Deconvoluting AMP-activated protein kinase (AMPK) adenine nucleotide binding and sensing

Physiological Expression ofAMPKγ2RGMutation Causes Wolff-Parkinson-White Syndrome and Induces Kidney Injury in Mice

(2016) Xiaodong Yang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Nuclear receptors and AMPK: can exercise mimetics cure diabetes?

(2016) Christopher E Wall et al.   JOURNAL OF MOLECULAR ENDOCRINOLOGY

Unraveling the actions of AMP-activated protein kinase in metabolic diseases: Systemic to molecular insights

(2016) Karen A. Weikel et al.   METABOLISM-CLINICAL AND EXPERIMENTAL

Structural basis of allosteric and synergistic activation of AMPK by furan-2-phosphonic derivative C2 binding

(2016) Christopher G. Langendorf et al.   Nature Communications

Integrative Analysis of PRKAG2 Cardiomyopathy iPS and Microtissue Models Identifies AMPK as a Regulator of Metabolism, Survival, and Fibrosis

(2016) J. Travis Hinson et al.   Cell Reports

Probing the enzyme kinetics, allosteric modulation and activation of  1- and  2-subunit-containing AMP-activated protein kinase (AMPK) heterotrimeric complexes by pharmacological and physiological activators

(2015) F. Rajamohan et al.   BIOCHEMICAL JOURNAL

Differential regulation by AMP and ADP of AMPK complexes containing different   subunit isoforms

(2015) F. A. Ross et al.   BIOCHEMICAL JOURNAL

The AMP-activated protein kinase (AMPK) and cancer: Many faces of a metabolic regulator

(2015) Brandon Faubert et al.   CANCER LETTERS

Neuronal CRTC-1 Governs Systemic Mitochondrial Metabolism and Lifespan via a Catecholamine Signal

(2015) Kristopher Burkewitz et al.   CELL

Structural basis of AMPK regulation by adenine nucleotides and glycogen

(2014) Xiaodan Li et al.   CELL RESEARCH

Mutation in the γ2-Subunit of AMP-Activated Protein Kinase Stimulates Cardiomyocyte Proliferation and Hypertrophy Independent of Glycogen Storage

(2014) Maengjo Kim et al.   CIRCULATION RESEARCH

Structural Basis for AMPK Activation: Natural and Synthetic Ligands Regulate Kinase Activity from Opposite Poles by Different Molecular Mechanisms

(2014) Matthew F. Calabrese et al.   STRUCTURE

AMP Is a True Physiological Regulator of AMP-Activated Protein Kinase by Both Allosteric Activation and Enhancing Net Phosphorylation

(2013) Graeme J. Gowans et al.   Cell Metabolism

AMP as a Low-Energy Charge Signal Autonomously Initiates Assembly of AXIN-AMPK-LKB1 Complex for AMPK Activation

(2013) Ya-Lin Zhang et al.   Cell Metabolism

Time Window Expansion for HDX Analysis of an Intrinsically Disordered Protein

(2013) Devrishi Goswami et al.   JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY

Conserved regulatory elements in AMPK

(2013) Lei Chen et al.   NATURE

Structural basis of AMPK regulation by small molecule activators

(2013) Bing Xiao et al.   Nature Communications

AMP-Activated Protein Kinase: A Target for Drugs both Ancient and Modern

(2012) D. Grahame Hardie et al.   CHEMISTRY & BIOLOGY

HDX Workbench: Software for the Analysis of H/D Exchange MS Data

(2012) Bruce D. Pascal et al.   JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY

AMP-activated protein kinase undergoes nucleotide-dependent conformational changes

(2012) Lei Chen et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

A Fluorescent Reporter of AMPK Activity and Cellular Energy Stress

(2011) Peiling Tsou et al.   Cell Metabolism

AMP-activated protein kinase--an energy sensor that regulates all aspects of cell function

(2011) D. G. Hardie   GENES & DEVELOPMENT

Lifespan extension induced by AMPK and calcineurin is mediated by CRTC-1 and CREB

(2011) William Mair et al.   NATURE

Structure of mammalian AMPK and its regulation by ADP

(2011) Bing Xiao et al.   NATURE

The AMPK signalling pathway coordinates cell growth, autophagy and metabolism

(2011) Maria M. Mihaylova et al.   NATURE CELL BIOLOGY

AMPK Is a Direct Adenylate Charge-Regulated Protein Kinase

(2011) J. S. Oakhill et al.   SCIENCE

Naturally occurring R225W mutation of the gene encoding AMP-activated protein kinase (AMPK)γ3 results in increased oxidative capacity and glucose uptake in human primary myotubes

(2010) S. A. Crawford et al.   DIABETOLOGIA

 -Subunit myristoylation is the gatekeeper for initiating metabolic stress sensing by AMP-activated protein kinase (AMPK)

(2010) J. S. Oakhill et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Effects of exercise on muscle glycogen synthesis signalling and enzyme activities in pigs carrying thePRKAG3mutation

(2009) Anna Granlund et al.   EXPERIMENTAL PHYSIOLOGY

AMPK in Health and Disease

(2009) Gregory R. Steinberg et al.   PHYSIOLOGICAL REVIEWS

AMPK and PPARδ Agonists Are Exercise Mimetics

(2008) Vihang A. Narkar et al.   CELL