Quantitative assessment of specific carbonic anhydrase inhibitors effect on hypoxic cells using electrical impedance assays

Structure and function of carbonic anhydrases

(2016) C. T. Supuran   BIOCHEMICAL JOURNAL

Advances in structure-based drug discovery of carbonic anhydrase inhibitors

(2016) Claudiu T. Supuran   Expert Opinion on Drug Discovery

The extracellular matrix protein laminin-10 promotes blood–brain barrier repair after hypoxia and inflammation in vitro

(2016) Korakoch Kangwantas et al.   Journal of Neuroinflammation

Hypoxia and metabolic adaptation of cancer cells

(2016) K L Eales et al.   Oncogenesis

Hypoxia Induces Autophagy through Translational Up-Regulation of Lysosomal Proteins in Human Colon Cancer Cells

(2016) Ming-Chih Lai et al.   PLoS One

In a search for selective inhibitors of carbonic anhydrases: coumarin and its bioisosteres – synthesis and derivatization

(2015) Raivis Žalubovskis   Chemistry of Heterocyclic Compounds

7-Aryl-triazolyl-substituted sulfocoumarins are potent, selective inhibitors of the tumor-associated carbonic anhydrase IX and XII

(2015) Alessio Nocentini et al.   JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY

How many carbonic anhydrase inhibition mechanisms exist?

(2015) Claudiu T. Supuran   JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY

6-Substituted Sulfocoumarins Are Selective Carbonic Anhdydrase IX and XII Inhibitors with Significant Cytotoxicity against Colorectal Cancer Cells

(2015) Aiga Grandane et al.   JOURNAL OF MEDICINAL CHEMISTRY

Hypoxia Differentially Regulates Arterial and Venous Smooth Muscle Cell Migration

(2015) Alice Chanakira et al.   PLoS One

Recent Developments in Targeting Carbonic Anhydrase IX for Cancer Therapeutics

(2015) Paul C. McDonald et al.   Oncotarget

Sulfonamides and their isosters as carbonic anhydrase inhibitors

(2014) Fabrizio Carta et al.   Future Medicinal Chemistry

7-Substituted-sulfocoumarins are isoform-selective, potent carbonic anhydrase II inhibitors

(2013) Muhammet Tanc et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Label free sensing platform for amyloid fibrils effect on living cells

(2013) Mihaela Gheorghiu et al.   BIOSENSORS & BIOELECTRONICS

Multiple Binding Modes of Inhibitors to Carbonic Anhydrases: How to Design Specific Drugs Targeting 15 Different Isoforms?

(2012) Vincenzo Alterio et al.   CHEMICAL REVIEWS

Sulfocoumarins (1,2-Benzoxathiine-2,2-dioxides): A Class of Potent and Isoform-Selective Inhibitors of Tumor-Associated Carbonic Anhydrases

(2012) Kaspars Tars et al.   JOURNAL OF MEDICINAL CHEMISTRY

Facile synthesis of coumarin bioisosteres—1,2-benzoxathiine 2,2-dioxides

(2012) Aiga Grandane et al.   TETRAHEDRON

Targeting Tumor Hypoxia: Suppression of Breast Tumor Growth and Metastasis by Novel Carbonic Anhydrase IX Inhibitors

(2011) Y. Lou et al.   CANCER RESEARCH

Carbonic anhydrase inhibitors and activators for novel therapeutic applications

(2011) Claudiu T Supuran   Future Medicinal Chemistry

Interfering with pH regulation in tumours as a therapeutic strategy

(2011) Dario Neri et al.   NATURE REVIEWS DRUG DISCOVERY

Specific inhibition of carbonic anhydrase IX activity enhances the in vivo therapeutic effect of tumor irradiation

(2011) Ludwig Dubois et al.   RADIOTHERAPY AND ONCOLOGY

Electrical cell-substrate impedance sensing as a non-invasive tool for cancer cell study

(2010) Jongin Hong et al.   ANALYST

Cellular electrical impedance spectroscopy: an emerging technology of microscale biosensors

(2010) Wenwen Gu et al.   Expert Review of Medical Devices

A microelectrode-based sensor for label-free in vitro detection of ischemic effects on cardiomyocytes

(2009) Dana Krinke et al.   BIOSENSORS & BIOELECTRONICS

Kinetic Cell-Based Morphological Screening: Prediction of Mechanism of Compound Action and Off-Target Effects

(2009) Yama A. Abassi et al.   CHEMISTRY & BIOLOGY

Imaging of CA IX with fluorescent labelled sulfonamides distinguishes hypoxic and (re)-oxygenated cells in a xenograft tumour model

(2009) Ludwig Dubois et al.   RADIOTHERAPY AND ONCOLOGY

Mitochondrial Autophagy Is an HIF-1-dependent Adaptive Metabolic Response to Hypoxia

(2008) Huafeng Zhang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Therapeutic applications of glycosidic carbonic anhydrase inhibitors

(2008) Jean-Yves Winum et al.   MEDICINAL RESEARCH REVIEWS

Carbonic anhydrases: novel therapeutic applications for inhibitors and activators

(2008) Claudiu T. Supuran   NATURE REVIEWS DRUG DISCOVERY