Probing conformational dynamics in biomolecules via chemical exchange saturation transfer: a primer

Separating Dipolar and Chemical Exchange Magnetization Transfer Processes in 1 H-CEST

(2016) Tairan Yuwen et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Rapid Determination of Fast Protein Dynamics from NMR Chemical Exchange Saturation Transfer Data

(2016) Yina Gu et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

A protocol for the refinement of NMR structures using simultaneously pseudocontact shift restraints from multiple lanthanide ions

(2016) Davide Sala et al.   JOURNAL OF BIOMOLECULAR NMR

High-power 1 H composite pulse decoupling provides artifact free exchange-mediated saturation transfer (EST) experiments

(2016) Kalyan S. Chakrabarti et al.   JOURNAL OF MAGNETIC RESONANCE

Determination of pseudocontact shifts of low-populated excited states by NMR chemical exchange saturation transfer

(2016) R. S. Ma et al.   PHYSICAL CHEMISTRY CHEMICAL PHYSICS

Hsp70 biases the folding pathways of client proteins

(2016) Ashok Sekhar et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Transient HIV-1 Gag–protease interactions revealed by paramagnetic NMR suggest origins of compensatory drug resistance mutations

(2016) Lalit Deshmukh et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Visualizing the formation of an RNA folding intermediate through a fast highly modular secondary structure switch

(2016) Yi Xue et al.   Nature Communications

Probing Invisible, Excited Protein States by Non-Uniformly Sampled Pseudo-4D CEST Spectroscopy

(2015) Dong Long et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Speeding-up exchange-mediated saturation transfer experiments by Fourier transform

(2015) Marta G. Carneiro et al.   JOURNAL OF BIOMOLECULAR NMR

13CHD2–CEST NMR spectroscopy provides an avenue for studies of conformational exchange in high molecular weight proteins

(2015) Enrico Rennella et al.   JOURNAL OF BIOMOLECULAR NMR

Measuring Residual Dipolar Couplings in Excited Conformational States of Nucleic Acids by CEST NMR Spectroscopy

(2015) Bo Zhao et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Mapping the conformation of a client protein through the Hsp70 functional cycle

(2015) Ashok Sekhar et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Thermal fluctuations of immature SOD1 lead to separate folding and misfolding pathways

(2015) Ashok Sekhar et al.   eLife

An Off-Pathway Folding Intermediate of an Acyl Carrier Protein Domain Coexists with the Folded and Unfolded States under Native Conditions

(2014) Jackwee Lim et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Characterizing Methyl-Bearing Side Chain Contacts and Dynamics Mediating Amyloid β Protofibril Interactions Using13Cmethyl-DEST and Lifetime Line Broadening

(2014) Nicolas L. Fawzi et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Bringing Dynamic Molecular Machines into Focus by Methyl-TROSY NMR

(2014) Rina Rosenzweig et al.   Annual Review of Biochemistry

Triple resonance-based 13Cα and 13Cβ CEST experiments for studies of ms timescale dynamics in proteins

(2014) Dong Long et al.   JOURNAL OF BIOMOLECULAR NMR

Chemical exchange in biomacromolecules: Past, present, and future

(2014) Arthur G. Palmer   JOURNAL OF MAGNETIC RESONANCE

Effects of J couplings and unobservable minor states on kinetics parameters extracted from CEST data

(2014) Yang Zhou et al.   JOURNAL OF MAGNETIC RESONANCE

Measurement of histidine pKa values and tautomer populations in invisible protein states

(2014) A. L. Hansen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Measuring hydrogen exchange rates in invisible protein excited states

(2014) D. Long et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Probing Slow Chemical Exchange at Carbonyl Sites in Proteins by Chemical Exchange Saturation Transfer NMR Spectroscopy

(2013) Pramodh Vallurupalli et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

A Computational Study of the Effects of13C-13C Scalar Couplings on13C CEST NMR Spectra: Towards Studies on a Uniformly13C-Labeled Protein

(2013) Pramodh Vallurupalli et al.   CHEMBIOCHEM

Structure determination of protein–protein complexes with long-range anisotropic paramagnetic NMR restraints

(2013) Mathias AS Hass et al.   CURRENT OPINION IN STRUCTURAL BIOLOGY

Visualizing Side Chains of Invisible Protein Conformers by Solution NMR

(2013) Guillaume Bouvignies et al.   JOURNAL OF MOLECULAR BIOLOGY

Characterizing Slow Chemical Exchange in Nucleic Acids by Carbon CEST and Low Spin-Lock Field R1ρ NMR Spectroscopy

(2013) Bo Zhao et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

A 13C Labeling Strategy Reveals a Range of Aromatic Side Chain Motion in Calmodulin

(2013) Vignesh Kasinath et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Chemical exchange saturation transfer (CEST) and MRZ-spectroscopyin vivo: a review of theoretical approaches and methods

(2013) Moritz Zaiss et al.   PHYSICS IN MEDICINE AND BIOLOGY

NMR paves the way for atomic level descriptions of sparsely populated, transiently formed biomolecular conformers

(2013) A. Sekhar et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Probing the transient dark state of substrate binding to GroEL by relaxation-based solution NMR

