-catalytic analysis indicated the conversion of CoMOFs into CoOOH during electrocatalysis, resulting in enhanced OER reaction. The findings of this study highlight the importance of structure design and functionality control in MOF-based electrocatalysts.
NEW JOURNAL OF CHEMISTRY
(2023)
Article
Chemistry, Multidisciplinary
Pandi Muthukumar, Gunasekaran Arunkumar, Mehboobali Pannipara, Abdullah G. Al-Sehemi, Dohyun Moon, Savarimuthu Philip Anthony
Summary: In this study, copper complexes with different structures were synthesized and their oxygen evolution reaction (OER) activity in alkaline medium was investigated. It was found that the bimetallic copper complex CuPz-H2O center dot H2O with lattice water and shorter intermetallic spacing showed strong OER activity. The bimetallic copper complex CuPz-H2O without lattice water and the bimetallic complex CuBipy-H2O center dot H2O with increased intermetallic spacing exhibited relatively lower OER activity. These findings provide insights for designing efficient electrocatalysts based on metal coordination compounds.
Article
Energy & Fuels
Somboon Chaemchuen, Zhonghan Cheng, Xiaotong Hou, Francis Verpoort, Jakkapan Kumsi, Nikom Klomkliang
Summary: This paper presents a synthesis method for bimetallic nickel/zinc embedded in N-doped carbon through solid-solid thermal method. The resulting material exhibits a robust carbon structure and shows efficient CO2 adsorption potential compared to commercial activated charcoal.
Article
Chemistry, Physical
Xinlei Chen, Shiyi Chen, Xuele Lin, Jingxuan Zhou, Xingjun Gao, Yaoqi Zhen, Xiaodan Ma, Shouwen Jin, Linfang Shi, Hui Liu, Daqi Wang
Summary: Nine mixed-ligand Cd2+ complexes with different geometric structures were synthesized and characterized. The complexes exhibit various coordination modes and form both intra- and intermolecular hydrogen bonds.
JOURNAL OF MOLECULAR STRUCTURE
(2024)
Article
Chemistry, Physical
Rupali Mahajan, Abhishek Sharma, Bhagyashree Patra, Lijo Mani, Parul Grover, Sandeep Kumar, Santosh Kumar Guru, Gananadhamu Samanthula, Amol G. Dikundwar, Amit Asthana
Summary: This research article provides a comprehensive characterization and toxicological assessment of a photoisomeric impurity of the antianemic drug Roxadustat. The impurity has a distinct structure compared to the drug and its formation due to light exposure is a concern. Through various experiments, including single crystal XRD, physicochemical characterization, and in vitro cytotoxicity assays, the researchers confirmed the structure of the impurity, evaluated its conversion with Roxadustat, and assessed its toxicological activity. These findings contribute to the understanding of drug stability, safety, and formulation development.
JOURNAL OF MOLECULAR STRUCTURE
(2024)
Article
Chemistry, Physical
Laila S. Alqarni, Azzah M. Alghamdi, Nuha Y. Elamin, A. Rajeh
Summary: The solution casting method was used to produce a new type of nanocomposites made of chitosan, gelatin, and co-doped ZnO nanoparticles. The addition of 3.5% co-doped ZnO nanoparticles improved the physicochemical characteristics and antimicrobial effects of the nanocomposites, indicating their significant potential in food packaging and energy storage.
JOURNAL OF MOLECULAR STRUCTURE
(2024)
Article
Chemistry, Physical
Ruchi Gaur
Summary: The structure and intermolecular interactions of a newly synthesized bis-chalcone THXA were studied using experimental and computational methods. The importance of non-covalent interactions such as pi center dot center dot center dot pi, C-H center dot center dot center dot S, and C-H center dot center dot center dot pi was revealed.
JOURNAL OF MOLECULAR STRUCTURE
(2024)
Article
Chemistry, Physical
Andrii Bazylevich, Leonid Patsenker, Sarit Aviel-Ronen, Gary Gellerman
Summary: Drug combination therapy is commonly used for treating various skin disorders, but its effectiveness is often limited. In this study, researchers synthesized conjugates of anti-pigmenting drugs and hyaluronic acid (HA) to improve treatment efficacy. These HA-drug conjugates exhibited measurable drug release profiles and demonstrated superior depigmentation effects compared to control groups in a swine model.
JOURNAL OF MOLECULAR STRUCTURE
(2024)
Article
Chemistry, Physical
Xiaodan Ma, Xinlei Chen, Yaoqi Zhen, Xunjie Zheng, Chengzhe Shi, Shouwen Jin, Bin Liu, Bin Chen, Daqi Wang
Summary: Cocrystallization experiments between minoxidil and aryl acids coformers resulted in the successful formation of multi-component samples. The nature of these samples was determined using various techniques and their structural and supramolecular aspects were investigated. The outcomes revealed the importance of nonbonding contacts and different types of interactions in stabilizing and expanding the crystal structures.
JOURNAL OF MOLECULAR STRUCTURE
(2024)
Article
Chemistry, Physical
Najla A. Alshaye, Magdy A. Ibrahim, Al-Shimaa Badran
Summary: The chemical behavior of 3-substituted-6,8-dimethylchromones towards phenylhydrazine was examined. Different reaction conditions produced various products, and the molecular geometries and reactivity descriptors of the compounds were also investigated. The results suggest that these compounds are suitable for nonlinear optical applications.
