In silicomodeling of the cryptic E2∼ubiquitin–binding site of E6-associated protein (E6AP)/UBE3A reveals the mechanism of polyubiquitin chain assembly
出版年份 2017 全文链接
标题
In silicomodeling of the cryptic E2∼ubiquitin–binding site of E6-associated protein (E6AP)/UBE3A reveals the mechanism of polyubiquitin chain assembly
作者
关键词
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出版物
JOURNAL OF BIOLOGICAL CHEMISTRY
Volume 292, Issue 44, Pages 18006-18023
出版商
American Society for Biochemistry & Molecular Biology (ASBMB)
发表日期
2017-09-19
DOI
10.1074/jbc.m117.813477
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注意:仅列出部分参考文献,下载原文获取全部文献信息。- Molecular insights into RBR E3 ligase ubiquitin transfer mechanisms
- (2016) Katja K Dove et al. EMBO REPORTS
- An Autism-Linked Mutation Disables Phosphorylation Control of UBE3A
- (2015) Jason J. Yi et al. CELL
- Convergent Evolution in the Assembly of Polyubiquitin Degradation Signals by theShigella flexneriIpaH9.8 Ligase
- (2014) Daniel J. Edwards et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- The E3 ubiquitin ligase UBE3A is an integral component of the molecular circadian clock through regulating the BMAL1 transcription factor
- (2014) Nicole C. Gossan et al. NUCLEIC ACIDS RESEARCH
- Structural and Functional Framework for the Autoinhibition of Nedd4-Family Ubiquitin Ligases
- (2014) Sara Mari et al. STRUCTURE
- Mammalian HECT ubiquitin-protein ligases: Biological and pathophysiological aspects
- (2013) Martin Scheffner et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH
- A Genomic Survey of HECT Ubiquitin Ligases in Eukaryotes Reveals Independent Expansions of the HECT System in Several Lineages
- (2013) Xavier Grau-Bové et al. Genome Biology and Evolution
- Tripartite Motif Ligases Catalyze Polyubiquitin Chain Formation through a Cooperative Allosteric Mechanism
- (2013) Frederick C. Streich et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- The Active Form of E6-associated protein (E6AP)/UBE3A Ubiquitin Ligase Is an Oligomer
- (2013) Virginia P. Ronchi et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- E6AP/UBE3A Ubiquitin Ligase Harbors Two E2∼ubiquitin Binding Sites
- (2013) Virginia P. Ronchi et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Structure of a ubiquitin-loaded HECT ligase reveals the molecular basis for catalytic priming
- (2013) Elena Maspero et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- E3 Ubiquitin Ligase E6AP Negatively Regulates Adipogenesis by Downregulating Proadipogenic Factor C/EBPalpha
- (2013) Pooja Pal et al. PLoS One
- Mechanism of ubiquitin ligation and lysine prioritization by a HECT E3
- (2013) Hari B Kamadurai et al. eLife
- Structural Insights into the Conformation and Oligomerization of E2∼Ubiquitin Conjugates
- (2012) Richard C. Page et al. BIOCHEMISTRY
- Prader-Willi syndrome
- (2012) Suzanne B. Cassidy et al. GENETICS IN MEDICINE
- Structure of an E3:E2∼Ub Complex Reveals an Allosteric Mechanism Shared among RING/U-box Ligases
- (2012) Jonathan N. Pruneda et al. MOLECULAR CELL
- Interpreting cancer genomes using systematic host network perturbations by tumour virus proteins
- (2012) Orit Rozenblatt-Rosen et al. NATURE
- Structure of a RING E3 ligase and ubiquitin-loaded E2 primed for catalysis
- (2012) Anna Plechanovová et al. NATURE
- Ubiquitin in Motion: Structural Studies of the Ubiquitin-Conjugating Enzyme∼Ubiquitin Conjugate
- (2011) Jonathan N. Pruneda et al. BIOCHEMISTRY
- Structure of the HECT:ubiquitin complex and its role in ubiquitin chain elongation
- (2011) Elena Maspero et al. EMBO REPORTS
- E1-E2 Interactions in Ubiquitin and Nedd8 Ligation Pathways
- (2011) Zeynep Tokgöz et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- The Relative Rates of Thiol–Thioester Exchange and Hydrolysis for Alkyl and Aryl Thioalkanoates in Water
- (2011) Paul J. Bracher et al. ORIGINS OF LIFE AND EVOLUTION OF BIOSPHERES
- Animal HECT ubiquitin ligases: evolution and functional implications
- (2010) Ignacio Marín BMC EVOLUTIONARY BIOLOGY
- Role of the ubiquitin system in regulating ion transport
- (2010) Daniela Rotin et al. PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY
- Protein−Protein Recognition between Acyltransferases and Acyl Carrier Proteins in Multimodular Polyketide Synthases
- (2009) Fong T. Wong et al. BIOCHEMISTRY
- HPV16 E6-Induced and E6AP-Dependent Inhibition of the Transcriptional Coactivator hADA3 in Human Cervical Carcinoma Cells
- (2009) Ying Hu et al. CANCER INVESTIGATION
- Ubiquitination, Ubiquitin-like Modifiers, and Deubiquitination in Viral Infection
- (2009) Marisa K. Isaacson et al. Cell Host & Microbe
- The Ubiquitin Ligase E6-AP Is Induced and Recruited to Aggresomes in Response to Proteasome Inhibition and May Be Involved in the Ubiquitination of Hsp70-bound Misfolded Proteins
- (2009) Amit Mishra et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Polyubiquitination by HECT E3s and the Determinants of Chain Type Specificity
- (2009) H. C. Kim et al. MOLECULAR AND CELLULAR BIOLOGY
- Insights into Ubiquitin Transfer Cascades from a Structure of a UbcH5B∼Ubiquitin-HECTNEDD4L Complex
- (2009) Hari B. Kamadurai et al. MOLECULAR CELL
- Physiological functions of the HECT family of ubiquitin ligases
- (2009) Daniela Rotin et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- UBE3A/E6-AP regulates cell proliferation by promoting proteasomal degradation of p27
- (2009) Amit Mishra et al. NEUROBIOLOGY OF DISEASE
- A model for the interaction between NF-kappa-B and ASPP2 suggests an I-kappa-B-like binding mechanism
- (2009) Hadar Benyamini et al. PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS
- Cellular binding partners of the human papillomavirus E6 protein
- (2008) Sandy S. Tungteakkhun et al. ARCHIVES OF VIROLOGY
- The HECT Family of E3 Ubiquitin Ligases: Multiple Players in Cancer Development
- (2008) Francesca Bernassola et al. CANCER CELL
- ISG15 Inhibits Nedd4 Ubiquitin E3 Activity and Enhances the Innate Antiviral Response
- (2008) Oxana A. Malakhova et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- E6-AP Promotes Misfolded Polyglutamine Proteins for Proteasomal Degradation and Suppresses Polyglutamine Protein Aggregation and Toxicity
- (2008) Amit Mishra et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- The E6 Oncoproteins from Human Betapapillomaviruses Differentially Activate Telomerase through an E6AP-Dependent Mechanism and Prolong the Lifespan of Primary Keratinocytes
- (2008) K. M. Bedard et al. JOURNAL OF VIROLOGY
- Endosomal sorting and signalling: an emerging role for sorting nexins
- (2008) Peter J. Cullen NATURE REVIEWS MOLECULAR CELL BIOLOGY
- ISG15 inhibits Ebola VP40 VLP budding in an L-domain-dependent manner by blocking Nedd4 ligase activity
- (2008) A. Okumura et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
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