(2013) D. S. Libich et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A 2D 13C-CEST experiment for studying slowly exchanging protein systems using methyl probes: an application to protein folding

(2012) Guillaume Bouvignies et al.   JOURNAL OF BIOMOLECULAR NMR

Protein Structure Determination from Pseudocontact Shifts Using ROSETTA

(2012) Christophe Schmitz et al.   JOURNAL OF MOLECULAR BIOLOGY

Measurement of Proton Chemical Shifts in Invisible States of Slowly Exchanging Protein Systems by Chemical Exchange Saturation Transfer

(2012) Guillaume Bouvignies et al.   JOURNAL OF PHYSICAL CHEMISTRY B

Studying “Invisible” Excited Protein States in Slow Exchange with a Major State Conformation

(2012) Pramodh Vallurupalli et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Structure of an Intermediate State in Protein Folding and Aggregation

(2012) P. Neudecker et al.   SCIENCE

Using the water signal to detect invisible exchanging protons in the catalytic triad of a serine protease

(2011) Carolyn B. Lauzon et al.   JOURNAL OF BIOMOLECULAR NMR

Increasing the Exchange Time-Scale That Can Be Probed by CPMG Relaxation Dispersion NMR

(2011) Pramodh Vallurupalli et al.   JOURNAL OF PHYSICAL CHEMISTRY B

Chemical exchange saturation transfer (CEST): What is in a name and what isn't?

(2011) Peter C. M. van Zijl et al.   MAGNETIC RESONANCE IN MEDICINE

Solution structure of a minor and transiently formed state of a T4 lysozyme mutant

(2011) Guillaume Bouvignies et al.   NATURE

Atomic-resolution dynamics on the surface of amyloid-β protofibrils probed by solution NMR

(2011) Nicolas L. Fawzi et al.   NATURE

Molecular chaperones in protein folding and proteostasis

(2011) F. Ulrich Hartl et al.   NATURE

Analysis of non-uniformly sampled spectra with multi-dimensional decomposition

(2011) Vladislav Yu. Orekhov et al.   PROGRESS IN NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY

Rapid Three-Dimensional MAS NMR Spectroscopy at Critical Sensitivity

(2010) Yoh Matsuki et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Iterative algorithm of discrete Fourier transform for processing randomly sampled NMR data sets

(2010) Jan Stanek et al.   JOURNAL OF BIOMOLECULAR NMR

Kinetics of Amyloid β Monomer-to-Oligomer Exchange by NMR Relaxation

(2010) Nicolas L. Fawzi et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Alzheimer's Disease

(2010) Henry W. Querfurth et al.   NEW ENGLAND JOURNAL OF MEDICINE

Protein folding dynamics: The diffusion-collision model and experimental data

(2010) Martin Karplus et al.   PROTEIN SCIENCE

Tautomeric states of the active-site histidines of phosphorylated and unphosphorylated IIIGlc, a signal-transducing protein from escherichia coli, using two-dimensional heteronuclear NMR techniques

(2010) J.G. Pelton et al.   PROTEIN SCIENCE

A Transient and Low-Populated Protein-Folding Intermediate at Atomic Resolution

(2010) Dmitry M. Korzhnev et al.   SCIENCE

Human Serum Albumin Inhibits Aβ Fibrillization through a “Monomer-Competitor” Mechanism

(2009) Julijana Milojevic et al.   BIOPHYSICAL JOURNAL

Importing Mitochondrial Proteins: Machineries and Mechanisms

(2009) Agnieszka Chacinska et al.   CELL

Theory, Practice, and Applications of Paramagnetic Relaxation Enhancement for the Characterization of Transient Low-Population States of Biological Macromolecules and Their Complexes

(2009) G. Marius Clore et al.   CHEMICAL REVIEWS

Measuring 13Cβ chemical shifts of invisible excited states in proteins by relaxation dispersion NMR spectroscopy

(2009) Patrik Lundström et al.   JOURNAL OF BIOMOLECULAR NMR

Spectroscopy by Integration of Frequency and Time Domain Information for Fast Acquisition of High-Resolution Dark Spectra

(2009) Yoh Matsuki et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Assignment of Ile, Leu, and Val Methyl Correlations in Supra-Molecular Systems: An Application to Aspartate Transcarbamoylase

(2009) Algirdas Velyvis et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Isotope labeling methods for studies of excited protein states by relaxation dispersion NMR spectroscopy

(2009) Patrik Lundström et al.   Nature Protocols

Measurement of carbonyl chemical shifts of excited protein states by relaxation dispersion NMR spectroscopy: comparison between uniformly and selectively 13C labeled samples

(2008) Patrik Lundström et al.   JOURNAL OF BIOMOLECULAR NMR

Quantifying Two-Bond1HN−13CO and One-Bond1Hα−13CαDipolar Couplings of Invisible Protein States by Spin-State Selective Relaxation Dispersion NMR Spectroscopy

(2008) D. Flemming Hansen et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Structures of invisible, excited protein states by relaxation dispersion NMR spectroscopy

(2008) P. Vallurupalli et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA