Macrophage 11β-HSD-1 deficiency promotes inflammatory angiogenesis

Tissue-specific contribution of macrophages to wound healing

(2017) Carlos M. Minutti et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

A Reservoir of Mature Cavity Macrophages that Can Rapidly Invade Visceral Organs to Affect Tissue Repair

(2016) Jing Wang et al.   CELL

11β-Hydroxysteroid Dehydrogenase Type 1 Is Expressed in Neutrophils and Restrains an Inflammatory Response in Male Mice

(2016) Agnes E. Coutinho et al.   ENDOCRINOLOGY

Nonclassical Ly6C− Monocytes Drive the Development of Inflammatory Arthritis in Mice

(2014) Alexander V. Misharin et al.   Cell Reports

11β-hydroxysteroid dehydrogenase type 1 deficiency in bone marrow-derived cells reduces atherosclerosis

(2013) Tiina Kipari et al.   FASEB JOURNAL

Identification of a Tissue-Specific, C/EBP -Dependent Pathway of Differentiation for Murine Peritoneal Macrophages

(2013) D. W. Cain et al.   JOURNAL OF IMMUNOLOGY

Changing glucocorticoid action: 11β-Hydroxysteroid dehydrogenase type 1 in acute and chronic inflammation

(2013) Karen E. Chapman et al.   JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY

Tissue-resident macrophages

(2013) Luke C Davies et al.   NATURE IMMUNOLOGY

11β-Hydroxysteroid Dehydrogenases: Intracellular Gate-Keepers of Tissue Glucocorticoid Action

(2013) Karen Chapman et al.   PHYSIOLOGICAL REVIEWS

11β-Hydroxysteroid Dehydrogenase Type 1 Gene Knockout Attenuates Atherosclerosis and In Vivo Foam Cell Formation in Hyperlipidemic apoE−/− Mice

(2013) Ricardo A. García et al.   PLoS One

Blockade of the hedgehog pathway inhibits osteophyte formation in arthritis

(2012) Gisela Ruiz-Heiland et al.   ANNALS OF THE RHEUMATIC DISEASES

12/15-Lipoxygenase Orchestrates the Clearance of Apoptotic Cells and Maintains Immunologic Tolerance

(2012) Stefan Uderhardt et al.   IMMUNITY

11β-HSD1 inhibition reduces atherosclerosis in mice by altering proinflammatory gene expression in the vasculature

(2012) Mingjuan J. Luo et al.   PHYSIOLOGICAL GENOMICS

Peroxisome Proliferator–Activated Receptor-γ Activation Induces 11β-Hydroxysteroid Dehydrogenase Type 1 Activity in Human Alternative Macrophages

(2011) Giulia Chinetti-Gbaguidi et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

11β-Hydroxysteroid Dehydrogenase Type 1, But Not Type 2, Deficiency Worsens Acute Inflammation and Experimental Arthritis in Mice

(2011) Agnes E. Coutinho et al.   ENDOCRINOLOGY

The interplay between macrophages and angiogenesis in development, tissue injury and regeneration

(2011) Silvia Nucera et al.   INTERNATIONAL JOURNAL OF DEVELOPMENTAL BIOLOGY

Increased Angiogenesis Protects against Adipose Hypoxia and Fibrosis in Metabolic Disease-resistant 11β-Hydroxysteroid Dehydrogenase Type 1 (HSD1)-deficient Mice

(2011) Zoi Michailidou et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Tissue macrophages act as cellular chaperones for vascular anastomosis downstream of VEGF-mediated endothelial tip cell induction

(2010) A. Fantin et al.   BLOOD

Improved heart function follows enhanced inflammatory cell recruitment and angiogenesis in 11βHSD1-deficient mice post-MI

(2010) Sara J. McSweeney et al.   CARDIOVASCULAR RESEARCH

Applications of myeloid-specific promoters in transgenic mice support in vivo imaging and functional genomics but do not support the concept of distinct macrophage and dendritic cell lineages or roles in immunity

(2010) D. A. Hume   JOURNAL OF LEUKOCYTE BIOLOGY

The anti-inflammatory and immunosuppressive effects of glucocorticoids, recent developments and mechanistic insights

(2010) Agnes E. Coutinho et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Preadipocyte 11β-Hydroxysteroid Dehydrogenase Type 1 Is a Keto-Reductase and Contributes to Diet-Induced Visceral Obesityin Vivo

(2008) R. A. De Sousa Peixoto et al.   ENDOCRINOLOGY