标题
Rational Design of a Fibroblast Growth Factor 21-Based Clinical Candidate, LY2405319
作者
关键词
-
出版物
PLoS One
Volume 8, Issue 3, Pages e58575
出版商
Public Library of Science (PLoS)
发表日期
2013-03-12
DOI
10.1371/journal.pone.0058575
参考文献
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- (2012) David E. Moller Cell Metabolism
- Long-Acting FGF21 Has Enhanced Efficacy in Diet-Induced Obese Mice and in Obese Rhesus Monkeys
- (2012) Murielle M. Véniant et al. ENDOCRINOLOGY
- Immunogenicity of protein aggregates—Concerns and realities
- (2012) Wei Wang et al. INTERNATIONAL JOURNAL OF PHARMACEUTICS
- Restoration of leptin responsiveness in diet-induced obese mice using an optimized leptin analog in combination with exendin-4 or FGF21
- (2012) Timo D. Müller et al. JOURNAL OF PEPTIDE SCIENCE
- Fundamentals of FGF19 & FGF21 Action In Vitro and In Vivo
- (2012) Andrew C. Adams et al. PLoS One
- FGF21 Requires βklotho to Act In Vivo
- (2012) Andrew C. Adams et al. PLoS One
- FGF21 Analogs of Sustained Action Enabled by Orthogonal Biosynthesis Demonstrate Enhanced Antidiabetic Pharmacology in Rodents
- (2011) J. Mu et al. DIABETES
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- (2011) Wei Chen et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Hormone-like (endocrine) Fgfs: their evolutionary history and roles in development, metabolism, and disease
- (2010) Nobuyuki Itoh CELL AND TISSUE RESEARCH
- Lessons from the lysozyme of phage T4
- (2010) Walter A. Baase et al. PROTEIN SCIENCE
- FGF21 reloaded: challenges of a rapidly growing field
- (2010) Alexei Kharitonenkov et al. TRENDS IN ENDOCRINOLOGY AND METABOLISM
- Different roles of N- and C- termini in the functional activity of FGF21
- (2009) Radmila Micanovic et al. JOURNAL OF CELLULAR PHYSIOLOGY
- Fibroblast Growth Factor 21 Reverses Hepatic Steatosis, Increases Energy Expenditure, and Improves Insulin Sensitivity in Diet-Induced Obese Mice
- (2008) J. Xu et al. DIABETES
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- (2008) Tamer Coskun et al. ENDOCRINOLOGY
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- (2008) Junming Yie et al. FEBS LETTERS
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- FGF-21/FGF-21 receptor interaction and activation is determined by βKlotho
- (2007) Alexei Kharitonenkov et al. JOURNAL OF CELLULAR PHYSIOLOGY
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