Prolonged Ischemia Triggers Necrotic Depletion of Tissue-Resident Macrophages To Facilitate Inflammatory Immune Activation in Liver Ischemia Reperfusion Injury

The Dichotomy of Endoplasmic Reticulum Stress Response in Liver Ischemia-Reperfusion Injury

(2016) Haomming Zhou et al.   TRANSPLANTATION

Liver-Resident Macrophage Necroptosis Orchestrates Type 1 Microbicidal Inflammation and Type-2-Mediated Tissue Repair during Bacterial Infection

(2015) Camille Blériot et al.   IMMUNITY

Tissue-resident macrophages: then and now

(2015) Luke C. Davies et al.   IMMUNOLOGY

Endoplasmic reticulum stress induces ligand-independent TNFR1-mediated necroptosis in L929 cells

(2015) S Saveljeva et al.   Cell Death & Disease

ATF6 Mediates a Pro-Inflammatory Synergy Between ER Stress and TLR Activation in the Pathogenesis of Liver Ischemia-Reperfusion Injury

(2014) J. Rao et al.   AMERICAN JOURNAL OF TRANSPLANTATION

T-cell immunoglobulin and mucin domain 4 (TIM-4) signaling in innate immune-mediated liver ischemia-reperfusion injury

(2014) Haofeng Ji et al.   HEPATOLOGY

Infiltrating Monocyte-Derived Macrophages and Resident Kupffer Cells Display Different Ontogeny and Functions in Acute Liver Injury

(2014) E. Zigmond et al.   JOURNAL OF IMMUNOLOGY

Tissue-resident macrophages originate from yolk-sac-derived erythro-myeloid progenitors

(2014) Elisa Gomez Perdiguero et al.   NATURE

Type-I interferon signaling through ISGF3 complex is required for sustained Rip3 activation and necroptosis in macrophages

(2014) S. McComb et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

RIPK3-Mediated Necroptosis Promotes Donor Kidney Inflammatory Injury and Reduces Allograft Survival

(2013) A. Lau et al.   AMERICAN JOURNAL OF TRANSPLANTATION

Tissue-Resident Macrophages Self-Maintain Locally throughout Adult Life with Minimal Contribution from Circulating Monocytes

(2013) Daigo Hashimoto et al.   IMMUNITY

Necroptosis: The Release of Damage-Associated Molecular Patterns and Its Physiological Relevance

(2013) Agnieszka Kaczmarek et al.   IMMUNITY

Toll-like Receptor 3-mediated Necrosis via TRIF, RIP3, and MLKL

(2013) William J. Kaiser et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

GPR120 on Kupffer cells mediates hepatoprotective effects of ω3-fatty acids

(2013) Dimitri Aristotle Raptis et al.   JOURNAL OF HEPATOLOGY

Distinct development and functions of resident and recruited liver Kupffer cells/macrophages

(2013) Masami Ikarashi et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Tissue-resident macrophages

(2013) Luke C Davies et al.   NATURE IMMUNOLOGY

The Transcription Factor IRF3 Triggers “Defensive Suicide” Necrosis in Response to Viral and Bacterial Pathogens

(2013) Nelson C. Di Paolo et al.   Cell Reports

Fate Mapping Reveals Origins and Dynamics of Monocytes and Tissue Macrophages under Homeostasis

(2012) Simon Yona et al.   IMMUNITY

Kupffer cells express a unique combination of phenotypic and functional characteristics compared with splenic and peritoneal macrophages

(2012) Dowty Movita et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Rip1 (Receptor-interacting protein kinase 1) mediates necroptosis and contributes to renal ischemia/reperfusion injury

(2012) Andreas Linkermann et al.   KIDNEY INTERNATIONAL

Type I interferon induces necroptosis in macrophages during infection with Salmonella enterica serovar Typhimurium

(2012) Nirmal Robinson et al.   NATURE IMMUNOLOGY

A Lineage of Myeloid Cells Independent of Myb and Hematopoietic Stem Cells

(2012) C. Schulz et al.   SCIENCE

Endoplasmic Reticulum Stress Modulates Liver Inflammatory Immune Response in the Pathogenesis of Liver Ischemia and Reperfusion Injury

(2012) Jun Liu et al.   TRANSPLANTATION

Necrostatin-1 analogues: critical issues on the specificity, activity and in vivo use in experimental disease models

(2012) N Takahashi et al.   Cell Death & Disease

Liver Ischemia and Reperfusion Injury: New Insights into Mechanisms of Innate-Adaptive Immune-Mediated Tissue Inflammation

(2011) Y. Zhai et al.   AMERICAN JOURNAL OF TRANSPLANTATION

Many stimuli pull the necrotic trigger, an overview

(2011) N Vanlangenakker et al.   CELL DEATH AND DIFFERENTIATION

Ischemia and reperfusion—from mechanism to translation

(2011) Holger K Eltzschig et al.   NATURE MEDICINE

Synergistic protective effects of humanin and necrostatin-1 on hypoxia and ischemia/reperfusion injury

(2010) Xingshun Xu et al.   BRAIN RESEARCH

MicroRNA-155 prevents necrotic cell death in human cardiomyocyte progenitor cells via targeting RIP1

(2010) Jia Liu et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Characterization of two F4/80-positive Kupffer cell subsets by their function and phenotype in mice

(2010) Manabu Kinoshita et al.   JOURNAL OF HEPATOLOGY

Murine Kupffer Cells Are Protective in Total Hepatic Ischemia/Reperfusion Injury with Bowel Congestion through IL-10

(2010) J. D. Ellett et al.   JOURNAL OF IMMUNOLOGY

Tissue-resident Macrophages Protect the Liver From Ischemia Reperfusion Injury via a Heme Oxygenase-1-Dependent Mechanism

(2008) Luke Devey et al.   MOLECULAR THERAPY