The resolution of acute inflammation induced by cyclic AMP is dependent on annexin A1

Inhibition of Phosphodiesterase-4 during Pneumococcal Pneumonia Reduces Inflammation and Lung Injury in Mice

(2016) Luciana P. Tavares et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Prostaglandin E2 promotes M2 polarization of macrophages via a cAMP/CREB signaling pathway and deactivates granulocytes in teleost fish

(2016) Jana Montero et al.   FISH & SHELLFISH IMMUNOLOGY

Proresolving Actions of Synthetic and Natural Protease Inhibitors Are Mediated by Annexin A1

(2016) Juliana P. Vago et al.   JOURNAL OF IMMUNOLOGY

The role of neutrophils in inflammation resolution

(2016) Hefin R. Jones et al.   SEMINARS IN IMMUNOLOGY

Reduced lipolysis response to adipose afferent reflex involved in impaired activation of adrenoceptor-cAMP-PKA-hormone sensitive lipase pathway in obesity

(2016) Lei Ding et al.   Scientific Reports

Prostaglandin E2inhibits neutrophil extracellular trap formation through production of cyclic AMP

(2015) Kyosuke Shishikura et al.   BRITISH JOURNAL OF PHARMACOLOGY

Mcl-1 is vital for neutrophil survival

(2015) Mark P. Murphy et al.   IMMUNOLOGIC RESEARCH

The Role and Effects of Glucocorticoid-Induced Leucine Zipper in the Context of Inflammation Resolution

(2015) Juliana P. Vago et al.   JOURNAL OF IMMUNOLOGY

Prostaglandin E2Inhibits NLRP3 Inflammasome Activation through EP4 Receptor and Intracellular Cyclic AMP in Human Macrophages

(2015) Milena Sokolowska et al.   JOURNAL OF IMMUNOLOGY

Advances in targeting cyclic nucleotide phosphodiesterases

(2014) Donald H. Maurice et al.   NATURE REVIEWS DRUG DISCOVERY

Cyclic Nucleotide Phosphodiesterases: important signaling modulators and therapeutic targets

(2014) F Ahmad et al.   ORAL DISEASES

cAMP signaling in subcellular compartments

(2014) Konstantinos Lefkimmiatis et al.   PHARMACOLOGY & THERAPEUTICS

Resolvin D1-mediated NOX2 inactivation rescues macrophages undertaking efferocytosis from oxidative stress-induced apoptosis

(2013) Ha-Na Lee et al.   BIOCHEMICAL PHARMACOLOGY

Pharmacological strategies to resolve acute inflammation

(2013) Lirlândia Pires Sousa et al.   CURRENT OPINION IN PHARMACOLOGY

Shaping the Murine Macrophage Phenotype: IL-4 and Cyclic AMP Synergistically Activate the Arginase I Promoter

(2013) K. E. Sheldon et al.   JOURNAL OF IMMUNOLOGY

Proresolving and Tissue-Protective Actions of Annexin A1-Based Cleavage-Resistant Peptides Are Mediated by Formyl Peptide Receptor 2/Lipoxin A4 Receptor

(2013) J. Dalli et al.   JOURNAL OF IMMUNOLOGY

Inhaled Carbon Monoxide Accelerates Resolution of Inflammation via Unique Proresolving Mediator-Heme Oxygenase-1 Circuits

(2013) N. Chiang et al.   JOURNAL OF IMMUNOLOGY

Resolution of inflammation: Mechanisms and opportunity for drug development

(2013) Ana L. Alessandri et al.   PHARMACOLOGY & THERAPEUTICS

Anti-Allergic Cromones Inhibit Histamine and Eicosanoid Release from Activated Human and Murine Mast Cells by Releasing Annexin A1

(2013) Samia Yazid et al.   PLoS One

A Novel Anti-Inflammatory and Pro-Resolving Role for Resolvin D1 in Acute Cigarette Smoke-Induced Lung Inflammation

(2013) Hsi-Min Hsiao et al.   PLoS One

Ligand-specific conformational change of the G-protein-coupled receptor ALX/FPR2 determines proresolving functional responses

(2013) S. N. Cooray et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Gene expression signature-based approach identifies a pro-resolving mechanism of action for histone deacetylase inhibitors

(2012) T Montero-Melendez et al.   CELL DEATH AND DIFFERENTIATION

Norepinephrine differentially modulates the innate inflammatory response provoked by amyloid-β peptide via action at β-adrenoceptors and activation of cAMP/PKA pathway in human THP-1 macrophages

