Trisubstituted Imidazoles with a Rigidized Hinge Binding Motif Act As Single Digit nM Inhibitors of Clinically Relevant EGFR L858R/T790M and L858R/T790M/C797S Mutants: An Example of Target Hopping

标题
Trisubstituted Imidazoles with a Rigidized Hinge Binding Motif Act As Single Digit nM Inhibitors of Clinically Relevant EGFR L858R/T790M and L858R/T790M/C797S Mutants: An Example of Target Hopping
作者
关键词
-
出版物
JOURNAL OF MEDICINAL CHEMISTRY
Volume 60, Issue 11, Pages 4636-4656
出版商
American Chemical Society (ACS)
发表日期
2017-05-09
DOI
10.1021/acs.jmedchem.7b00178

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