Cherubism Mice Also Deficient in c-Fos Exhibit Inflammatory Bone Destruction Executed by Macrophages That Express MMP14 Despite the Absence of TRAP+ Osteoclasts

Selective Inhibition of Membrane Type 1 Matrix Metalloproteinase Abrogates Progression of Experimental Inflammatory Arthritis: Synergy With Tumor Necrosis Factor Blockade

(2016) Kazuyo Kaneko et al.   Arthritis & Rheumatology

Effect of denosumab on Japanese patients with rheumatoid arthritis: a dose–response study of AMG 162 (Denosumab) in patients withRheumatoId arthritis on methotrexate toValidate inhibitory effect on boneErosion (DRIVE)—a 12-month, multicentre, randomised, double-blind, placebo-controlled, phase II clinical trial

(2015) Tsutomu Takeuchi et al.   ANNALS OF THE RHEUMATIC DISEASES

Giant cell tumour of bone: new treatments in development

(2015) A. López-Pousa et al.   Clinical & Translational Oncology

Viewpoints on vessels and vanishing bones in Gorham–Stout disease

(2014) Michael T. Dellinger et al.   BONE

SH3BP2 Cherubism Mutation Potentiates TNF-α-Induced Osteoclastogenesis via NFATc1 and TNF-α-Mediated Inflammatory Bone Loss

(2014) Tomoyuki Mukai et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Rheumatoid arthritis associated with osteopetrosis

(2014) Yuho Kadono et al.   Modern Rheumatology

Enhanced TLR-MYD88 Signaling Stimulates Autoinflammation in SH3BP2 Cherubism Mice and Defines the Etiology of Cherubism

(2014) Teruhito Yoshitaka et al.   Cell Reports

Osteopetrosis: genetics, treatment and new insights into osteoclast function

(2013) Cristina Sobacchi et al.   Nature Reviews Endocrinology

Forced expression of stabilized c-Fos in dendritic cells reduces cytokine production and immune responses in vivo

(2012) Ryoko Yoshida et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Anti-tumor necrosis factor treatment in cherubism — Clinical, radiological and histological findings in two children

(2012) M. Hero et al.   BONE

Novel MT1-MMP Small-Molecule Inhibitors Based on Insights into Hemopexin Domain Function in Tumor Growth

(2012) A. G. Remacle et al.   CANCER RESEARCH

Demonstration of osteocytic perilacunar/canalicular remodeling in mice during lactation

(2012) Hai Qing et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Bone erosion in rheumatoid arthritis: mechanisms, diagnosis and treatment

(2012) Georg Schett et al.   Nature Reviews Rheumatology

Loss of Tankyrase-Mediated Destruction of 3BP2 Is the Underlying Pathogenic Mechanism of Cherubism

(2011) Noam Levaot et al.   CELL

Pro416Arg cherubism mutation in Sh3bp2 knock-in mice affects osteoblasts and alters bone mineral and matrix properties

(2010) Chiachien J. Wang et al.   BONE

Membrane-Type I Matrix Metalloproteinase-Dependent Regulation of Rheumatoid Arthritis Synoviocyte Function

(2010) F. Sabeh et al.   JOURNAL OF IMMUNOLOGY

Membrane type 1 matrix metalloproteinase is a crucial promoter of synovial invasion in human rheumatoid arthritis

(2009) Mary-Clare Miller et al.   ARTHRITIS AND RHEUMATISM

Selective Inhibition of Matrix Metalloproteinase-14 Blocks Tumor Growth, Invasion, and Angiogenesis

(2009) Laetitia Devy et al.   CANCER RESEARCH

Bone remodeling in rheumatic disease: a question of balance

(2009) Nicole C. Walsh et al.   IMMUNOLOGICAL REVIEWS

Osteoimmunology and the effects of the immune system on bone

(2009) Hiroshi Takayanagi   Nature Reviews Rheumatology

Bone-Resorbing Cells in Multiple Myeloma: Osteoclasts, Myeloma Cell Polykaryons, or Both?

(2009) F. Silvestris et al.   ONCOLOGIST

Treatment options in patients with rheumatoid arthritis failing initial TNF inhibitor therapy: a critical review

(2009) Andrea Rubbert-Roth et al.   ARTHRITIS RESEARCH & THERAPY

NFATc1 in mice represses osteoprotegerin during osteoclastogenesis and dissociates systemic osteopenia from inflammation in cherubism

(2008) Antonios O. Aliprantis et al.   JOURNAL OF CLINICAL INVESTIGATION