Mid-life environmental enrichment increases synaptic density in CA1 in a mouse model of Aβ-associated pathology and positively influences synaptic and cognitive health in healthy ageing

Sending your grandparents to university increases cognitive reserve: The Tasmanian Healthy Brain Project.

(2016) Megan E. Lenehan et al.   NEUROPSYCHOLOGY

The effect of focal brain injury on beta-amyloid plaque deposition, inflammation and synapses in the APP/PS1 mouse model of Alzheimer's disease

(2015) Jessica M. Collins et al.   EXPERIMENTAL NEUROLOGY

BDNF contributes to the facilitation of hippocampal synaptic plasticity and learning enabled by environmental enrichment

(2014) Tanja Novkovic et al.   HIPPOCAMPUS

Changes in the brain and plasma Aβ peptide levels with age and its relationship with cognitive impairment in the APPswe/PS1dE9 mouse model of Alzheimer’s disease

(2014) M. Izco et al.   NEUROSCIENCE

Relationship between education and age-related cognitive decline: a review of recent research

(2014) Megan Elizabeth Lenehan et al.   Psychogeriatrics

Synaptic Health

(2014) John H. Morrison et al.   JAMA Psychiatry

Short-term environmental enrichment, in the absence of exercise, improves memory, and increases NGF concentration, early neuronal survival, and synaptogenesis in the dentate gyrus in a time-dependent manner

(2013) Amy M. Birch et al.   HIPPOCAMPUS

BDNF-based synaptic repair as a disease-modifying strategy for neurodegenerative diseases

(2013) Bai Lu et al.   NATURE REVIEWS NEUROSCIENCE

Altered synapses and gliotransmission in Alzheimer's disease and AD model mice

(2013) Stanislaw Mitew et al.   NEUROBIOLOGY OF AGING

Environmental enrichment induces neuroplastic changes in middle age female BalbC mice and increases the hippocampal levels of BDNF, p-Akt and p-MAPK1/2

(2013) G. Ramírez-Rodríguez et al.   NEUROSCIENCE

Neurites containing the neurofilament-triplet proteins are selectively vulnerable to cytoskeletal pathology in Alzheimer’s disease and transgenic mouse models

(2013) Stanislaw Mitew et al.   Frontiers in Neuroanatomy

Enhanced Antigen Retrieval of Amyloid β Immunohistochemistry

(2012) Hideaki Kai et al.   JOURNAL OF HISTOCHEMISTRY & CYTOCHEMISTRY

Intraneuronal Aβ detection in 5xFAD mice by a new Aβ-specific antibody

(2012) Katherine L Youmans et al.   Molecular Neurodegeneration

Neurotrophin regulation of neural circuit development and function

(2012) Hyungju Park et al.   NATURE REVIEWS NEUROSCIENCE

Transient enriched housing before amyloidosis onset sustains cognitive improvement in Tg2576 mice

(2012) Laure Verret et al.   NEUROBIOLOGY OF AGING

Brain-Derived Neurotrophic Factor: A Dynamic Gatekeeper of Neural Plasticity

(2012) Kiriana Cowansage et al.   Current Molecular Pharmacology

Cognitive Lifestyle and Long-Term Risk of Dementia and Survival After Diagnosis in a Multicenter Population-based Cohort

(2011) M. Valenzuela et al.   AMERICAN JOURNAL OF EPIDEMIOLOGY

Amyloid Generation and Dysfunctional Immunoproteasome Activation with Disease Progression in Animal Model of Familial Alzheimer's Disease

(2011) Ester Aso et al.   BRAIN PATHOLOGY

Development and distribution of neuronal cilia in mouse neocortex

(2011) Jon I. Arellano et al.   JOURNAL OF COMPARATIVE NEUROLOGY

Enhanced intrinsic excitability and EPSP-spike coupling accompany enriched environment-induced facilitation of LTP in hippocampal CA1 pyramidal neurons

(2011) Ruchi Malik et al.   JOURNAL OF NEUROPHYSIOLOGY

Preventive and therapeutic types of environmental enrichment counteract beta amyloid pathology by different molecular mechanisms

(2011) Arne Herring et al.   NEUROBIOLOGY OF DISEASE

How Inhibition Shapes Cortical Activity

(2011) Jeffry S. Isaacson et al.   NEURON

The pathological process underlying Alzheimer’s disease in individuals under thirty

(2010) Heiko Braak et al.   ACTA NEUROPATHOLOGICA

Frequency-dependent changes in synaptic plasticity and brain-derived neurotrophic factor (BDNF) expression in the CA1 to perirhinal cortex projection

(2010) John Kealy et al.   BRAIN RESEARCH

Cytoarchitectonic and chemoarchitectonic characterization of the prefrontal cortical areas in the mouse

(2010) H. J. J. M. Van De Werd et al.   Brain Structure & Function

Layer-specific alterations to CA1 dendritic spines in a mouse model of Alzheimer's disease

(2010) P. Merino-Serrais et al.   HIPPOCAMPUS

DHHC5 Interacts with PDZ Domain 3 of Post-synaptic Density-95 (PSD-95) Protein and Plays a Role in Learning and Memory

(2010) Yi Li et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Synaptic proteins are tonotopically graded in postnatal and adult type I and type II spiral ganglion neurons

(2010) Jacqueline Flores-Otero et al.   JOURNAL OF COMPARATIVE NEUROLOGY

Amyloid-β–induced neuronal dysfunction in Alzheimer's disease: from synapses toward neural networks

(2010) Jorge J Palop et al.   NATURE NEUROSCIENCE

Environmental enrichment fails to rescue working memory deficits, neuron loss, and neurogenesis in APP/PS1KI mice

(2010) Marie-Caroline Cotel et al.   NEUROBIOLOGY OF AGING

Axonopathy and cytoskeletal disruption in degenerative diseases of the central nervous system

(2009) James C. Vickers et al.   BRAIN RESEARCH BULLETIN

Network Dynamics Underlying the Formation of Sparse, Informative Representations in the Hippocampus

(2008) M. P. Karlsson et al.   JOURNAL OF NEUROSCIENCE

Synaptic contact number and size in stratum radiatum CA1 of APP/PS1ΔE9 transgenic mice

(2008) Mark J. West et al.   NEUROBIOLOGY OF AGING