Control of autoimmune inflammation using liposomes to deliver positive allosteric modulators of metabotropic glutamate receptors

Impact of molecular weight on the intrinsic immunogenic activity of poly(beta amino esters)

(2017) James I. Andorko et al.   JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A

Design of Polyelectrolyte Multilayers to Promote Immunological Tolerance

(2016) Lisa H. Tostanoski et al.   ACS Nano

Intrinsic immunogenicity of rapidly-degradable polymers evolves during degradation

(2016) James I. Andorko et al.   Acta Biomaterialia

Delivery of siRNAs to Dendritic Cells Using DEC205-Targeted Lipid Nanoparticles to Inhibit Immune Responses

(2016) Joseph A Katakowski et al.   MOLECULAR THERAPY

Immunometabolism of regulatory T cells

(2016) Ryan Newton et al.   NATURE IMMUNOLOGY

Allosteric modulation of metabotropic glutamate receptor 4 activates IDO1-dependent, immunoregulatory signaling in dendritic cells

(2016) Claudia Volpi et al.   NEUROPHARMACOLOGY

CD206-Targeted Liposomal Myelin Basic Protein Peptides in Patients with Multiple Sclerosis Resistant to First-Line Disease-Modifying Therapies: A First-in-Human, Proof-of-Concept Dose-Escalation Study

(2016) Alexey Belogurov et al.   Neurotherapeutics

Tolerogenic nanoparticles inhibit T cell–mediated autoimmunity through SOCS2

(2016) Ada Yeste et al.   Science Signaling

Harnessing Nanoparticles for Immune Modulation

(2016) Daniel R. Getts et al.   TRENDS IN IMMUNOLOGY

Reprogramming the Local Lymph Node Microenvironment Promotes Tolerance that Is Systemic and Antigen Specific

(2016) Lisa H. Tostanoski et al.   Cell Reports

Tolerogenic nanoparticles inhibit T cell–mediated autoimmunity through SOCS2

(2016) Ada Yeste et al.   Science Signaling

CD5L/AIM Regulates Lipid Biosynthesis and Restrains Th17 Cell Pathogenicity

(2015) Chao Wang et al.   CELL

Metabolic reprogramming in macrophages and dendritic cells in innate immunity

(2015) Beth Kelly et al.   CELL RESEARCH

Immunometabolism: Cellular Metabolism Turns Immune Regulator

(2015) Róisín M. Loftus et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Nanoparticulate STING agonists are potent lymph node–targeted vaccine adjuvants

(2015) Melissa C. Hanson et al.   JOURNAL OF CLINICAL INVESTIGATION

Controlled delivery of a metabolic modulator promotes regulatory T cells and restrains autoimmunity

(2015) Joshua M. Gammon et al.   JOURNAL OF CONTROLLED RELEASE

Use of Autoantigen-Loaded Phosphatidylserine-Liposomes to Arrest Autoimmunity in Type 1 Diabetes

(2015) Irma Pujol-Autonell et al.   PLoS One

A combination hydrogel microparticle-based vaccine prevents type 1 diabetes in non-obese diabetic mice

(2015) Young Mee Yoon et al.   Scientific Reports

Nano-Drugs Based on Nano Sterically Stabilized Liposomes for the Treatment of Inflammatory Neurodegenerative Diseases

(2015) Keren Turjeman et al.   PLoS One

A Biodegradable Nanoparticle Platform for the Induction of Antigen-Specific Immune Tolerance for Treatment of Autoimmune Disease

(2014) Zoe Hunter et al.   ACS Nano

The role of CD22 and Siglec-G in B-cell tolerance and autoimmune disease

(2014) Jennifer Müller et al.   Nature Reviews Rheumatology

Cinnabarinic acid, an endogenous agonist of type-4 metabotropic glutamate receptor, suppresses experimental autoimmune encephalomyelitis in mice

(2014) Francesco Fazio et al.   NEUROPHARMACOLOGY

Polymeric synthetic nanoparticles for the induction of antigen-specific immunological tolerance

(2014) Roberto A. Maldonado et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Localized Immunotherapy via Liposome-Anchored Anti-CD137 + IL-2 Prevents Lethal Toxicity and Elicits Local and Systemic Antitumor Immunity

(2013) B. Kwong et al.   CANCER RESEARCH

Antigen-specific tolerization approaches in multiple sclerosis

(2013) Andreas Lutterotti et al.   EXPERT OPINION ON INVESTIGATIONAL DRUGS

Nanogel-based delivery of mycophenolic acid ameliorates systemic lupus erythematosus in mice

(2013) Michael Look et al.   JOURNAL OF CLINICAL INVESTIGATION

Copresentation of Antigen and Ligands of Siglec-G Induces B Cell Tolerance Independent of CD22

(2013) F. Pfrengle et al.   JOURNAL OF IMMUNOLOGY

Metabolism of inflammation limited by AMPK and pseudo-starvation

(2013) Luke A. J. O'Neill et al.   NATURE

Combinatorial delivery of immunosuppressive factors to dendritic cells using dual-sized microspheres

(2013) Jamal S. Lewis et al.   Journal of Materials Chemistry B

Microparticle surface modifications targeting dendritic cells for non-activating applications

(2012) Jamal S. Lewis et al.   BIOMATERIALS

Microparticles bearing encephalitogenic peptides induce T-cell tolerance and ameliorate experimental autoimmune encephalomyelitis

(2012) Daniel R Getts et al.   NATURE BIOTECHNOLOGY

Nanoparticle-mediated codelivery of myelin antigen and a tolerogenic small molecule suppresses experimental autoimmune encephalomyelitis

(2012) A. Yeste et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Induction of potent anti-tumor responses while eliminating systemic side effects via liposome-anchored combinatorial immunotherapy

(2011) Brandon Kwong et al.   BIOMATERIALS

Immunopathogenesis of multiple sclerosis

(2011) Manuel Comabella et al.   CLINICAL IMMUNOLOGY

Intracellular targeting delivery of liposomal drugs to solid tumors based on EPR effects

(2010) Kazuo Maruyama   ADVANCED DRUG DELIVERY REVIEWS

The Cystine/Glutamate Antiporter Regulates Dendritic Cell Differentiation and Antigen Presentation

(2010) J. A. D'Angelo et al.   JOURNAL OF IMMUNOLOGY

Glutamate joins the ranks of immunomodulators

(2010) Anna M Hansen et al.   NATURE MEDICINE

Metabotropic glutamate receptor-4 modulates adaptive immunity and restrains neuroinflammation

(2010) Francesca Fallarino et al.   NATURE MEDICINE

Chitin Is a Size-Dependent Regulator of Macrophage TNF and IL-10 Production

(2009) C. A. Da Silva et al.   JOURNAL OF IMMUNOLOGY

Dectin-1 directs T helper cell differentiation by controlling noncanonical NF-κB activation through Raf-1 and Syk

(2009) Sonja I Gringhuis et al.   NATURE IMMUNOLOGY

PEG Minocycline-Liposomes Ameliorate CNS Autoimmune Disease

(2009) Wei Hu et al.   PLoS One

Uptake of particulate vaccine adjuvants by dendritic cells activates the NALP3 inflammasome

(2009) Fiona A. Sharp et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Inflammasome-activating nanoparticles as modular systems for optimizing vaccine efficacy

(2009) Stacey L. Demento et al.   VACCINE

Delivery of rapamycin-loaded nanoparticle down regulates ICAM-1 expression and maintains an immunosuppressive profile in human CD34+ progenitor-derived dendritic cells

(2007) Saswati Das et al.   JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A