FGF21 is not required for glucose homeostasis, ketosis or tumour suppression associated with ketogenic diets in mice

FGF21 Acts Centrally to Induce Sympathetic Nerve Activity, Energy Expenditure, and Weight Loss

(2014) Bryn M. Owen et al.   Cell Metabolism

Thermoneutral housing is a critical factor for immune function and diet-induced obesity in C57BL/6 nude mice

(2014) K Stemmer et al.   INTERNATIONAL JOURNAL OF OBESITY

FGF21 is an endocrine signal of protein restriction

(2014) Thomas Laeger et al.   JOURNAL OF CLINICAL INVESTIGATION

FGF21-based pharmacotherapy – potential utility for metabolic disorders

(2014) Ruth E. Gimeno et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

Ketogenic Diet in Neuromuscular and Neurodegenerative Diseases

(2014) Antonio Paoli et al.   Biomed Research International

Inventing new medicines: The FGF21 story

(2014) Alexei Kharitonenkov et al.   Molecular Metabolism

Roux-en-Y Gastric Bypass Surgery But Not Vertical Sleeve Gastrectomy Decreases Bone Mass in Male Rats

(2013) Kerstin Stemmer et al.   ENDOCRINOLOGY

FGF21 suppresses hepatic glucose production through the activation of atypical protein kinase Cι/λ

(2013) Ling-Jie Kong et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Rational Design of a Fibroblast Growth Factor 21-Based Clinical Candidate, LY2405319

(2013) Alexei Kharitonenkov et al.   PLoS One

LY2405319, an Engineered FGF21 Variant, Improves the Metabolic Status of Diabetic Monkeys

(2013) Andrew C. Adams et al.   PLoS One

Fgf21 Impairs Adipocyte Insulin Sensitivity in Mice Fed a Low-Carbohydrate, High-Fat Ketogenic Diet

(2013) Yusuke Murata et al.   PLoS One

Methionine and choline regulate the metabolic phenotype of a ketogenic diet

(2013) Pavlos Pissios et al.   Molecular Metabolism

Fibroblast growth factor 21 is not required for the antidiabetic actions of the thiazoladinediones

(2013) Andrew C. Adams et al.   Molecular Metabolism

Activating transcription factor 4-dependent induction of FGF21 during amino acid deprivation

(2012) Ana Luísa De Sousa-Coelho et al.   BIOCHEMICAL JOURNAL

Fibroblast Growth Factor-21 Regulates PPARγ Activity and the Antidiabetic Actions of Thiazolidinediones

(2012) Paul A. Dutchak et al.   CELL

Restoration of leptin responsiveness in diet-induced obese mice using an optimized leptin analog in combination with exendin-4 or FGF21

(2012) Timo D. Müller et al.   JOURNAL OF PEPTIDE SCIENCE

Integrated Regulation of Hepatic Metabolism by Fibroblast Growth Factor 21 (FGF21)in Vivo

(2011) ffolliott M. Fisher et al.   ENDOCRINOLOGY

Dietary therapies for epilepsy: Future research

(2011) Sudha K. Kessler et al.   EPILEPSY & BEHAVIOR

A high-fat, ketogenic diet causes hepatic insulin resistance in mice, despite increasing energy expenditure and preventing weight gain

(2010) François R. Jornayvaz et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Induction of ketosis in rats fed low-carbohydrate, high-fat diets depends on the relative abundance of dietary fat and protein

(2010) Maximilian Bielohuby et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Fibroblast Growth Factor 21 Action in the Brain Increases Energy Expenditure and Insulin Sensitivity in Obese Rats

(2010) D. A. Sarruf et al.   DIABETES

Increased Fibroblast Growth Factor 21 in Obesity and Nonalcoholic Fatty Liver Disease

(2010) Jody Dushay et al.   GASTROENTEROLOGY

Carbohydrate for weight and metabolic control: Where do we stand?

(2010) Kevin J. Acheson   NUTRITION

Fibroblast Growth Factor 21-Deficient Mice Demonstrate Impaired Adaptation to Ketosis

(2009) Michael K. Badman et al.   ENDOCRINOLOGY

Fibroblast Growth Factor 21 Regulates Lipolysis in White Adipose Tissue But Is Not Required for Ketogenesis and Triglyceride Clearance in Liver

(2009) Yuhei Hotta et al.   ENDOCRINOLOGY

Phosphoenolpyruvate Cycling via Mitochondrial Phosphoenolpyruvate Carboxykinase Links Anaplerosis and Mitochondrial GTP with Insulin Secretion

(2009) Romana Stark et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Circulating Fibroblast Growth Factor 21 Is Induced by Peroxisome Proliferator-Activated Receptor Agonists But Not Ketosis in Man

(2009) Constantinos Christodoulides et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

FGF21 induces PGC-1  and regulates carbohydrate and fatty acid metabolism during the adaptive starvation response

(2009) M. J. Potthoff et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Circulating Metabolic Regulator FGF21 Is Induced by Prolonged Fasting and PPARα Activation in Man

(2008) Cecilia Gälman et al.   Cell Metabolism

Fibroblast Growth Factor 21 Reverses Hepatic Steatosis, Increases Energy Expenditure, and Improves Insulin Sensitivity in Diet-Induced Obese Mice

(2008) J. Xu et al.   DIABETES

Fibroblast Growth Factor 21 Corrects Obesity in Mice

(2008) Tamer Coskun et al.   ENDOCRINOLOGY