Timing the Microbes: The Circadian Rhythm of the Gut Microbiome

Interactions between the microbiota, immune and nervous systems in health and disease

(2017) Thomas C Fung et al.   NATURE NEUROSCIENCE

Timing the day: what makes bacterial clocks tick?

(2017) Carl Hirschie Johnson et al.   NATURE REVIEWS MICROBIOLOGY

Human and rat gut microbiome composition is maintained following sleep restriction

(2017) Shirley L. Zhang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Gut microbiota dysbiosis contributes to the development of hypertension

(2017) Jing Li et al.   Microbiome

Microbiota Diurnal Rhythmicity Programs Host Transcriptome Oscillations

(2016) Christoph A. Thaiss et al.   CELL

Gut Microbiota Regulate Motor Deficits and Neuroinflammation in a Model of Parkinson’s Disease

(2016) Timothy R. Sampson et al.   CELL

Gut Microbial Metabolite TMAO Enhances Platelet Hyperreactivity and Thrombosis Risk

(2016) Weifei Zhu et al.   CELL

High-Fiber Diet and Acetate Supplementation Change the Gut Microbiota and Prevent the Development of Hypertension and Heart Failure in Hypertensive MiceClinical Perspective

(2016) Francine Z. Marques et al.   CIRCULATION

Circadian Influence on Metabolism and Inflammation in Atherosclerosis

(2016) Cameron S. McAlpine et al.   CIRCULATION RESEARCH

Hypertension-Linked Pathophysiological Alterations in the GutNovelty and Significance

(2016) Monica M. Santisteban et al.   CIRCULATION RESEARCH

Analysis of factors contributing to variation in the C57BL/6J fecal microbiota across German animal facilities

(2016) Philipp Rausch et al.   INTERNATIONAL JOURNAL OF MEDICAL MICROBIOLOGY

Type I interferons and microbial metabolites of tryptophan modulate astrocyte activity and central nervous system inflammation via the aryl hydrocarbon receptor

(2016) Veit Rothhammer et al.   NATURE MEDICINE

Human Gut Bacteria Are Sensitive to Melatonin and Express Endogenous Circadian Rhythmicity

(2016) Jiffin K. Paulose et al.   PLoS One

Cell autonomous regulation of herpes and influenza virus infection by the circadian clock

(2016) Rachel S. Edgar et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Comparison of placenta samples with contamination controls does not provide evidence for a distinct placenta microbiota

(2016) Abigail P. Lauder et al.   Microbiome

Unconjugated Bile Acids Influence Expression of Circadian Genes: A Potential Mechanism for Microbe-Host Crosstalk

(2016) Kalaimathi Govindarajan et al.   PLoS One

Hepatic circadian clock oscillators and nuclear receptors integrate microbiome-derived signals

(2016) Alexandra Montagner et al.   Scientific Reports

Control of Brain Development, Function, and Behavior by the Microbiome

(2015) Timothy R. Sampson et al.   Cell Host & Microbe

Effects of Diurnal Variation of Gut Microbes and High-Fat Feeding on Host Circadian Clock Function and Metabolism

(2015) Vanessa Leone et al.   Cell Host & Microbe

Circadian clocks, epigenetics, and cancer

(2015) Selma Masri et al.   CURRENT OPINION IN ONCOLOGY

Host microbiota constantly control maturation and function of microglia in the CNS

(2015) Daniel Erny et al.   NATURE NEUROSCIENCE

Rhythmicity of the intestinal microbiota is regulated by gender and the host circadian clock

(2015) Xue Liang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Transplantability of a circadian clock to a noncircadian organism

(2015) A. H. Chen et al.   Science Advances

Transkingdom Control of Microbiota Diurnal Oscillations Promotes Metabolic Homeostasis

(2014) Christoph A. Thaiss et al.   CELL

Diet and Feeding Pattern Affect the Diurnal Dynamics of the Gut Microbiome

(2014) Amir Zarrinpar et al.   Cell Metabolism

Effect of diet on the intestinal microbiota and its activity

(2014) Erwin G. Zoetendal et al.   CURRENT OPINION IN GASTROENTEROLOGY

Circadian Clock Proteins and Immunity

(2014) Anne M. Curtis et al.   IMMUNITY

Gut Microbioma Population: An Indicator Really Sensible to Any Change in Age, Diet, Metabolic Syndrome, and Life-Style

(2014) Noce Annalisa et al.   MEDIATORS OF INFLAMMATION

'The clocks that time us'—circadian rhythms in neurodegenerative disorders

(2014) Aleksandar Videnovic et al.   Nature Reviews Neurology

Meta-analysis on night shift work and risk of metabolic syndrome

(2014) F. Wang et al.   Obesity Reviews

Circadian Disorganization Alters Intestinal Microbiota

(2014) Robin M. Voigt et al.   PLoS One

The Placenta Harbors a Unique Microbiome

(2014) K. Aagaard et al.   Science Translational Medicine

Diet, the human gut microbiota, and IBD

(2013) Gary D. Wu et al.   ANAEROBE

A meta-analysis on dose–response relationship between night shift work and the risk of breast cancer

(2013) F. Wang et al.   ANNALS OF ONCOLOGY

Homeostasis in Intestinal Epithelium Is Orchestrated by the Circadian Clock and Microbiota Cues Transduced by TLRs

(2013) Atish Mukherji et al.   CELL

Non-optimal codon usage is a mechanism to achieve circadian clock conditionality

(2013) Yao Xu et al.   NATURE

Diet rapidly and reproducibly alters the human gut microbiome

(2013) Lawrence A. David et al.   NATURE

Intestinal microbiota metabolism of l-carnitine, a nutrient in red meat, promotes atherosclerosis

