Two common variants of human papillomavirus type 16 E6 differentially deregulate sugar metabolism and hypoxia signalling in permissive human keratinocytes

PKM2 contributes to cancer metabolism

(2015) Nicholas Wong et al.   CANCER LETTERS

The human papillomavirus 16 European-T350G E6 variant can immortalize but not transform keratinocytes in the absence of E7

(2015) Melissa Togtema et al.   VIROLOGY

Hypoxia-inducible factor 1 and its role in viral carcinogenesis

(2014) Sean Cuninghame et al.   VIROLOGY

Quantitative determinants of aerobic glycolysis identify flux through the enzyme GAPDH as a limiting step

(2014) Alexander A Shestov et al.   eLife

Acidity Generated by the Tumor Microenvironment Drives Local Invasion

(2013) V. Estrella et al.   CANCER RESEARCH

Prognostic assessment of hypoxia and metabolic markers in cervical cancer using automated digital image analysis of immunohistochemistry

(2013) Bo Kim et al.   Journal of Translational Medicine

The human papillomavirus family and its role in carcinogenesis

(2013) Massimo Tommasino   SEMINARS IN CANCER BIOLOGY

Targeting the MAPK–RAS–RAF signaling pathway in cancer therapy

(2012) Libero Santarpia et al.   EXPERT OPINION ON THERAPEUTIC TARGETS

The Asian-American E6 Variant Protein of Human Papillomavirus 16 Alone Is Sufficient To Promote Immortalization, Transformation, and Migration of Primary Human Foreskin Keratinocytes

(2012) S. Niccoli et al.   JOURNAL OF VIROLOGY

HPV: The global burden

(2012) James Mitchell Crow   NATURE

Bortezomib represses HIF-1α protein expression and nuclear accumulation by inhibiting both PI3K/Akt/TOR and MAPK pathways in prostate cancer cells

(2011) Christina D. Befani et al.   JOURNAL OF MOLECULAR MEDICINE-JMM

The immortalizing and transforming ability of two common human papillomavirus 16 E6 variants with different prevalences in cervical cancer

(2010) C Richard et al.   ONCOGENE

Association of HPV16 E6 variants with diagnostic severity in cervical cytology samples of 354 women in a US population

(2009) Rosemary E. Zuna et al.   INTERNATIONAL JOURNAL OF CANCER

Understanding the Warburg Effect: The Metabolic Requirements of Cell Proliferation

(2009) M. G. Vander Heiden et al.   SCIENCE

Hypoxia-Inducible Carbonic Anhydrase IX and XII Promote Tumor Cell Growth by Counteracting Acidosis through the Regulation of the Intracellular pH

(2008) J. Chiche et al.   CANCER RESEARCH

Cancer Cell Metabolism: Warburg and Beyond

(2008) Peggy P. Hsu et al.   CELL

Human papillomavirus 16 E6 variants differ in their dysregulation of human keratinocyte differentiation and apoptosis

(2008) Ingeborg Zehbe et al.   VIROLOGY