Pharmacochaperoning in aDrosophilamodel system rescues human dopamine transporter variants associated with infantile/juvenile parkinsonism
出版年份 2017 全文链接
标题
Pharmacochaperoning in aDrosophilamodel system rescues human dopamine transporter variants associated with infantile/juvenile parkinsonism
作者
关键词
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出版物
JOURNAL OF BIOLOGICAL CHEMISTRY
Volume 292, Issue 47, Pages 19250-19265
出版商
American Society for Biochemistry & Molecular Biology (ASBMB)
发表日期
2017-10-03
DOI
10.1074/jbc.m117.797092
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注意:仅列出部分参考文献,下载原文获取全部文献信息。- Occupancy of the Zinc-binding Site by Transition Metals Decreases the Substrate Affinity of the Human Dopamine Transporter by an Allosteric Mechanism
- (2017) Yang Li et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Conformational state interactions provide clues to the pharmacochaperone potential of serotonin transporter partial substrates
- (2017) Shreyas Bhat et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Sequence determinants of the Caenhorhabditis elegans dopamine transporter dictating in vivo axonal export and synaptic localization
- (2017) Sarah B. Robinson et al. MOLECULAR AND CELLULAR NEUROSCIENCE
- CRISPR-Cas-Induced Mutants Identify a Requirement for dSTIM in Larval Dopaminergic Cells of Drosophila melanogaster
- (2017) Trayambak Pathak et al. G3-Genes Genomes Genetics
- ACaenorhabditis elegansmodel to study dopamine transporter deficiency syndrome
- (2016) Placido Illiano et al. EUROPEAN JOURNAL OF NEUROSCIENCE
- The D1 family dopamine receptor,DopR, potentiates hind leg grooming behavior inDrosophila
- (2016) E. Pitmon et al. GENES BRAIN AND BEHAVIOR
- Pharmacological Chaperones of the Dopamine Transporter Rescue Dopamine Transporter Deficiency Syndrome Mutations in Heterologous Cells
- (2016) Pieter Beerepoot et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Functional Rescue of a MisfoldedDrosophila melanogasterDopamine Transporter Mutant Associated with a Sleepless Phenotype by Pharmacological Chaperones
- (2016) Ameya Kasture et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Operation of a homeostatic sleep switch
- (2016) Diogo Pimentel et al. NATURE
- Treatment of Fabry’s Disease with the Pharmacologic Chaperone Migalastat
- (2016) Dominique P. Germain et al. NEW ENGLAND JOURNAL OF MEDICINE
- Neurofibromin Loss of Function Drives Excessive Grooming in Drosophila
- (2016) Lanikea B. King et al. G3-Genes Genomes Genetics
- Dual Action of Zn2+on the Transport Cycle of the Dopamine Transporter
- (2015) Yang Li et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- A Salt Bridge Linking the First Intracellular Loop with the C Terminus Facilitates the Folding of the Serotonin Transporter
- (2015) Florian Koban et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Amphetamines, new psychoactive drugs and the monoamine transporter cycle
- (2015) Harald H. Sitte et al. TRENDS IN PHARMACOLOGICAL SCIENCES
- Tracking Single Serotonin Transporter Molecules at the Endoplasmic Reticulum and Plasma Membrane
- (2014) Andreas Anderluh et al. BIOPHYSICAL JOURNAL
- Dopamine transporter deficiency syndrome: phenotypic spectrum from infancy to adulthood
- (2014) Joanne Ng et al. BRAIN
- Molecular Basis of the Dominant Negative Effect of a Glycine Transporter 2 Mutation Associated with Hyperekplexia
- (2014) Esther Arribas-González et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- A Cytosolic Relay of Heat Shock Proteins HSP70-1A and HSP90β Monitors the Folding Trajectory of the Serotonin Transporter
- (2014) Ali El-Kasaby et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Ascending-dose study of noribogaine in healthy volunteers: Pharmacokinetics, pharmacodynamics, safety, and tolerability
- (2014) Paul Glue et al. JOURNAL OF CLINICAL PHARMACOLOGY
- Effects of the Chemical Chaperone 4-Phenylbutylate on the Function of the Serotonin Transporter (SERT) Expressed in COS-7 Cells
- (2013) Masayuki Fujiwara et al. JOURNAL OF PHARMACOLOGICAL SCIENCES
- The SLC6 transporters: perspectives on structure, functions, regulation, and models for transporter dysfunction
- (2013) Gary Rudnick et al. PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY
- Defining the blanks – Pharmacochaperoning of SLC6 transporters and ABC transporters
- (2013) Peter Chiba et al. PHARMACOLOGICAL RESEARCH
- The solute carrier 6 family of transporters
- (2012) Stefan Bröer et al. BRITISH JOURNAL OF PHARMACOLOGY
- Mutations in the GlyT2 Gene (SLC6A5) Are a Second Major Cause of Startle Disease
- (2012) Eloisa Carta et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- The Mechanistic Basis for Noncompetitive Ibogaine Inhibition of Serotonin and Dopamine Transporters
- (2012) Simon Bulling et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Correction of the F508del-CFTR protein processing defect in vitro by the investigational drug VX-809
- (2011) F. Van Goor et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Dopamine in Drosophila: setting arousal thresholds in a miniature brain
- (2011) B. Van Swinderen et al. PROCEEDINGS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES
- Mutations in the Carboxyl-terminal SEC24 Binding Motif of the Serotonin Transporter Impair Folding of the Transporter
- (2010) Ali El-Kasaby et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Clinical and molecular characterisation of hereditary dopamine transporter deficiency syndrome: an observational cohort and experimental study
- (2010) Manju A Kurian et al. LANCET NEUROLOGY
- Behavioral consequences of dopamine deficiency in the Drosophila central nervous system
- (2010) T. Riemensperger et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- pySolo: a complete suite for sleep analysis in Drosophila
- (2009) G. F. Gilestro et al. BIOINFORMATICS
- Homozygous loss-of-function mutations in the gene encoding the dopamine transporter are associated with infantile parkinsonism-dystonia
- (2009) Manju A. Kurian et al. JOURNAL OF CLINICAL INVESTIGATION
- A Small Molecule Inhibitor of Inducible Heat Shock Protein 70
- (2009) J. I-Ju Leu et al. MOLECULAR CELL
- Rescue of CF airway epithelial cell function in vitro by a CFTR potentiator, VX-770
- (2009) F. Van Goor et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
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