Mouse Models of Alzheimer’s Disease

Apolipoprotein E and Sex Bias in Cerebrovascular Aging of Men and Mice

(2016) Caleb E. Finch et al.   TRENDS IN NEUROSCIENCES

Current and future implications of basic and translational research on amyloid-β peptide production and removal pathways

(2015) C. Bohm et al.   MOLECULAR AND CELLULAR NEUROSCIENCE

Insulin resistance in Alzheimer disease: Is heme oxygenase-1 an Achille's heel?

(2015) Eugenio Barone et al.   NEUROBIOLOGY OF DISEASE

Elevated risk of type 2 diabetes for development of Alzheimer disease: A key role for oxidative stress in brain

(2014) D. Allan Butterfield et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Animal models of dementia and cognitive dysfunction

(2014) Neha et al.   LIFE SCIENCES

Two Phase 3 Trials of Bapineuzumab in Mild-to-Moderate Alzheimer's Disease

(2014) Stephen Salloway et al.   NEW ENGLAND JOURNAL OF MEDICINE

Targeting ApoE4/ApoE receptor LRP1 in Alzheimer's disease

(2013) Henna Martiskainen et al.   EXPERT OPINION ON THERAPEUTIC TARGETS

Modeling Alzheimer’s disease in transgenic rats

(2013) Sonia Do Carmo et al.   Molecular Neurodegeneration

Apolipoprotein E and Alzheimer disease: risk, mechanisms and therapy

(2013) Chia-Chen Liu et al.   Nature Reviews Neurology

Genetic mouse models of brain ageing and Alzheimer's disease

(2013) Andras Bilkei-Gorzo   PHARMACOLOGY & THERAPEUTICS

A Reliable Way to Detect Endogenous Murine β-Amyloid

(2013) Andrew F. Teich et al.   PLoS One

New animal models of Alzheimer’s disease that display insulin desensitization in the brain

(2013) Chong Gao et al.   REVIEWS IN THE NEUROSCIENCES

Alzheimer Mechanisms and Therapeutic Strategies

(2012) Yadong Huang et al.   CELL

Apolipoprotein E3 (ApoE3) but Not ApoE4 Protects against Synaptic Loss through Increased Expression of Protein Kinase Cϵ

(2012) Abhik Sen et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Apolipoprotein E, Especially Apolipoprotein E4, Increases the Oligomerization of Amyloid   Peptide

(2012) T. Hashimoto et al.   JOURNAL OF NEUROSCIENCE

The Apolipoprotein E (APOE) Gene Appears Functionally Monomorphic in Chimpanzees (Pan troglodytes)

(2012) Annick M. McIntosh et al.   PLoS One

Mouse models of Alzheimer's disease

(2011) Alicia M. Hall et al.   BRAIN RESEARCH BULLETIN

Recent rodent models for Alzheimer’s disease: clinical implications and basic research

(2011) Nady Braidy et al.   JOURNAL OF NEURAL TRANSMISSION

The amyloid cascade hypothesis for Alzheimer's disease: an appraisal for the development of therapeutics

(2011) Eric Karran et al.   NATURE REVIEWS DRUG DISCOVERY

Accelerating drug discovery for Alzheimer's disease: best practices for preclinical animal studies

(2011) Diana W Shineman et al.   Alzheimers Research & Therapy

Alzheimer's Disease

(2010) Henry W. Querfurth et al.   NEW ENGLAND JOURNAL OF MEDICINE

Divergence of human and mouse brain transcriptome highlights Alzheimer disease pathways

(2010) Jeremy A. Miller et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Apolipoprotein E: From lipid transport to neurobiology

(2010) Paul S. Hauser et al.   PROGRESS IN LIPID RESEARCH

Decreased Clearance of CNS  -Amyloid in Alzheimer's Disease

(2010) K. G. Mawuenyega et al.   SCIENCE

Genome-wide association study identifies variants at CLU and CR1 associated with Alzheimer's disease

(2009) Jean-Charles Lambert et al.   NATURE GENETICS

Genome-wide association study identifies variants at CLU and PICALM associated with Alzheimer's disease

(2009) Denise Harold et al.   NATURE GENETICS

Apolipoprotein E and its receptors in Alzheimer's disease: pathways, pathogenesis and therapy

(2009) Guojun Bu   NATURE REVIEWS NEUROSCIENCE

Gene Therapy Using Adeno-Associated Virus Vectors

(2008) S. Daya et al.   CLINICAL MICROBIOLOGY REVIEWS

Reassessing the amyloid cascade hypothesis of Alzheimer's disease

(2008) Sanjay W. Pimplikar   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY