Myostatin inhibits osteoblastic differentiation by suppressing osteocyte-derived exosomal microRNA-218: A novel mechanism in muscle-bone communication

Osteoclast-derived exosomal miR-214-3p inhibits osteoblastic bone formation

(2016) Defang Li et al.   Nature Communications

The Wnt Inhibitor Sclerostin Is Up-regulated by Mechanical Unloading in Osteocytesin Vitro

(2015) Jordan M. Spatz et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Myostatin is a direct regulator of osteoclast differentiation and its inhibition reduces inflammatory joint destruction in mice

(2015) Berno Dankbar et al.   NATURE MEDICINE

The myokine irisin increases cortical bone mass

(2015) Graziana Colaianni et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Sarcopenia and mortality among a population-based sample of community-dwelling older adults

(2015) Justin C. Brown et al.   Journal of Cachexia Sarcopenia and Muscle

Direct Regulation of Osteocytic Connexin 43 Hemichannels through AKT Kinase Activated by Mechanical Stimulation

(2014) Nidhi Batra et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Irisin Enhances Osteoblast DifferentiationIn Vitro

(2014) Graziana Colaianni et al.   International Journal of Endocrinology

A myostatin inhibitor (propeptide-Fc) increases muscle mass and muscle fiber size in aged mice but does not increase bone density or bone strength

(2013) Phonepasong Arounleut et al.   EXPERIMENTAL GERONTOLOGY

The Central Nervous System (CNS)-independent Anti-bone-resorptive Activity of Muscle Contraction and the Underlying Molecular and Cellular Signatures

(2013) Weiping Qin et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Myostatin – The Holy Grail for Muscle, Bone, and Fat?

(2013) B. Buehring et al.   Current Osteoporosis Reports

In vitro and in vivo approaches to study osteocyte biology

(2012) Ivo Kalajzic et al.   BONE

Effects of the activin A–myostatin–follistatin system on aging bone and muscle progenitor cells

(2012) Matthew Bowser et al.   EXPERIMENTAL GERONTOLOGY

miR-218 Directs a Wnt Signaling Circuit to Promote Differentiation of Osteoblasts and Osteomimicry of Metastatic Cancer Cells

(2012) Mohammad Q. Hassan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Extracellular phosphate modulates the effect of 1α,25-dihydroxy vitamin D3 (1,25D) on osteocyte like cells

(2012) Nobuaki Ito et al.   JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY

MicroRNA control of bone formation and homeostasis

(2012) Jane B. Lian et al.   Nature Reviews Endocrinology

Cell line IDG-SW3 replicates osteoblast-to-late-osteocyte differentiation in vitro and accelerates bone formation in vivo

(2011) Stacey M Woo et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Human saliva, plasma and breast milk exosomes contain RNA: uptake by macrophages

(2011) Cecilia Lässer et al.   Journal of Translational Medicine

Matrix-embedded cells control osteoclast formation

(2011) Jinhu Xiong et al.   NATURE MEDICINE

Evidence for osteocyte regulation of bone homeostasis through RANKL expression

(2011) Tomoki Nakashima et al.   NATURE MEDICINE

Sclerostin Stimulates Osteocyte Support of Osteoclast Activity by a RANKL-Dependent Pathway

(2011) Asiri R. Wijenayaka et al.   PLoS One

Bone and muscle loss after spinal cord injury: organ interactions

(2010) Weiping Qin et al.   Annals of the New York Academy of Sciences

Osteocyte Mechanobiology and Pericellular Mechanics

(2010) Christopher R. Jacobs et al.   Annual Review of Biomedical Engineering

A Role for Myokines in Muscle-Bone Interactions

(2010) Mark W. Hamrick   EXERCISE AND SPORT SCIENCES REVIEWS

Regulatory Mechanism of Osteoclastogenesis by RANKL and Wnt Signals

(2010) Naoyuki Takahashi   Frontiers in Bioscience-Landmark

The amazing osteocyte

(2010) Lynda F Bonewald   JOURNAL OF BONE AND MINERAL RESEARCH

Exosomes: Extracellular organelles important in intercellular communication

(2010) Suresh Mathivanan et al.   Journal of Proteomics

Osteocyte Wnt/ -Catenin Signaling Is Required for Normal Bone Homeostasis

(2010) I. Kramer et al.   MOLECULAR AND CELLULAR BIOLOGY

Physical therapy approaches to reduce fall and fracture risk among older adults

(2010) Saija Karinkanta et al.   Nature Reviews Endocrinology

Dendritic processes of osteocytes are mechanotransducers that induce the opening of hemichannels

(2010) S. Burra et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Physiology of Bone Loss

(2010) Bart L. Clarke et al.   RADIOLOGIC CLINICS OF NORTH AMERICA

Evolving Concepts in Neurogenic Osteoporosis

(2010) Weiping Qin et al.   Current Osteoporosis Reports

Disuse Osteopenia

(2010) Susan A. Bloomfield   Current Osteoporosis Reports

Wnt signaling in bone metabolism

(2009) Takuo Kubota et al.   JOURNAL OF BONE AND MINERAL METABOLISM

High Levels of Exosomes Expressing CD63 and Caveolin-1 in Plasma of Melanoma Patients

(2009) Mariantonia Logozzi et al.   PLoS One

Participation in High-Impact Sports Predicts Bone Mineral Density in Senior Olympic Athletes

(2009) Daniel Leigey et al.   Sports Health-A Multidisciplinary Approach

Osteocytes, mechanosensing and Wnt signaling

(2008) Lynda F. Bonewald et al.   BONE

Apoptotic Bodies Convey Activity Capable of Initiating Osteoclastogenesis and Localized Bone Destruction

(2008) Giolanta Kogianni et al.   JOURNAL OF BONE AND MINERAL RESEARCH

A soluble activin Type IIA receptor induces bone formation and improves skeletal integrity

(2008) R. S. Pearsall et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA