Interplay of the iron-regulated metastasis suppressor NDRG1 with epidermal growth factor receptor (EGFR) and oncogenic signaling
出版年份 2017 全文链接
标题
Interplay of the iron-regulated metastasis suppressor NDRG1 with epidermal growth factor receptor (EGFR) and oncogenic signaling
作者
关键词
-
出版物
JOURNAL OF BIOLOGICAL CHEMISTRY
Volume 292, Issue 31, Pages 12772-12782
出版商
American Society for Biochemistry & Molecular Biology (ASBMB)
发表日期
2017-06-15
DOI
10.1074/jbc.r117.776393
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Metals and metastasis: Exploiting the role of metals in cancer metastasis to develop novel anti-metastatic agents
- (2017) Leyla Fouani et al. PHARMACOLOGICAL RESEARCH
- NDRG1 overexpression promotes the progression of esophageal squamous cell carcinoma through modulating Wnt signaling pathway
- (2016) Runna Ai et al. CANCER BIOLOGY & THERAPY
- EGFR regulates iron homeostasis to promote cancer growth through redistribution of transferrin receptor 1
- (2016) Biao Wang et al. CANCER LETTERS
- Targeting of PYK2 Synergizes with EGFR Antagonists in Basal-like TNBC and Circumvents HER3-Associated Resistance via the NEDD4–NDRG1 Axis
- (2016) Nandini Verma et al. CANCER RESEARCH
- Truncation, modification, and optimization of MIG6segment 2 peptide to target lung cancer-related EGFR
- (2016) Xiao-Dong Yu et al. COMPUTATIONAL BIOLOGY AND CHEMISTRY
- The novel thiosemicarbazone, di-2-pyridylketone 4-cyclohexyl-4-methyl-3-thiosemicarbazone (DpC), inhibits neuroblastoma growth in vitro and in vivo via multiple mechanisms
- (2016) Zhu-Ling Guo et al. Journal of Hematology & Oncology
- Haem-dependent dimerization of PGRMC1/Sigma-2 receptor facilitates cancer proliferation and chemoresistance
- (2016) Yasuaki Kabe et al. Nature Communications
- PGRMC1 regulation by phosphorylation: potential new insights in controlling biological activity
- (2016) Michael A. Cahill et al. Oncotarget
- PTENInhibits Cell Proliferation, Promotes Cell Apoptosis, and Induces Cell Cycle Arrest via Downregulating the PI3K/AKT/hTERTPathway in Lung Adenocarcinoma A549 Cells
- (2016) Xiao-Xiao Lu et al. Biomed Research International
- The Metastasis Suppressor, N-MYC Downstream-regulated Gene-1 (NDRG1), Down-regulates the ErbB Family of Receptors to Inhibit Downstream Oncogenic Signaling Pathways
- (2015) Zaklina Kovacevic et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Role of Pgrmc1 in estrogen maintenance of meiotic arrest in zebrafish oocytes through Gper/Egfr
- (2015) J. Aizen et al. JOURNAL OF ENDOCRINOLOGY
- Overexpression of N-myc downstream-regulated gene 1 inhibits human glioma proliferation and invasion via phosphoinositide 3-kinase/AKT pathways
- (2015) WEI MA et al. Molecular Medicine Reports
- Structure and mechanism of activity-based inhibition of the EGF receptor by Mig6
- (2015) Eunyoung Park et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- Structure and mechanism of activity-based inhibition of the EGF receptor by Mig6
- (2015) Eunyoung Park et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- The proto-oncogene c-Src and its downstream signaling pathways are inhibited by the metastasis suppressor, NDRG1
- (2015) Wensheng Liu et al. Oncotarget
- Differential targeting of the cyclin-dependent kinase inhibitor, p21CIP1/WAF1, by chelators with anti-proliferative activity in a range of tumor cell-types
- (2015) Rayan S. Moussa et al. Oncotarget
- Role of ErbB Receptors in Cancer Cell Migration and Invasion
- (2015) Aline Appert-Collin et al. Frontiers in Pharmacology
- The iron chelator Dp44mT inhibits hepatocellular carcinoma metastasis via N-Myc downstream-regulated gene 2 (NDRG2)/gp130/STAT3 pathway
- (2015) Jiabei Wang et al. Oncotarget
- The metastasis suppressor NDRG1 modulates the phosphorylation and nuclear translocation of -catenin through mechanisms involving FRAT1 and PAK4
- (2014) R. Jin et al. JOURNAL OF CELL SCIENCE
- Tyrosine Phosphorylation of Mig6 Reduces Its Inhibition of the Epidermal Growth Factor Receptor
- (2013) Zhihong Wang et al. ACS Chemical Biology
- Dp44mT targets the AKT, TGF-β and ERK pathways via the metastasis suppressor NDRG1 in normal prostate epithelial cells and prostate cancer cells
- (2013) K M Dixon et al. BRITISH JOURNAL OF CANCER
- Metastasis suppressor, NDRG1, mediates its activity through signaling pathways and molecular motors
- (2013) J. Sun et al. CARCINOGENESIS
- NDRG1 functions in LDL receptor trafficking by regulating endosomal recycling and degradation
- (2013) V. Pietiainen et al. JOURNAL OF CELL SCIENCE
- The ErbB/HER family of protein-tyrosine kinases and cancer
- (2013) Robert Roskoski PHARMACOLOGICAL RESEARCH
- N-myc Downstream Regulated 1 (NDRG1) Is Regulated by Eukaryotic Initiation Factor 3a (eIF3a) during Cellular Stress Caused by Iron Depletion
- (2013) Darius J. R. Lane et al. PLoS One
- The Iron-Regulated Metastasis Suppressor NDRG1 Targets NEDD4L, PTEN, and SMAD4 and Inhibits the PI3K and Ras Signaling Pathways
- (2012) Zaklina Kovacevic et al. ANTIOXIDANTS & REDOX SIGNALING
- N-myc downstream regulated gene 1 modulates Wnt-β-catenin signalling and pleiotropically suppresses metastasis
- (2012) Wen Liu et al. EMBO Molecular Medicine
- Src-mediated regulation of E-cadherin and EMT in pancreatic cancer
- (2012) Nagaraj et al. Frontiers in Bioscience-Landmark
- The Iron Chelators Dp44mT and DFO Inhibit TGF-β-induced Epithelial-Mesenchymal Transition via Up-Regulation of N-Myc Downstream-regulated Gene 1 (NDRG1)
- (2012) Zhiqiang Chen et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Novel Second-Generation Di-2-Pyridylketone Thiosemicarbazones Show Synergism with Standard Chemotherapeutics and Demonstrate Potent Activity against Lung Cancer Xenografts after Oral and Intravenous Administration in Vivo
- (2012) David B. Lovejoy et al. JOURNAL OF MEDICINAL CHEMISTRY
- High-resolution genome-wide mapping of HIF-binding sites by ChIP-seq
- (2011) J. Schodel et al. BLOOD
- Antitumor Activity of Metal-Chelating Compound Dp44mT Is Mediated by Formation of a Redox-Active Copper Complex That Accumulates in Lysosomes
- (2011) D. B. Lovejoy et al. CANCER RESEARCH
- The metastasis suppressor, N-myc downstream regulated gene 1 (NDRG1), upregulates p21 via p53-independent mechanisms
- (2011) Zaklina Kovacevic et al. CARCINOGENESIS
- Nitric Oxide Suppresses Tumor Cell Migration through N-Myc Downstream-regulated Gene-1 (NDRG1) Expression
- (2011) Jason R. Hickok et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- KAI1Gene Is Engaged inNDRG1Gene-mediated Metastasis Suppression through the ATF3-NFκB Complex in Human Prostate Cancer
- (2011) Wen Liu et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- EGFR Signaling Promotes TGF -Dependent Renal Fibrosis
- (2011) J. Chen et al. JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY
- Novel Thiosemicarbazone Iron Chelators Induce Up-Regulation and Phosphorylation of the Metastasis Suppressor N-myc Down-Stream Regulated Gene 1: A New Strategy for the Treatment of Pancreatic Cancer
- (2011) Z. Kovacevic et al. MOLECULAR PHARMACOLOGY
- Pgrmc1 (Progesterone Receptor Membrane Component 1) Associates with Epidermal Growth Factor Receptor and Regulates Erlotinib Sensitivity
- (2010) Ikhlas S. Ahmed et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- A two-tiered mechanism of EGFR inhibition by RALT/MIG6 via kinase suppression and receptor degradation
- (2010) Yuri Frosi et al. JOURNAL OF CELL BIOLOGY
- N-myc Downstream Regulated Gene 1/Cap43 Suppresses Tumor Growth and Angiogenesis of Pancreatic Cancer through Attenuation of Inhibitor of B Kinase Expression
- (2009) F. Hosoi et al. CANCER RESEARCH
- Identification of c-Src tyrosine kinase substrates in platelet-derived growth factor receptor signaling
- (2009) Ramars Amanchy et al. Molecular Oncology
- Iron Chelator-Mediated Alterations in Gene Expression: Identification of Novel Iron-Regulated Molecules That Are Molecular Targets of Hypoxia-Inducible Factor-1 and p53
- (2009) F. Saletta et al. MOLECULAR PHARMACOLOGY
- The iron-regulated metastasis suppressor, Ndrg-1: Identification of novel molecular targets
- (2008) Zaklina Kovacevic et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH
- Cap43/NDRG1/Drg-1 is a molecular target for angiogenesis and a prognostic indicator in cervical adenocarcinoma
- (2008) Shin Nishio et al. CANCER LETTERS
- In vitro-targeted gene identification in patients with hepatitis C using a genome-wide microarray technology
- (2008) Susanne Hagist et al. HEPATOLOGY
- Quantitative proteomics and phosphoproteomics reveal novel insights into complexity and dynamics of the EGFR signaling network
- (2008) Sandra Morandell et al. PROTEOMICS
Discover Peeref hubs
Discuss science. Find collaborators. Network.
Join a conversationAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started