Modeling on-column reduction of trisulfide bonds in monoclonal antibodies during protein A chromatography

标题
Modeling on-column reduction of trisulfide bonds in monoclonal antibodies during protein A chromatography
作者
关键词
Monoclonal antibodies, Trisulfides, Product heterogeneity, Protein A chromatography, Cysteine wash, Model
出版物
JOURNAL OF CHROMATOGRAPHY A
Volume 1479, Issue -, Pages 81-86
出版商
Elsevier BV
发表日期
2016-11-15
DOI
10.1016/j.chroma.2016.11.019

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