HERP Binds TBK1 To Activate Innate Immunity and Repress Virus Replication in Response to Endoplasmic Reticulum Stress

Amplified RLR signaling activation through an interferon-stimulated gene-endoplasmic reticulum stress-mitochondrial calcium uniporter protein loop

(2016) Jinbo Cheng et al.   Scientific Reports

Enterovirus 71 induces dsRNA/PKR-dependent cytoplasmic redistribution of GRP78/BiP to promote viral replication

(2016) Jia-Rong Jheng et al.   Emerging Microbes & Infections

Induction of Herpud1 expression by ER stress is regulated by Nrf1

(2015) Daniel V. Ho et al.   FEBS LETTERS

Interferon-λ restricts West Nile virus neuroinvasion by tightening the blood-brain barrier

(2015) Helen M. Lazear et al.   Science Translational Medicine

RIG-I in RNA virus recognition

(2015) Alison M. Kell et al.   VIROLOGY

Dengue Virus NS Proteins Inhibit RIG-I/MAVS Signaling by Blocking TBK1/IRF3 Phosphorylation: Dengue Virus Serotype 1 NS4A Is a Unique Interferon-Regulating Virulence Determinant

(2015) Nadine A. Dalrymple et al.   mBio

The ER-Associated Protein ZDHHC1 Is a Positive Regulator of DNA Virus-Triggered, MITA/STING-Dependent Innate Immune Signaling

(2014) Qian Zhou et al.   Cell Host & Microbe

Hantavirus GnT Elements Mediate TRAF3 Binding and Inhibit RIG-I/TBK1-Directed Beta Interferon Transcription by Blocking IRF3 Phosphorylation

(2014) V. S. Matthys et al.   JOURNAL OF VIROLOGY

Herp coordinates compartmentalization and recruitment of HRD1 and misfolded proteins for ERAD

(2014) Julia Leitman et al.   MOLECULAR BIOLOGY OF THE CELL

Bacteria, the endoplasmic reticulum and the unfolded protein response: friends or foes?

(2014) Jean Celli et al.   NATURE REVIEWS MICROBIOLOGY

PolyC-Binding Protein 1 Interacts with 5′-Untranslated Region of Enterovirus 71 RNA in Membrane-Associated Complex to Facilitate Viral Replication

(2014) Zhen Luo et al.   PLoS One

Amerindian-specific regions under positive selection harbour new lipid variants in Latinos

(2014) Arthur Ko et al.   Nature Communications

Update on enterovirus 71 infection

(2014) Peng-Nien Huang et al.   Current Opinion in Virology

A novel mechanism regulating insulin secretion involving Herpud1 in mice

(2013) N. Wong et al.   DIABETOLOGIA

IL-27, a Cytokine, and IFN- 1, a Type III IFN, Are Coordinated To Regulate Virus Replication through Type I IFN

(2013) Y. Cao et al.   JOURNAL OF IMMUNOLOGY

HCV-Induced miR-21 Contributes to Evasion of Host Immune System by Targeting MyD88 and IRAK1

(2013) Yanni Chen et al.   PLoS Pathogens

Excessive proinflammatory cytokine and chemokine responses of human monocyte-derived macrophages to enterovirus 71 infection

(2012) Xun Gong et al.   BMC INFECTIOUS DISEASES

Major vault protein: A virus-induced host factor against viral replication through the induction of type-I interferon

(2012) Shi Liu et al.   HEPATOLOGY

Hepatitis B Virus-Induced Calreticulin Protein Is Involved in IFN Resistance

(2012) X. Yue et al.   JOURNAL OF IMMUNOLOGY

In Enterovirus 71 Encephalitis With Cardio-Respiratory Compromise, Elevated Interleukin 1 , Interleukin 1 Receptor Antagonist, and Granulocyte Colony-Stimulating Factor Levels Are Markers of Poor Prognosis

(2012) M. J. Griffiths et al.   JOURNAL OF INFECTIOUS DISEASES

Crystal Structure of Human Enterovirus 71

(2012) P. Plevka et al.   SCIENCE

MicroRNA-548 down-regulates host antiviral response via direct targeting of IFN-λ1

(2012) Yongkui Li et al.   Protein & Cell

Macrophages are important mediators of either tumor- or inflammation-induced lymphangiogenesis

(2011) Rui-Cheng Ji   CELLULAR AND MOLECULAR LIFE SCIENCES

Viral Reorganization of the Secretory Pathway Generates Distinct Organelles for RNA Replication

(2010) Nai-Yun Hsu et al.   CELL

Pattern Recognition Receptors and Inflammation

(2010) Osamu Takeuchi et al.   CELL

Endoplasmic reticulum stress is induced and modulated by enterovirus 71

(2010) Jia-Rong Jheng et al.   CELLULAR MICROBIOLOGY

Herp Regulates Hrd1-mediated Ubiquitylation in a Ubiquitin-like Domain-dependent Manner

(2010) Melanie Kny et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Endoplasmic Reticulum Stress-Inducible Protein, Herp, Is a Potential Triggering Antigen for Anti-DNA Response

(2010) Y. Hirabayashi et al.   JOURNAL OF IMMUNOLOGY

The Homocysteine-inducible Endoplasmic Reticulum Stress Protein Counteracts Calcium Store Depletion and Induction of CCAAT Enhancer-binding Protein Homologous Protein in a Neurotoxin Model of Parkinson Disease

(2009) Srinivasulu Chigurupati et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Cotranslational Targeting of XBP1 Protein to the Membrane Promotes Cytoplasmic Splicing of Its Own mRNA

(2009) Kota Yanagitani et al.   MOLECULAR CELL

Antiviral activity of type I interferons and interleukins 29 and 28a (type III interferons) against Apeu virus

(2008) G ALMEIDA et al.   ANTIVIRAL RESEARCH

Interferons: Signaling, antiviral and viral evasion

(2008) Cláudio A. Bonjardim et al.   IMMUNOLOGY LETTERS