A novel Dock8 gene mutation confers diabetogenic susceptibility in the LEW.1AR1/Ztm-iddm rat, an animal model of human type 1 diabetes

Dock-family exchange factors in cell migration and disease

(2014) Gilles Gadea et al.   EUROPEAN JOURNAL OF CELL BIOLOGY

DOCK8 is critical for the survival and function of NKT cells

(2013) G. Crawford et al.   BLOOD

Islet infiltration, cytokine expression and beta cell death in the NOD mouse, BB rat, Komeda rat, LEW.1AR1-iddm rat and humans with type 1 diabetes

(2013) Anne Jörns et al.   DIABETOLOGIA

Defective actin accumulation impairs human natural killer cell function in patients with dedicator of cytokinesis 8 deficiency

(2013) Melissa C. Mizesko et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Dedicator of Cytokinesis 8 Interacts with Talin and Wiskott-Aldrich Syndrome Protein To Regulate NK Cell Cytotoxicity

(2013) H. Ham et al.   JOURNAL OF IMMUNOLOGY

DOCK8 is a Cdc42 activator critical for interstitial dendritic cell migration during immune responses

(2012) Y. Harada et al.   BLOOD

The Mst1 and Mst2 kinases control activation of rho family GTPases and thymic egress of mature thymocytes

(2012) Fan Mou et al.   JOURNAL OF EXPERIMENTAL MEDICINE

DOCK8 functions as an adaptor that links TLR-MyD88 signaling to B cell activation

(2012) Haifa H Jabara et al.   NATURE IMMUNOLOGY

DOCK8 is essential for T-cell survival and the maintenance of CD8+ T-cell memory

(2011) Teresa Lambe et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Dedicator of cytokinesis 8 (DOCK8) deficiency

(2010) Helen C Su   Current Opinion in Allergy and Clinical Immunology

Diabetes Prevention by Immunomodulatory FTY720 Treatment in the LEW.1AR1-iddmRat Despite Immune Cell Activation

(2010) Anne Jörns et al.   ENDOCRINOLOGY

Prevention of spontaneous immune-mediated diabetes development in the LEW.1AR1-iddm rat by selective CD8+ T cell transfer is associated with a cytokine shift in the pancreas-draining lymph nodes

(2009) T. Arndt et al.   DIABETOLOGIA

Dock8 mutations cripple B cell immunological synapses, germinal centers and long-lived antibody production

(2009) Katrina L Randall et al.   NATURE IMMUNOLOGY

Combined Immunodeficiency Associated withDOCK8Mutations

(2009) Qian Zhang et al.   NEW ENGLAND JOURNAL OF MEDICINE

Structural specializations of A2, a force-sensing domain in the ultralarge vascular protein von Willebrand factor

(2009) Q. Zhang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Activation of Rho GTPases by DOCK Exchange Factors Is Mediated by a Nucleotide Sensor

(2009) J. Yang et al.   SCIENCE

Impaired survival of peripheral T cells, disrupted NK/NKT cell development, and liver failure in mice lacking Gimap5

(2008) R. D. Schulteis et al.   BLOOD

A genome-wide SNP panel for mapping and association studies in the rat

(2008) Isaäc J Nijman et al.   BMC GENOMICS

Cellular signaling for activation of Rho GTPase Cdc42

(2008) Soniya Sinha et al.   CELLULAR SIGNALLING

The mutation of the LEW.1AR1-iddm rat maps to the telomeric end of rat chromosome 1

(2008) Heike Weiss et al.   MAMMALIAN GENOME

Dock10, a novel CZH protein selectively induced by interleukin-4 in human B lymphocytes

(2008) Estefanía Yelo et al.   MOLECULAR IMMUNOLOGY