Vimentin intermediate filaments control actin stress fiber assembly through GEF-H1 and RhoA

Interplay between Solo and keratin filaments is crucial for mechanical force–induced stress fiber reinforcement

(2016) Sachiko Fujiwara et al.   MOLECULAR BIOLOGY OF THE CELL

Cytoskeletal crosstalk: when three different personalities team up

(2015) Florian Huber et al.   CURRENT OPINION IN CELL BIOLOGY

Intermediate filaments in cell migration and invasion: the unusual suspects

(2015) Cécile Leduc et al.   CURRENT OPINION IN CELL BIOLOGY

Regulation of keratin network organization

(2015) Fanny Loschke et al.   CURRENT OPINION IN CELL BIOLOGY

Cellular chirality arising from the self-organization of the actin cytoskeleton

(2015) Yee Han Tee et al.   NATURE CELL BIOLOGY

Inverted formin 2 in focal adhesions promotes dorsal stress fiber and fibrillar adhesion formation to drive extracellular matrix assembly

(2015) Colleen T. Skau et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

RalB regulates contractility-driven cancer dissemination upon TGFβ stimulation via the RhoGEF GEF-H1

(2015) Marco Biondini et al.   Scientific Reports

Bidirectional Interplay between Vimentin Intermediate Filaments and Contractile Actin Stress Fibers

(2015) Yaming Jiu et al.   Cell Reports

Interaction between the Type III Effector VopO and GEF-H1 Activates the RhoA-ROCK Pathway

(2015) Hirotaka Hiyoshi et al.   PLoS Pathogens

Generation of contractile actomyosin bundles depends on mechanosensitive actin filament assembly and disassembly

(2015) Sari Tojkander et al.   eLife

Vimentin Enhances Cell Elastic Behavior and Protects against Compressive Stress

(2014) M.G. Mendez et al.   BIOPHYSICAL JOURNAL

The RhoGEF GEF-H1 Is Required for Oncogenic RAS Signaling via KSR-1

(2014) Jane Cullis et al.   CANCER CELL

A systematic nomenclature for mammalian tropomyosin isoforms

(2014) Michael A. Geeves et al.   JOURNAL OF MUSCLE RESEARCH AND CELL MOTILITY

Post-translational modifications of intermediate filament proteins: mechanisms and functions

(2014) Natasha T. Snider et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Vimentin regulates lung cancer cell adhesion through a VAV2–Rac1 pathway to control focal adhesion kinase activity

(2014) L S Havel et al.   ONCOGENE

Mechanosensing through focal adhesion-anchored intermediate filaments

(2013) Martin Gregor et al.   FASEB JOURNAL

The tension mounts: Stress fibers as force-generating mechanotransducers

(2013) Keith Burridge et al.   JOURNAL OF CELL BIOLOGY

Extracellular Signal-Regulated Kinase Regulates RhoA Activation and Tumor Cell Plasticity by Inhibiting Guanine Exchange Factor H1 Activity

(2013) Anne von Thun et al.   MOLECULAR AND CELLULAR BIOLOGY

Improved throughput traction microscopy reveals pivotal role for matrix stiffness in fibroblast contractility and TGF-β responsiveness

(2012) Aleksandar Marinković et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

From Mechanical Force to RhoA Activation

(2012) Elizabeth C. Lessey et al.   BIOCHEMISTRY

Changes in Ect2 Localization Couple Actomyosin-Dependent Cell Shape Changes to Mitotic Progression

(2012) Helen K. Matthews et al.   DEVELOPMENTAL CELL

The Microtubule-Associated Rho Activating Factor GEF-H1 Interacts with Exocyst Complex to Regulate Vesicle Traffic

(2012) Ritu Pathak et al.   DEVELOPMENTAL CELL

Actin stress fibers - assembly, dynamics and biological roles

(2012) S. Tojkander et al.   JOURNAL OF CELL SCIENCE

GEF-H1 over-expression in hepatocellular carcinoma promotes cell motility via activation of RhoA signalling

(2012) Ibis KC Cheng et al.   JOURNAL OF PATHOLOGY

Actin retrograde flow and actomyosin II arc contraction drive receptor cluster dynamics at the immunological synapse in Jurkat T cells

(2012) Jason Yi et al.   MOLECULAR BIOLOGY OF THE CELL

A Molecular Pathway for Myosin II Recruitment to Stress Fibers

(2011) Sari Tojkander et al.   CURRENT BIOLOGY

Polarity-regulating Kinase Partitioning-defective 1b (PAR1b) Phosphorylates Guanine Nucleotide Exchange Factor H1 (GEF-H1) to Regulate RhoA-dependent Actin Cytoskeletal Reorganization

(2011) Yukie Yamahashi et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Cytoplasmic intermediate filaments mediate actin-driven positioning of the nucleus

(2011) I. Dupin et al.   JOURNAL OF CELL SCIENCE

A role for actin arcs in the leading-edge advance of migrating cells

(2011) Dylan T. Burnette et al.   NATURE CELL BIOLOGY

The Rho GEFs LARG and GEF-H1 regulate the mechanical response to force on integrins

(2011) Christophe Guilluy et al.   NATURE CELL BIOLOGY

Analysis of RhoA and Rho GEF activity in whole cells and the cell nucleus

(2011) Christophe Guilluy et al.   Nature Protocols

Vimentin induces changes in cell shape, motility, and adhesion during the epithelial to mesenchymal transition

(2010) Melissa G. Mendez et al.   FASEB JOURNAL

Recruitment of vimentin to the cell surface by  3 integrin and plectin mediates adhesion strength

(2009) R. Bhattacharya et al.   JOURNAL OF CELL SCIENCE

Introducing intermediate filaments: from discovery to disease

(2009) John E. Eriksson et al.   JOURNAL OF CLINICAL INVESTIGATION

Vimentin Coil 1A—A Molecular Switch Involved in the Initiation of Filament Elongation

(2009) Markus Meier et al.   JOURNAL OF MOLECULAR BIOLOGY

Guanine Nucleotide Exchange Factor-H1 Regulates Cell Migration via Localized Activation of RhoA at the Leading Edge

(2009) Perihan Nalbant et al.   MOLECULAR BIOLOGY OF THE CELL

Reinforcement versus Fluidization in Cytoskeletal Mechanoresponsiveness

(2009) Ramaswamy Krishnan et al.   PLoS One

ERK1/2 phosphorylate GEF-H1 to enhance its guanine nucleotide exchange activity toward RhoA

(2008) Shuh-hei Fujishiro et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Mammalian Rho GTPases: new insights into their functions from in vivo studies

(2008) Sarah J. Heasman et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY