E6AP/UBE3A Ubiquitin Ligase Harbors Two E2∼ubiquitin Binding Sites

Structure of the HECT:ubiquitin complex and its role in ubiquitin chain elongation

(2011) Elena Maspero et al.   EMBO REPORTS

Structure and function of a HECT domain ubiquitin-binding site

(2011) Hyung Cheol Kim et al.   EMBO REPORTS

E1-E2 Interactions in Ubiquitin and Nedd8 Ligation Pathways

(2011) Zeynep Tokgöz et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

WWP2 is an E3 ubiquitin ligase for PTEN

(2011) Subbareddy Maddika et al.   NATURE CELL BIOLOGY

EphB-Mediated Degradation of the RhoA GEF Ephexin5 Relieves a Developmental Brake on Excitatory Synapse Formation

(2010) Seth S. Margolis et al.   CELL

The Angelman Syndrome Protein Ube3A Regulates Synapse Development by Ubiquitinating Arc

(2010) Paul L. Greer et al.   CELL

Kinetics of the Transfer of Ubiquitin from UbcH7 to E6AP

(2009) Carrie Purbeck et al.   BIOCHEMISTRY

HPV16 E6-Induced and E6AP-Dependent Inhibition of the Transcriptional Coactivator hADA3 in Human Cervical Carcinoma Cells

(2009) Ying Hu et al.   CANCER INVESTIGATION

Ubiquitination, Ubiquitin-like Modifiers, and Deubiquitination in Viral Infection

(2009) Marisa K. Isaacson et al.   Cell Host & Microbe

A Structural Element within the HUWE1 HECT Domain Modulates Self-ubiquitination and Substrate Ubiquitination Activities

(2009) Renuka K. Pandya et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Ubiquitin Ligase E6-AP Is Induced and Recruited to Aggresomes in Response to Proteasome Inhibition and May Be Involved in the Ubiquitination of Hsp70-bound Misfolded Proteins

(2009) Amit Mishra et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Polyubiquitination by HECT E3s and the Determinants of Chain Type Specificity

(2009) H. C. Kim et al.   MOLECULAR AND CELLULAR BIOLOGY

Insights into Ubiquitin Transfer Cascades from a Structure of a UbcH5B∼Ubiquitin-HECTNEDD4L Complex

(2009) Hari B. Kamadurai et al.   MOLECULAR CELL

Physiological functions of the HECT family of ubiquitin ligases

(2009) Daniela Rotin et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

The Basis for Selective E1-E2 Interactions in the ISG15 Conjugation System

(2008) Larissa A. Durfee et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

E6-AP Promotes Misfolded Polyglutamine Proteins for Proteasomal Degradation and Suppresses Polyglutamine Protein Aggregation and Toxicity

(2008) Amit Mishra et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Recognition of Polyubiquitin Isoforms by the Multiple Ubiquitin Binding Modules of Isopeptidase T

(2008) Francisca E. Reyes-Turcu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The E6 Oncoproteins from Human Betapapillomaviruses Differentially Activate Telomerase through an E6AP-Dependent Mechanism and Prolong the Lifespan of Primary Keratinocytes

(2008) K. M. Bedard et al.   JOURNAL OF VIROLOGY