(2012) Ji Hye Yang et al.   EXPERIMENTAL NEUROLOGY

Flavones induce neutrophil apoptosis by down-regulation of Mcl-1 via a proteasomal-dependent pathway

(2012) Christopher D. Lucas et al.   FASEB JOURNAL

Annexin A1 Interaction with the FPR2/ALX Receptor

(2012) Stefania Bena et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Annexin A1 modulates natural and glucocorticoid-induced resolution of inflammation by enhancing neutrophil apoptosis

(2012) Juliana P. Vago et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Annexin A1 Induces Skeletal Muscle Cell Migration Acting through Formyl Peptide Receptors

(2012) Valentina Bizzarro et al.   PLoS One

Emerging roles for lysophosphatidylserine in resolution of inflammation

(2012) S. Courtney Frasch et al.   PROGRESS IN LIPID RESEARCH

Annexin A1 and the regulation of innate and adaptive immunity

(2012) Felicity N. E. Gavins et al.   Frontiers in Immunology

The Melanocortin Agonist AP214 Exerts Anti-Inflammatory and Proresolving Properties

(2011) Trinidad Montero-Melendez et al.   AMERICAN JOURNAL OF PATHOLOGY

Activation of the Annexin A1 Pathway Underlies the Protective Effects Exerted by Estrogen in Polymorphonuclear Leukocytes

(2011) Suchita Nadkarni et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Annexin A1 regulates neutrophil clearance by macrophages in the mouse bone marrow

(2011) Jesmond Dalli et al.   FASEB JOURNAL

Resolvin D1 and Its Precursor Docosahexaenoic Acid Promote Resolution of Adipose Tissue Inflammation by Eliciting Macrophage Polarization toward an M2-Like Phenotype

(2011) Esther Titos et al.   JOURNAL OF IMMUNOLOGY

Evidence for an Anti-Inflammatory Loop Centered on Polymorphonuclear Leukocyte Formyl Peptide Receptor 2/Lipoxin A4 Receptor and Operative in the Inflamed Microvasculature

(2011) V. Brancaleone et al.   JOURNAL OF IMMUNOLOGY

Propofol Inhibits the Activation of p38 through Up-Regulating the Expression of Annexin A1 to Exert Its Anti-Inflammation Effect

(2011) Jing Tang et al.   PLoS One

Regulation of Neutrophil Survival/Apoptosis by Mcl-1

(2011) Eric Milot et al.   TheScientificWorldJOURNAL

Antiallergic Cromones Inhibit Neutrophil Recruitment Onto Vascular Endothelium via Annexin-A1 Mobilization

(2010) Samia Yazid et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Design and characterization of a cleavage-resistant Annexin A1 mutant to control inflammation in the microvasculature

(2010) M. Pederzoli-Ribeil et al.   BLOOD

PDE4 inhibition drives resolution of neutrophilic inflammation by inducing apoptosis in a PKA-PI3K/Akt-dependent and NF-κB-independent manner

(2010) Lirlândia P. Sousa et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Cyclic AMP enhances resolution of allergic pleurisy by promoting inflammatory cell apoptosis via inhibition of PI3K/Akt and NF-κB

(2009) Lirlândia P. Sousa et al.   BIOCHEMICAL PHARMACOLOGY

Cromoglycate drugs suppress eicosanoid generation in U937 cells by promoting the release of Anx-A1

(2009) Samia Yazid et al.   BIOCHEMICAL PHARMACOLOGY

Nonresolving Inflammation in gp91phox-/- Mice, a Model of Human Chronic Granulomatous Disease, Has Lower Adenosine and Cyclic Adenosine 5'-Monophosphate

(2009) R. Rajakariar et al.   JOURNAL OF IMMUNOLOGY

Prostaglandin E2 Inhibits Advanced Glycation End Product-Induced Adhesion Molecule Expression, Cytokine Production, and Lymphocyte Proliferation in Human Peripheral Blood Mononuclear Cells

(2009) H. K. Takahashi et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

Resolution-phase macrophages possess a unique inflammatory phenotype that is controlled by cAMP

(2008) J. Bystrom et al.   BLOOD

Phosphodiesterase 4 inhibitors delay human eosinophil and neutrophil apoptosis in the absence and presence of salbutamol

(2007) Jouni Parkkonen et al.   PULMONARY PHARMACOLOGY & THERAPEUTICS