JOURNAL OF MOLECULAR STRUCTURE
(2024)
Article
Chemistry, Physical
Hayette Alliouche, Houria Bouria, Rafik Bensegueni, Mounia Guergouri, Abdelmalek Bouraiou, Ali Belfaitah
Summary: In this paper, a combined experimental and theoretical study was conducted to synthesize and characterize new 2-quinolone-piperidine and -morpholine hybrids. The results from experiments were validated using computational calculations, and the affinity between these compounds and Acetylcholinesterase/Butyrylcholinesterase was estimated through molecular docking.
JOURNAL OF MOLECULAR STRUCTURE
(2024)
Article
Chemistry, Physical
Wei-Min Chen, Juan-Juan Shao, Yi Zhang, Zhen-Dong Xue, Peng-Lai Liu, Jian-Ling Ni, Li-Zhuang Chen, Qiang Gao, Fang-Ming Wang
Summary: This study synthesized and characterized a novel Mn-based LMOF, and achieved good results in detecting heavy metal Al3+ in water, showing good stability, high selectivity and sensitivity. This provides new insights into the potential applications of Mn-based MOFs in chemical sensing.
JOURNAL OF MOLECULAR STRUCTURE
(2024)
Article
Chemistry, Physical
Jun-Xia Li, Yi-Jing Lu, Ke-Ying Quan, Li-Bing Wu, Xun Feng, Wei-Zhou Wang
Summary: This study synthesized two cobalt(II) complexes and analyzed their crystal structures using single-crystal X-ray diffraction. The results showed that the crystal structures of these complexes were different, and they exhibited different crystal packing and magnetic properties.
JOURNAL OF MOLECULAR STRUCTURE
(2024)
Article
Chemistry, Physical
Yang Li, Yan Zhang, Hong Xu, Min Li, Zhen Li, Zi-yu Song, Ji-shi Chen, Yan-Jun Liu, Yong Sun, Zhao Yang
Summary: This study reports the synthesis and solid-state characterization of a new pharmaceutical cocrystal, PRO-BPE, which can enhance the solubility of the highly water-insoluble prodrug probenecid. The PRO-BPE cocrystals were found to have superior water solubility compared to pure PRO. This research provides valuable insights into improving the solubility of poorly soluble drugs.
JOURNAL OF MOLECULAR STRUCTURE
(2024)
Article
Chemistry, Physical
Lucas G. B. Felicio, Bianca B. M. Vieira, Ivana S. Lula, Renata Diniz, Frank Alexis, Flavio B. Miguz, Frederico B. De Sousa
Summary: A novel spiropyran derivative was synthesized for heavy metals sensing in water. The results demonstrated that the new derivative can serve as a rapid, sensitive, and simple tool for detecting Hg2+ ions in water with high selectivity.
JOURNAL OF MOLECULAR STRUCTURE
(2024)
Article
Chemistry, Physical
Junqing Meng, Jie Wang, Lijuan Wang, Chunhui Lyu, Haiyan Chen, Yingpei Lyu, Baisheng Nie
Summary: Material modification with low surface energy can achieve lower surface free energy on micro-and nano-rough structures, which is crucial for developing superhydrophobic surfaces. In this study, attapulgite (APT) was modified with alkylamine, alkylammonium salt, and stearic acid, and the interaction between low surface materials and attapulgite was explained. The results showed that the hydrophobicity of APT was significantly modified by the modifiers, and the surface free energy of the composites first decreased and then increased with increasing molecular number of low surface energy monomers.
JOURNAL OF MOLECULAR STRUCTURE
(2024)
Article
Chemistry, Physical
Karan Goswami, Dipak Das, Parthasarathi Bera, Sounak Roy, Md. Motin Seikh, Prasanta Kumar Sinha, Arup Gayen
Summary: This work presents the development of a simple and highly active heterogeneous Pd catalyst for Suzuki-Miyaura carbon-carbon cross-coupling reaction. The NiPdFe-1 catalyst shows the best activity and stability among the prepared catalysts. It efficiently promotes the coupling reaction between aryl bromide and phenyl boronic acid under mild reaction conditions with high isolated yields.
JOURNAL OF MOLECULAR STRUCTURE
(2024)
Article
Chemistry, Physical
Ekta Pardhi, Devendra Singh Tomar, Rahul Khemchandani, Gananadhamu Samanthula, Pankaj Kumar Singh, Neelesh Kumar Mehra
Summary: The main aim of this study was to prepare a drug-drug coamorphous system to improve the physiochemical properties, solubility and stability of Apremilast and Indomethacin. Various solid-state characterization techniques were used to characterize the prepared system. Molecular level interactions were studied using molecular modeling and ATR-FTIR and 1H NMR. Solubility and dissolution studies showed the benefits of the coamorphous system. The system was found to be stable for a period of five months. Permeation study also demonstrated improved flux for both drugs compared to their crystalline forms. The coamorphous system showed anti-psoriatic and anti-melanogenic activity based on molecular docking results. Overall, the developed CAM-based supersaturated system exhibited improved physicochemical properties and physical stability.
JOURNAL OF MOLECULAR STRUCTURE
(2024)