Dual regulation of Stat1 and Stat3 by the tumor suppressor protein PML contributes to interferon α-mediated inhibition of angiogenesis

PML suppresses IL-6-induced STAT3 activation by interfering with STAT3 and HDAC3 interaction

(2015) Masaya Kato et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Translational control of PML contributes to TNFα-induced apoptosis of MCF7 breast cancer cells and decreased angiogenesis in HUVECs

(2015) K-S Hsu et al.   CELL DEATH AND DIFFERENTIATION

Distal regulatory element of the STAT1 gene potentially mediates positive feedback control of STAT1 expression

(2015) Katsutoshi Yuasa et al.   GENES TO CELLS

Transcriptome Sequencing to Identify Transcription Factor Regulatory Network and Alternative Splicing in Endothelial Cells Under VEGF Stimulation

(2015) Fang Liu et al.   JOURNAL OF MOLECULAR NEUROSCIENCE

STAT1 deficiency redirects IFN signalling toward suppression of TLR response through a feedback activation of STAT3

(2015) Hun Sik Kim et al.   Scientific Reports

Identification and characterization of a novel ISG15-ubiquitin mixed chain and its role in regulating protein homeostasis

(2015) Jun-Bao Fan et al.   Scientific Reports

Colorectal cancer cell-derived microvesicles containing microRNA-1246 promote angiogenesis by activating Smad 1/5/8 signaling elicited by PML down-regulation in endothelial cells

(2014) Nami Yamada et al.   Biochimica et Biophysica Acta-Gene Regulatory Mechanisms

Isg15 controls p53 stability and functions

(2014) Yi-Fu Huang et al.   CELL CYCLE

PML nuclear bodies: regulation, function and therapeutic perspectives

(2014) Umut Sahin et al.   JOURNAL OF PATHOLOGY

A Cellular System that Degrades Misfolded Proteins and Protects against Neurodegeneration

(2014) Lili Guo et al.   MOLECULAR CELL

Transmembrane protein ESDN promotes endothelial VEGF signaling and regulates angiogenesis

(2013) Lei Nie et al.   JOURNAL OF CLINICAL INVESTIGATION

New Strategies to Direct Therapeutic Targeting of PML to Treat Cancers

(2013) Kamil Wolyniec et al.   Frontiers in Oncology

Microarray analysis revealing common and distinct functions of promyelocytic leukemia protein (PML) and tumor necrosis factor alpha (TNFα) signaling in endothelial cells

(2012) Xiwen Cheng et al.   BMC GENOMICS

IFNs, ISGylation and cancer: Cui prodest?

(2012) Andrea Sgorbissa et al.   CYTOKINE & GROWTH FACTOR REVIEWS

The JAK-STAT Pathway at Twenty

(2012) George R. Stark et al.   IMMUNITY

Promyelocytic Leukemia Protein (PML) Regulates Endothelial Cell Network Formation and Migration in Response to Tumor Necrosis Factor α (TNFα) and Interferon α (IFNα)

(2012) Xiwen Cheng et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

USP18 is a key regulator of the interferon-driven gene network modulating pancreatic beta cell inflammation and apoptosis

(2012) I Santin et al.   Cell Death & Disease

Opposed regulation of type I IFN-induced STAT3 and ISGF3 transcriptional activities by histone deacetylases (HDACS) 1 and 2

(2011) Laura Icardi et al.   FASEB JOURNAL

STAT3 Negatively Regulates Type I IFN-Mediated Antiviral Response

(2011) W.-B. Wang et al.   JOURNAL OF IMMUNOLOGY

Gene network inference and visualization tools for biologists: application to new human transcriptome datasets

(2011) Daniel Hurley et al.   NUCLEIC ACIDS RESEARCH

Integrin affinity modulation in angiogenesis

(2010) Ganapati H. Mahabeleshwar et al.   CELL CYCLE

N-Ethyl-N-Nitrosourea-Induced Mutation in Ubiquitin-Specific Peptidase 18 Causes Hyperactivation of IFN-   Signaling and Suppresses STAT4-Induced IFN-  Production, Resulting in Increased Susceptibility to Salmonella Typhimurium

(2010) E. Richer et al.   JOURNAL OF IMMUNOLOGY

The Functions of Signal Transducers and Activators of Transcriptions 1 and 3 as Cytokine-Inducible Proteins

(2010) HyeonJoo Cheon et al.   JOURNAL OF INTERFERON AND CYTOKINE RESEARCH

Interferon-Stimulated Gene 15 and the Protein ISGylation System

(2010) Dongxian Zhang et al.   JOURNAL OF INTERFERON AND CYTOKINE RESEARCH

The ISG15 Conjugation System Broadly Targets Newly Synthesized Proteins: Implications for the Antiviral Function of ISG15

(2010) Larissa A. Durfee et al.   MOLECULAR CELL

Inhibition of Tumor Cell Motility by the Interferon-inducible GTPase MxA

(2009) J. Frederic Mushinski et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Cytokine expression and signaling in drug-induced cellular senescence

(2009) Z Novakova et al.   ONCOGENE

Unphosphorylated STAT1 prolongs the expression of interferon-induced immune regulatory genes

(2009) H. Cheon et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The IL-6 family of cytokines modulates STAT3 activation by desumoylation of PML through SENP1 induction

(2008) Norihiko Ohbayashi et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Understanding the immunoangiostatic CXC chemokine network

(2008) M. L. Balestrieri et al.   CARDIOVASCULAR RESEARCH

Regulation of apoptosis by PML and the PML-NBs

(2008) R Bernardi et al.   ONCOGENE

Ups and downs: The STAT1:STAT3 seesaw of Interferon and gp130 receptor signalling

(2008) Gabriella Regis et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY