SH3BP2 Cherubism Mutation Potentiates TNF-α-Induced Osteoclastogenesis via NFATc1 and TNF-α-Mediated Inflammatory Bone Loss

Tyrosine phosphorylation of 3BP2 is indispensable for the interaction with VAV3 in chicken DT40 cells

(2014) Kazuyasu Chihara et al.   EXPERIMENTAL CELL RESEARCH

Etanercept Administration to Neonatal SH3BP2 Knock-In Cherubism Mice Prevents TNF-α-Induced Inflammation and Bone Loss

(2013) Teruhito Yoshitaka et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Anti-tumor necrosis factor treatment in cherubism — Clinical, radiological and histological findings in two children

(2012) M. Hero et al.   BONE

Standardized nomenclature, symbols, and units for bone histomorphometry: A 2012 update of the report of the ASBMR Histomorphometry Nomenclature Committee

(2012) David W Dempster et al.   JOURNAL OF BONE AND MINERAL RESEARCH

TNF-induced osteoclastogenesis and inflammatory bone resorption are inhibited by transcription factor RBP-J

(2012) Baohong Zhao et al.   JOURNAL OF EXPERIMENTAL MEDICINE

The Adaptor 3BP2 Is Required for Early and Late Events in Fc RI Signaling in Human Mast Cells

(2012) E. Ainsua-Enrich et al.   JOURNAL OF IMMUNOLOGY

Inflammatory bone loss: pathogenesis and therapeutic intervention

(2012) Kurt Redlich et al.   NATURE REVIEWS DRUG DISCOVERY

Loss of Tankyrase-Mediated Destruction of 3BP2 Is the Underlying Pathogenic Mechanism of Cherubism

(2011) Noam Levaot et al.   CELL

Structural Basis and Sequence Rules for Substrate Recognition by Tankyrase Explain the Basis for Cherubism Disease

(2011) Sebastian Guettler et al.   CELL

Association of 3BP2 with SHP-1 regulates SHP-1-mediated production of TNF-α in RBL-2H3 cells

(2011) Kazuyasu Chihara et al.   GENES TO CELLS

Osteopontin Signals through Calcium and Nuclear Factor of Activated T Cells (NFAT) in Osteoclasts

(2011) Natsuko Tanabe et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

3BP2-deficient mice are osteoporotic with impaired osteoblast and osteoclast functions

(2011) Noam Levaot et al.   JOURNAL OF CLINICAL INVESTIGATION

TNF activates calcium-nuclear factor of activated T cells (NFAT)c1 signaling pathways in human macrophages

(2011) A. Yarilina et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

3BP2 Adapter Protein Is Required for Receptor Activator of NFκB Ligand (RANKL)-induced Osteoclast Differentiation of RAW264.7 Cells

(2010) Amel GuezGuez et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Guidelines for assessment of bone microstructure in rodents using micro-computed tomography

(2010) Mary L Bouxsein et al.   JOURNAL OF BONE AND MINERAL RESEARCH

The Blimp1–Bcl6 axis is critical to regulate osteoclast differentiation and bone homeostasis

(2010) Yoshiteru Miyauchi et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Blimp1-mediated repression of negative regulators is required for osteoclast differentiation

(2010) K. Nishikawa et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Ca2+-NFATc1 signaling is an essential axis of osteoclast differentiation

(2009) Takako Negishi-Koga et al.   IMMUNOLOGICAL REVIEWS

Tyrosine Phosphorylation of 3BP2 Regulates B Cell Receptor-mediated Activation of NFAT

(2009) Upasana Shukla et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

NF-κB p100 limits TNF-induced bone resorption in mice by a TRAF3-dependent mechanism

(2009) Zhenqiang Yao et al.   JOURNAL OF CLINICAL INVESTIGATION

Bone loss in inflammatory disorders

(2009) R Hardy et al.   JOURNAL OF ENDOCRINOLOGY

Interferon regulatory factor-8 regulates bone metabolism by suppressing osteoclastogenesis

(2009) Baohong Zhao et al.   NATURE MEDICINE

NFATc1 in mice represses osteoprotegerin during osteoclastogenesis and dissociates systemic osteopenia from inflammation in cherubism

(2008) Antonios O. Aliprantis et al.   JOURNAL OF CLINICAL INVESTIGATION