Teleost-Specific TLR19 Localizes to Endosome, Recognizes dsRNA, Recruits TRIF, Triggers both IFN and NF-κB Pathways, and Protects Cells from Grass Carp Reovirus Infection

Grass Carp Laboratory of Genetics and Physiology 2 Serves As a Negative Regulator in Retinoic Acid-Inducible Gene I- and Melanoma Differentiation-Associated Gene 5-Mediated Antiviral Signaling in Resting State and Early Stage of Grass Carp Reovirus Infection

(2017) Youliang Rao et al.   Frontiers in Immunology

MDA5 Induces a Stronger Interferon Response than RIG-I to GCRV Infection through a Mechanism Involving the Phosphorylation and Dimerization of IRF3 and IRF7 in CIK Cells

(2017) Quanyuan Wan et al.   Frontiers in Immunology

Bioinformatics analysis of organizational and expressional characterizations of the IFNs, IRFs and CRFBs in grass carp Ctenopharyngodon idella

(2016) Zhiwei Liao et al.   DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY

Two novel LRR-only proteins in Chlamys farreri: Similar in structure, yet different in expression profile and pattern recognition

(2016) Mengqiang Wang et al.   DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY

IRF7 inhibition prevents destructive innate immunity—A target for nonantibiotic therapy of bacterial infections

(2016) Manoj Puthia et al.   Science Translational Medicine

Functional characterizations of IPS-1 in CIK cells: Potential roles in regulating IFN-I response dependent on IRF7 but not IRF3

(2015) Xiaoli Feng et al.   DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY

Grass carp SARM1 and its two splice variants negatively regulate IFN-I response and promote cell death upon GCRV infection at different subcellular locations

(2015) Nana Yan et al.   DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY

Structural and evolutionary characteristics of fish-specific TLR19

(2015) Jinlan Wang et al.   FISH & SHELLFISH IMMUNOLOGY

Transcriptome analysis provides insights into the regulatory function of alternative splicing in antiviral immunity in grass carp (Ctenopharyngodon idella)

(2015) Quanyuan Wan et al.   Scientific Reports

Comparative studies of Toll-like receptor signalling using zebrafish

(2014) Zakia Kanwal et al.   DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY

Toll-like receptor recognition of bacteria in fish: Ligand specificity and signal pathways

(2014) Jie Zhang et al.   FISH & SHELLFISH IMMUNOLOGY

Identification and characterisation of TLR18-21 genes in Atlantic salmon (Salmo salar)

(2014) P.T. Lee et al.   FISH & SHELLFISH IMMUNOLOGY

Teleost TLR22 Recognizes RNA Duplex to Induce IFN and Protect Cells from Birnaviruses

(2014) A. Matsuo et al.   JOURNAL OF IMMUNOLOGY

IFN Regulatory Factor 10 Is a Negative Regulator of the IFN Responses in Fish

(2014) S. Li et al.   JOURNAL OF IMMUNOLOGY

Pathogen recognition receptors in channel catfish: III Phylogeny and expression analysis of Toll-like receptors

(2013) Jiaren Zhang et al.   DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY

Expression profiles of toll-like receptors in channel catfish (Ictalurus punctatus) after infection with Ichthyophthirius multifiliis

(2013) Fei Zhao et al.   FISH & SHELLFISH IMMUNOLOGY

Gig1, a novel antiviral effector involved in fish interferon response

(2013) Fan Sun et al.   VIROLOGY

Molecular regulation of interferon antiviral response in fish

(2012) Yi-Bing Zhang et al.   DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY

Protective Roles of Grass Carp Ctenopharyngodon idella Mx Isoforms against Grass Carp Reovirus

(2012) Limin Peng et al.   PLoS One

Teleost fish interferons and their role in immunity

(2011) Jun Zou et al.   DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY

Toll-like receptors in bony fish: From genomics to function

(2011) Yniv Palti   DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY

Toll-like Receptors and Their Crosstalk with Other Innate Receptors in Infection and Immunity

(2011) Taro Kawai et al.   IMMUNITY

Fish MITA Serves as a Mediator for Distinct Fish IFN Gene Activation Dependent on IRF3 or IRF7

(2011) F. Sun et al.   JOURNAL OF IMMUNOLOGY

Intracellular Toll-like Receptors

(2010) Amanda L. Blasius et al.   IMMUNITY

Characterization of Fish IRF3 as an IFN-Inducible Protein Reveals Evolving Regulation of IFN Response in Vertebrates

(2010) F. Sun et al.   JOURNAL OF IMMUNOLOGY

Fish virus-induced interferon exerts antiviral function through Stat1 pathway

(2010) Fei-Fei Yu et al.   MOLECULAR IMMUNOLOGY

Structural conservation of interferon gamma among vertebrates

(2009) Ram Savan et al.   CYTOKINE & GROWTH FACTOR REVIEWS

Toll-like receptor signaling in bony fish

(2009) Alexander Rebl et al.   VETERINARY IMMUNOLOGY AND IMMUNOPATHOLOGY

The Adaptor Protein MITA Links Virus-Sensing Receptors to IRF3 Transcription Factor Activation

(2008) Bo Zhong et al.   IMMUNITY