Lipid metabolism and its implications for type 1 diabetes-associated cardiomyopathy

Lipid Use and Misuse by the Heart

(2016) P. Christian Schulze et al.   CIRCULATION RESEARCH

Lactosylceramide contributes to mitochondrial dysfunction in diabetes

(2016) Sergei A. Novgorodov et al.   JOURNAL OF LIPID RESEARCH

Ablation of Matrix Metalloproteinase-9 Prevents Cardiomyocytes Contractile Dysfunction in Diabetics

(2016) Priyanka Prathipati et al.   Frontiers in Physiology

MK2 Deletion in Mice Prevents Diabetes-Induced Perturbations in Lipid Metabolism and Cardiac Dysfunction

(2015) Matthieu Ruiz et al.   DIABETES

FGF21 deletion exacerbates diabetic cardiomyopathy by aggravating cardiac lipid accumulation

(2015) Xiaoqing Yan et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Adeno-Associated Virus Vectors as Therapeutic and Investigational Tools in the Cardiovascular System

(2014) Serena Zacchigna et al.   CIRCULATION RESEARCH

Molecular mechanisms of diabetic cardiomyopathy

(2014) Heiko Bugger et al.   DIABETOLOGIA

Deficiency of a Lipid Droplet Protein, Perilipin 5, Suppresses Myocardial Lipid Accumulation, Thereby Preventing Type 1 Diabetes-Induced Heart Malfunction

(2014) K. Kuramoto et al.   MOLECULAR AND CELLULAR BIOLOGY

Diabetic cardiomyopathy: Mechanisms and new treatment strategies targeting antioxidant signaling pathways

(2014) Karina Huynh et al.   PHARMACOLOGY & THERAPEUTICS

Differential Expression of Dicer, miRNAs, and Inflammatory Markers in Diabetic Ins2+/− Akita Hearts

(2013) Vishalakshi Chavali et al.   CELL BIOCHEMISTRY AND BIOPHYSICS

Myocardial Adipose Triglyceride Lipase Overexpression Protects Diabetic Mice From the Development of Lipotoxic Cardiomyopathy

(2013) T. Pulinilkunnil et al.   DIABETES

Diminished Autophagy Limits Cardiac Injury in Mouse Models of Type 1 Diabetes

(2013) Xianmin Xu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A largely random AAV integration profile after LPLD gene therapy

(2013) Christine Kaeppel et al.   NATURE MEDICINE

Taking Diabetes to Heart—Deregulation of Myocardial Lipid Metabolism in Diabetic Cardiomyopathy

(2013) Marina Bayeva et al.   Journal of the American Heart Association

Na+/Ca2+ exchanger-1 protects against systolic failure in the Akitains2 model of diabetic cardiomyopathy via a CXCR4/NF-κB pathway

(2012) Thomas J. LaRocca et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Therapeutic effect of MG-132 on diabetic cardiomyopathy is associated with its suppression of proteasomal activities: roles of Nrf2 and NF-κB

(2012) Yuehui Wang et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Metabolic inflexibility and protein lysine acetylation in heart mitochondria of a chronic model of Type 1 diabetes

(2012) Shraddha S. Vadvalkar et al.   BIOCHEMICAL JOURNAL

Lipid Metabolism and Toxicity in the Heart

(2012) Ira J. Goldberg et al.   Cell Metabolism

Direct renin inhibition prevents cardiac dysfunction in a diabetic mouse model: comparison with an angiotensin receptor antagonist and angiotensin-converting enzyme inhibitor

(2012) Candice M. Thomas et al.   CLINICAL SCIENCE

CD36 as a target to prevent cardiac lipotoxicity and insulin resistance

(2012) Jan F.C. Glatz et al.   PROSTAGLANDINS LEUKOTRIENES AND ESSENTIAL FATTY ACIDS

Improvement of Cardiac Functions by Chronic Metformin Treatment Is Associated With Enhanced Cardiac Autophagy in Diabetic OVE26 Mice

(2011) Z. Xie et al.   DIABETES

Targeted Inhibition of Calpain Reduces Myocardial Hypertrophy and Fibrosis in Mouse Models of Type 1 Diabetes

(2011) Ying Li et al.   DIABETES

Attenuation of beta2-adrenergic receptors and homocysteine metabolic enzymes cause diabetic cardiomyopathy

(2010) Paras Kumar Mishra et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

MAPK-Activated Protein Kinase-2 in Cardiac Hypertrophy and Cyclooxygenase-2 Regulation in Heart

(2010) John M. Streicher et al.   CIRCULATION RESEARCH

Cardiac-Specific IGF-1 Receptor Transgenic Expression Protects Against Cardiac Fibrosis and Diastolic Dysfunction in a Mouse Model of Diabetic Cardiomyopathy

(2010) K. Huynh et al.   DIABETES

Role of fatty acid uptake and fatty acid β-oxidation in mediating insulin resistance in heart and skeletal muscle

(2009) Liyan Zhang et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

Role of SREBP-1 in the Development of Parasympathetic Dysfunction in the Hearts of Type 1 Diabetic Akita Mice

(2009) Ho-Jin Park et al.   CIRCULATION RESEARCH

Hyperglycemia-Induced Reactive Oxygen Species Increase Expression of the Receptor for Advanced Glycation End Products (RAGE) and RAGE Ligands

(2009) D. Yao et al.   DIABETES

Gene Deletion of the Kinin Receptor B1 Attenuates Cardiac Inflammation and Fibrosis During the Development of Experimental Diabetic Cardiomyopathy

(2009) D. Westermann et al.   DIABETES

Tissue-Specific Remodeling of the Mitochondrial Proteome in Type 1 Diabetic Akita Mice

(2009) H. Bugger et al.   DIABETES

Diagnosis and Classification of Diabetes Mellitus

(2009)   DIABETES CARE

Substrate-Specific Derangements in Mitochondrial Metabolism and Redox Balance in the Atrium of the Type 2 Diabetic Human Heart

(2009) Ethan J. Anderson et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Cardiac overexpression of hormone-sensitive lipase inhibits myocardial steatosis and fibrosis in streptozotocin diabetic mice

(2008) Masami Ueno et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Mitochondrial Overload and Incomplete Fatty Acid Oxidation Contribute to Skeletal Muscle Insulin Resistance

(2008) Timothy R. Koves et al.   Cell Metabolism

Type 1 Diabetic Akita Mouse Hearts Are Insulin Sensitive but Manifest Structurally Abnormal Mitochondria That Remain Coupled Despite Increased Uncoupling Protein 3

(2008) H. Bugger et al.   DIABETES

Short-Term Hyperglycemic Dysregulation in Patients With Type 1 Diabetes Does Not Change Myocardial Triglyceride Content or Myocardial Function

(2008) S. Hammer et al.   DIABETES CARE

The Role of Advanced Glycation End Products in Progression and Complications of Diabetes

(2008) Su-Yen Goh et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Myocardial Steatosis Is an Independent Predictor of Diastolic Dysfunction in Type 2 Diabetes Mellitus

(2008) Luuk J. Rijzewijk et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY