Growth-incompetent monomers of human calcitonin lead to a noncanonical direct relationship between peptide concentration and aggregation lag time

Strain-specific Fibril Propagation by an Aβ Dodecamer

(2017) Dexter N. Dean et al.   Scientific Reports

Alzheimer's Disease and the Amyloid-β Peptide

(2017) M. Paul Murphy et al.   JOURNAL OF ALZHEIMERS DISEASE

Crystal Structure of the DFNKF Segment of Human Calcitonin Unveils Aromatic Interactions between Phenylalanines

(2016) Arianna Bertolani et al.   CHEMISTRY-A EUROPEAN JOURNAL

Revisiting supersaturation as a factor determining amyloid fibrillation

(2016) Masatomo So et al.   CURRENT OPINION IN STRUCTURAL BIOLOGY

Understanding the adsorption of salmon calcitonin, antimicrobial peptide AP114 and polymyxin B onto lipid nanocapsules

(2016) Anita Umerska et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

Lipid-based nanoformulations for peptide delivery

(2016) Nada Matougui et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

Structural Biology of Calcitonin: From Aqueous Therapeutic Properties to Amyloid Aggregation

(2016) Kian Kamgar-Parsi et al.   ISRAEL JOURNAL OF CHEMISTRY

Parallelization and improvements of the generalized born model with a simple sWitching function for modern graphics processors

(2016) Evan J. Arthur et al.   JOURNAL OF COMPUTATIONAL CHEMISTRY

Modeling the Effect of Monomer Conformational Change on the Early Stage of Protein Self-Assembly into Fibrils

(2016) Dimo Kashchiev   JOURNAL OF PHYSICAL CHEMISTRY B

Estimation of the lag time in a subsequent monomer addition model for fibril elongation

(2016) Suzanne K. Shoffner et al.   PHYSICAL CHEMISTRY CHEMICAL PHYSICS

The emergence of superstructural order in insulin amyloid fibrils upon multiple rounds of self-seeding

(2016) Weronika Surmacz-Chwedoruk et al.   Scientific Reports

A Comparison of Three Fluorophores for the Detection of Amyloid Fibers and Prefibrillar Oligomeric Assemblies. ThT (Thioflavin T); ANS (1-Anilinonaphthalene-8-sulfonic Acid); and bisANS (4,4′-Dianilino-1,1′-binaphthyl-5,5′-disulfonic Acid)

(2015) Nadine D. Younan et al.   BIOCHEMISTRY

Solution NMR Studies of Recombinant Aβ(1-42): From the Presence of a Micellar Entity to Residual β-Sheet Structure in the Soluble Species

(2015) Marielle Aulikki Wälti et al.   CHEMBIOCHEM

Probing the Sources of the Apparent Irreproducibility of Amyloid Formation: Drastic Changes in Kinetics and a Switch in Mechanism Due to Micellelike Oligomer Formation at Critical Concentrations of IAPP

(2015) Jeffrey R. Brender et al.   JOURNAL OF PHYSICAL CHEMISTRY B

Agitation of amyloid proteins to speed aggregation measured by ThT fluorescence: A call for standardization

(2015) Kiersten M. Batzli et al.   Materials Science & Engineering C-Materials for Biological Applications

On the lag phase in amyloid fibril formation

(2015) Paolo Arosio et al.   PHYSICAL CHEMISTRY CHEMICAL PHYSICS

Inhibitory effects of magnolol and honokiol on human calcitonin aggregation

(2015) Caiao Guo et al.   Scientific Reports

Native metastable prefibrillar oligomers are the most neurotoxic species among amyloid aggregates

(2014) Marco Diociaiuti et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Exploring the Influence of EGCG on the β-Sheet-Rich Oligomers of Human Islet Amyloid Polypeptide (hIAPP1–37) and Identifying Its Possible Binding Sites from Molecular Dynamics Simulation

(2014) Qianqian Wang et al.   PLoS One

Ostwald’s rule of stages governs structural transitions and morphology of dipeptide supramolecular polymers

(2014) Aviad Levin et al.   Nature Communications

Ultrafast propagation of β-amyloid fibrils in oligomeric cloud

(2014) Hirotsugu Ogi et al.   Scientific Reports

A Micellar On-Pathway Intermediate Step Explains the Kinetics of Prion Amyloid Formation

(2014) Erwan Hingant et al.   PLoS Computational Biology

Mucoadhesive intestinal devices for oral delivery of salmon calcitonin

(2013) Vivek Gupta et al.   JOURNAL OF CONTROLLED RELEASE

Toward the Molecular Mechanism(s) by Which EGCG Treatment Remodels Mature Amyloid Fibrils

(2013) Fernando L. Palhano et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Role of aromatic residues in amyloid fibril formation of human calcitonin by solid-state 13C NMR and molecular dynamics simulation

(2013) Hikari Itoh-Watanabe et al.   PHYSICAL CHEMISTRY CHEMICAL PHYSICS

Characterization of the spherical intermediates and fibril formation of hCT in HEPES solution using solid-state 13C-NMR and transmission electron microscopy

(2013) Hikari Itoh-Watanabe et al.   PHYSICAL CHEMISTRY CHEMICAL PHYSICS

Proliferation of amyloid- 42 aggregates occurs through a secondary nucleation mechanism

(2013) S. I. A. Cohen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Fibril formation and toxicity of the non-amyloidogenic rat amylin peptide

(2012) Nathaniel G.N. Milton et al.   MICRON

Aliphatic peptides show similar self-assembly to amyloid core sequences, challenging the importance of aromatic interactions in amyloidosis

(2012) A. Lakshmanan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Misfolded proteins in Alzheimer's disease and type II diabetes

(2011) Alaina S. DeToma et al.   CHEMICAL SOCIETY REVIEWS

NMR Characterization of Monomeric and Oligomeric Conformations of Human Calcitonin and Its Interaction with EGCG

(2011) Rui Huang et al.   JOURNAL OF MOLECULAR BIOLOGY

Dissecting the Kinetic Process of Amyloid Fiber Formation through Asymptotic Analysis

(2011) Liu Hong et al.   JOURNAL OF PHYSICAL CHEMISTRY B

Detection of Strongly Bound Thioflavin T Species in Amyloid Fibrils by Ligand-Detected 1H NMR

(2011) Kevin J. Robbins et al.   Journal of Physical Chemistry Letters

Islet Amyloid Polypeptide, Islet Amyloid, and Diabetes Mellitus

(2011) Per Westermark et al.   PHYSIOLOGICAL REVIEWS

Specific Mutations Alter Fibrillation Kinetics, Fiber Morphologies, and Membrane Interactions of Pentapeptides Derived from Human Calcitonin

(2010) Amit Shtainfeld et al.   BIOCHEMISTRY

Converting the Highly Amyloidogenic Human Calcitonin into a Powerful Fibril Inhibitor by Three-dimensional Structure Homology with a Non-amyloidogenic Analogue

(2010) Giuseppina Andreotti et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

CHARMM: The biomolecular simulation program

(2009) B. R. Brooks et al.   JOURNAL OF COMPUTATIONAL CHEMISTRY

Association of Highly Compact Type II Diabetes Related Islet Amyloid Polypeptide Intermediate Species at Physiological Temperature Revealed by Diffusion NMR Spectroscopy

(2009) Ronald Soong et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Can misfolded proteins be beneficial? The HAMLET case

(2008) Jenny Pettersson-Kastberg et al.   ANNALS OF MEDICINE

Chitosan–aprotinin coated liposomes for oral peptide delivery: Development, characterisation and in vivo evaluation

(2008) Martin Werle et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS