Demethylation of induced pluripotent stem cells from type 1 diabetic patients enhances differentiation into functional pancreatic β cells

Human iPS Cell-Derived Insulin Producing Cells Form Vascularized Organoids under the Kidney Capsules of Diabetic Mice

(2015) Sudhanshu P. Raikwar et al.   PLoS One

Lifestyle and Cardiometabolic Risk in Adults with Type 1 Diabetes: A Review

(2014) Catherine Leroux et al.   Canadian Journal of Diabetes

Generation of Functional Human Pancreatic β Cells In Vitro

(2014) Felicia W. Pagliuca et al.   CELL

Efficient Endoderm Induction from Human Pluripotent Stem Cells by Logically Directing Signals Controlling Lineage Bifurcations

(2014) Kyle M. Loh et al.   Cell Stem Cell

Skin deep: from dermal fibroblasts to pancreatic beta cells

(2014) Gohar S. Manzar et al.   IMMUNOLOGIC RESEARCH

Reversal of diabetes with insulin-producing cells derived in vitro from human pluripotent stem cells

(2014) Alireza Rezania et al.   NATURE BIOTECHNOLOGY

Generation of a vascularized and functional human liver from an iPSC-derived organ bud transplant

(2014) Takanori Takebe et al.   Nature Protocols

Generation of multiciliated cells in functional airway epithelia from human induced pluripotent stem cells

(2014) A. L. Firth et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Generation of insulin-producing β-like cells from human iPS cells in a defined and completely xeno-free culture system

(2014) Hussain Md. Shahjalal et al.   Journal of Molecular Cell Biology

Human iPS cell-derived hematopoietic progenitor cells induce T-cell anergy in in vitro-generated alloreactive CD8+ T cells

(2013) E.-M. Kim et al.   BLOOD

Dynamic Chromatin Remodeling Mediated by Polycomb Proteins Orchestrates Pancreatic Differentiation of Human Embryonic Stem Cells

(2013) Ruiyu Xie et al.   Cell Stem Cell

Artificial three-dimensional niches deconstruct pancreas development in vitro

(2013) C. Greggio et al.   DEVELOPMENT

Functional evaluation of ES cell-derived endodermal populations reveals differences between Nodal and Activin A-guided differentiation

(2013) A. E. Chen et al.   DEVELOPMENT

Vascularized and functional human liver from an iPSC-derived organ bud transplant

(2013) Takanori Takebe et al.   NATURE

Cerebral organoids model human brain development and microcephaly

(2013) Madeline A. Lancaster et al.   NATURE

A simple tool to improve pluripotent stem cell differentiation

(2013) Sundari Chetty et al.   NATURE METHODS

Brief demethylation step allows the conversion of adult human skin fibroblasts into insulin-secreting cells

(2013) G. Pennarossa et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Nkx6.1 Is Essential for Maintaining the Functional State of Pancreatic Beta Cells

(2013) Brandon L. Taylor et al.   Cell Reports

Nkx6.1 Controls a Gene Regulatory Network Required for Establishing and Maintaining Pancreatic Beta Cell Identity

(2013) Ashleigh E. Schaffer et al.   PLoS Genetics

Human embryonic stem cell differentiation into insulin secreting β-cells for diabetes

(2012) Bipasha Bose et al.   CELL BIOLOGY INTERNATIONAL

Maturation of Human Embryonic Stem Cell-Derived Pancreatic Progenitors Into Functional Islets Capable of Treating Pre-existing Diabetes in Mice

(2012) A. Rezania et al.   DIABETES

The promise of induced pluripotent stem cells in research and therapy

(2012) Daisy A. Robinton et al.   NATURE

Insulin effects in muscle and adipose tissue

(2011) George Dimitriadis et al.   DIABETES RESEARCH AND CLINICAL PRACTICE

Recent Advances and Prospects in the Differentiation of Pancreatic Cells From Human Embryonic Stem Cells

(2010) J. K. Mfopou et al.   DIABETES

Indolactam V/GLP-1-mediated differentiation of human iPS cells into glucose-responsive insulin-secreting progeny

(2010) T Thatava et al.   GENE THERAPY

Minireview: β-Cell Replacement Therapy for Diabetes in the 21st Century: Manipulation of Cell Fate by Directed Differentiation

(2010) Vijay Yechoor et al.   MOLECULAR ENDOCRINOLOGY

Matrigel: A complex protein mixture required for optimal growth of cell culture

(2010) Chris S. Hughes et al.   PROTEOMICS

Highly efficient differentiation of human ES cells and iPS cells into mature pancreatic insulin-producing cells

(2009) Donghui Zhang et al.   CELL RESEARCH

Generation of pluripotent stem cells from patients with type 1 diabetes

(2009) R. Maehr et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Pancreatic endoderm derived from human embryonic stem cells generates glucose-responsive insulin-secreting cells in vivo

(2008) Evert Kroon et al.   NATURE BIOTECHNOLOGY