(2013) Robert A Koeth et al.   NATURE MEDICINE

The gut microbiota and obesity: from correlation to causality

(2013) Liping Zhao   NATURE REVIEWS MICROBIOLOGY

Intestinal Microbial Metabolism of Phosphatidylcholine and Cardiovascular Risk

(2013) W.H. Wilson Tang et al.   NEW ENGLAND JOURNAL OF MEDICINE

Circadian clock regulates the host response to Salmonella

(2013) M. M. Bellet et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Robust Circadian Oscillations in Growing Cyanobacteria Require Transcriptional Feedback

(2013) S.-W. Teng et al.   SCIENCE

Knitting Up the Raveled Sleave of Care

(2013) G. Yang et al.   Science Translational Medicine

Cohabiting family members share microbiota with one another and with their dogs

(2013) Se Jin Song et al.   eLife

Central and Peripheral Circadian Clocks in Mammals

(2012) Jennifer A. Mohawk et al.   Annual Review of Neuroscience

Obesity in mice with adipocyte-specific deletion of clock component Arntl

(2012) Georgios K Paschos et al.   NATURE MEDICINE

The gut microbiota in IBD

(2012) Chaysavanh Manichanh et al.   Nature Reviews Gastroenterology & Hepatology

The interplay between the intestinal microbiota and the brain

(2012) Stephen M. Collins et al.   NATURE REVIEWS MICROBIOLOGY

Mind-altering microorganisms: the impact of the gut microbiota on brain and behaviour

(2012) John F. Cryan et al.   NATURE REVIEWS NEUROSCIENCE

Human Intestinal Lumen and Mucosa-Associated Microbiota in Patients with Colorectal Cancer

(2012) Weiguang Chen et al.   PLoS One

Gut microbiota and probiotics in colon tumorigenesis

(2011) Yuanmin Zhu et al.   CANCER LETTERS

Role of the Commensal Microbiota in Normal and Pathogenic Host Immune Responses

(2011) Dan R. Littman et al.   Cell Host & Microbe

Distal gut microbiota of adolescent children is different from that of adults

(2011) Richard Agans et al.   FEMS MICROBIOLOGY ECOLOGY

Gut flora metabolism of phosphatidylcholine promotes cardiovascular disease

(2011) Zeneng Wang et al.   NATURE

Enterotypes of the human gut microbiome

(2011) Manimozhiyan Arumugam et al.   NATURE

Evolution of time-keeping mechanisms: early emergence and adaptation to photoperiod

(2011) R. A. Hut et al.   PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

Circadian Rhythms, Aging, and Life Span in Mammals

(2011) Oren Froy   PHYSIOLOGY

Linking Long-Term Dietary Patterns with Gut Microbial Enterotypes

(2011) G. D. Wu et al.   SCIENCE

Enterobacteriaceae Act in Concert with the Gut Microbiota to Induce Spontaneous and Maternally Transmitted Colitis

(2010) Wendy S. Garrett et al.   Cell Host & Microbe

Metabolism and Circadian Rhythms—Implications for Obesity

(2010) Oren Froy   ENDOCRINE REVIEWS

Toward defining the autoimmune microbiome for type 1 diabetes

(2010) Adriana Giongo et al.   ISME Journal

Long-term impacts of antibiotic exposure on the human intestinal microbiota

(2010) C. Jernberg et al.   MICROBIOLOGY-SGM

Disruption of the clock components CLOCK and BMAL1 leads to hypoinsulinaemia and diabetes

(2010) Biliana Marcheva et al.   NATURE

A human gut microbial gene catalogue established by metagenomic sequencing

(2010) Junjie Qin et al.   NATURE

Gut Microbiota in Health and Disease

(2010) Inna Sekirov et al.   PHYSIOLOGICAL REVIEWS

Through Ageing, and Beyond: Gut Microbiota and Inflammatory Status in Seniors and Centenarians

(2010) Elena Biagi et al.   PLoS One

Composition, variability, and temporal stability of the intestinal microbiota of the elderly

(2010) M. J. Claesson et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Individuality in gut microbiota composition is a complex polygenic trait shaped by multiple environmental and host genetic factors

(2010) A. K. Benson et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Succession of microbial consortia in the developing infant gut microbiome

(2010) J. E. Koenig et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Delivery mode shapes the acquisition and structure of the initial microbiota across multiple body habitats in newborns

(2010) M. G. Dominguez-Bello et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Circadian Integration of Metabolism and Energetics

(2010) J. Bass et al.   SCIENCE

Establishment of the gut microbiota in Western infants

(2009) I Adlerberth et al.   ACTA PAEDIATRICA

Rhythmic changes in colonic motility are regulated by period genes

(2009) Willemijntje A. Hoogerwerf et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Towards the human intestinal microbiota phylogenetic core

(2009) Julien Tap et al.   ENVIRONMENTAL MICROBIOLOGY

Clock is important for food and circadian regulation of macronutrient absorption in mice

(2009) Xiaoyue Pan et al.   JOURNAL OF LIPID RESEARCH

The Human Microbiome Project: Getting to the Guts of the Matter in Cancer Epidemiology

(2008) J. W. Lampe   CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION

The Meter of Metabolism

(2008) Carla B. Green et al.   CELL

Diet-Induced Obesity Is Linked to Marked but Reversible Alterations in the Mouse Distal Gut Microbiome

(2008) Peter J. Turnbaugh et al.   Cell Host & Microbe

Molecular analysis of the gut microbiota of identical twins with Crohn's disease

(2008) Johan Dicksved et al.   ISME Journal

Innate immunity and intestinal microbiota in the development of Type 1 diabetes

(2008) Li Wen et al.   NATURE