Investigation on Photo-isomeric Impurity of Roxadustat: Structure Conformation, Physicochemical Characterization, Interconversion Feasibility and in vitro Toxicological Evaluation

A critical review of Roxadustat formulations, solid state studies, and analytical methodology

(2023) Rupali Mahajan et al.   Heliyon

Isolation, identification, structural elucidation, and toxicity prediction using (Q)-SAR models of two degradants: AQbD-driven LC method to determine the Roxadustat impurities

(2023) Srinivas Nakka et al.   Talanta Open

Identification of Hypoxia‐inducible factor (HIF) stabilizer roxadustat and its possible metabolites in thoroughbred horses for doping control

(2021) Binoy Mathew et al.   Drug Testing and Analysis

A Scalable Synthesis of Roxadustat (FG-4592)

(2021) Ondřej Píša et al.   ORGANIC PROCESS RESEARCH & DEVELOPMENT

The prolyl hydroxylase inhibitor roxadustat: Paradigm in drug discovery and prospects for clinical application beyond anemia

(2020) Kaijun Su et al.   DRUG DISCOVERY TODAY

Roxadustat: First Global Approval

(2019) Sohita Dhillon   DRUGS

Hypoxia-Inducible Factor Activators in Renal Anemia: Current Clinical Experience

(2019) Neil S. Sanghani et al.   ADVANCES IN CHRONIC KIDNEY DISEASE

Current regulatory requirements and practical approaches for stability analysis of pharmaceutical products: A comprehensive review

(2018) Pinaki Sengupta et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

SHELXT– Integrated space-group and crystal-structure determination

(2015) George M. Sheldrick   Acta Crystallographica A-Foundation and Advances

Crystal structure refinement withSHELXL

(2015) George M. Sheldrick   Acta Crystallographica Section C-Structural Chemistry

Isolation and characterization of a novel acid degradation impurity of Amlodipine Besylate using Q-TOF, NMR, IR and single crystal X-ray

(2014) Ravi Rapolu et al.   JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS

Recent Trends in Product Development and Regulatory Issues on Impurities in Active Pharmaceutical Ingredient (API) and Drug Products. Part 2: Safety Considerations of Impurities in Pharmaceutical Products and Surveying the Impurity Landscape

(2013) Karen M. Alsante et al.   AAPS PHARMSCITECH

Forced degradation and impurity profiling: Recent trends in analytical perspectives

(2013) Deepti Jain et al.   JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS

A critical review on the use of modern sophisticated hyphenated tools in the characterization of impurities and degradation products

(2012) Saranjit Singh et al.   JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS

OLEX2: a complete structure solution, refinement and analysis program

(2009) Oleg V. Dolomanov et al.   JOURNAL OF APPLIED CRYSTALLOGRAPHY