Cysteamine prevents vascular leakage through inhibiting transglutaminase in diabetic retina

Essential Role of Transglutaminase 2 in Vascular Endothelial Growth Factor–Induced Vascular Leakage in the Retina of Diabetic Mice

(2016) Yeon-Ju Lee et al.   DIABETES

Current and investigational drugs for the treatment of diabetic retinopathy

(2016) Michael Steven Tolentino et al.   EXPERT OPINION ON INVESTIGATIONAL DRUGS

C-peptide protects against hyperglycemic memory and vascular endothelial cell apoptosis

(2016) Mahendra Prasad Bhatt et al.   JOURNAL OF ENDOCRINOLOGY

Therapeutic advances in Huntington's Disease

(2015) Kathleen M. Shannon et al.   MOVEMENT DISORDERS

Cystamine/cysteamine rescues the dopaminergic system and shows neurorestorative properties in an animal model of Parkinson's disease

(2015) G. Cisbani et al.   NEUROBIOLOGY OF DISEASE

Restoration of CFTR function in patients with cystic fibrosis carrying the F508del-CFTR mutation

(2014) Daniela De Stefano et al.   Autophagy

C-peptide replacement therapy as an emerging strategy for preventing diabetic vasculopathy

(2014) M. P. Bhatt et al.   CARDIOVASCULAR RESEARCH

Activation of the Nrf2/HO-1 Antioxidant Pathway Contributes to the Protective Effects of Lycium Barbarum Polysaccharides in the Rodent Retina after Ischemia-Reperfusion-Induced Damage

(2014) Meihua He et al.   PLoS One

Cysteamine, a pro-BDNF drug, as an adjunctive treatment for schizophrenia

(2014) Peter F. Buckley et al.   SCHIZOPHRENIA RESEARCH

Prevention of VEGF-mediated microvascular permeability by C-peptide in diabetic mice

(2013) Y.-C. Lim et al.   CARDIOVASCULAR RESEARCH

Cysteamine: an old drug with new potential

(2013) Martine Besouw et al.   DRUG DISCOVERY TODAY

Transglutaminase is a Therapeutic Target for Oxidative Stress, Excitotoxicity and Stroke: A new Epigenetic Kid on the Cns Block

(2013) Manuela Basso et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Novel Targets Against Retinal Angiogenesis in Diabetic Retinopathy

(2012) Shuang Wang et al.   Current Diabetes Reports

C-Peptide Prevents Hyperglycemia-Induced Endothelial Apoptosis Through Inhibition of Reactive Oxygen Species–Mediated Transglutaminase 2 Activation

(2012) Mahendra Prasad Bhatt et al.   DIABETES

Transglutaminase-mediated transamidation of serotonin, dopamine and noradrenaline to fibronectin: Evidence for a general mechanism of monoaminylation

(2012) René Hummerich et al.   FEBS LETTERS

Vitronectin Increases Vascular Permeability by Promoting VE-Cadherin Internalization at Cell Junctions

(2012) Rong Li et al.   PLoS One

Enteric-coated cysteamine for the treatment of paediatric non-alcoholic fatty liver disease

(2011) R. Dohil et al.   ALIMENTARY PHARMACOLOGY & THERAPEUTICS

Cysteamine restores glutathione redox status in cultured cystinotic proximal tubular epithelial cells

(2011) Martijn J. Wilmer et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Transglutaminase 2: a multi-functional protein in multiple subcellular compartments

(2010) Donghyun Park et al.   AMINO ACIDS

Role of GTPases in control of microvascular permeability

(2010) V. Spindler et al.   CARDIOVASCULAR RESEARCH

Potential of cystamine and cysteamine in the treatment of neurodegenerative diseases

(2010) C. Gibrat et al.   PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY