标题
Cognitive Decline in Preclinical Alzheimer’s Disease: Amyloid-Beta versus Tauopathy
作者
关键词
-
出版物
JOURNAL OF ALZHEIMERS DISEASE
Volume 61, Issue 1, Pages 265-281
出版商
IOS Press
发表日期
2017-11-15
DOI
10.3233/jad-170490
参考文献
相关参考文献
注意：仅列出部分参考文献，下载原文获取全部文献信息。- Reductions in Amyloid-β-Derived Neuroinflammation, with Minocycline, Restore Cognition but do not Significantly Affect Tau Hyperphosphorylation
- (2017) Anna Parachikova et al. JOURNAL OF ALZHEIMERS DISEASE
- Drug treatments in Alzheimers disease
- (2016) R. Briggs et al. CLINICAL MEDICINE
- Old and new acetylcholinesterase inhibitors for Alzheimer’s disease
- (2016) Daniela Galimberti et al. EXPERT OPINION ON INVESTIGATIONAL DRUGS
- Gamma frequency entrainment attenuates amyloid load and modifies microglia
- (2016) Hannah F. Iaccarino et al. NATURE
- Linalool reverses neuropathological and behavioral impairments in old triple transgenic Alzheimer's mice
- (2016) Angélica Maria Sabogal-Guáqueta et al. NEUROPHARMACOLOGY
- Long-term exposure to ELF-MF ameliorates cognitive deficits and attenuates tau hyperphosphorylation in 3xTg AD mice
- (2016) Yu Hu et al. NEUROTOXICOLOGY
- The Role of Amyloid-β Oligomers in Toxicity, Propagation, and Immunotherapy
- (2016) Urmi Sengupta et al. EBioMedicine
- Role of Liver X Receptor in AD Pathophysiology
- (2016) Adrián G. Sandoval-Hernández et al. PLoS One
- Long-term Dantrolene Treatment Reduced Intraneuronal Amyloid in Aged Alzheimer Triple Transgenic Mice
- (2015) Zhen Wu et al. ALZHEIMER DISEASE & ASSOCIATED DISORDERS
- Human neural stem cells improve cognition and promote synaptic growth in two complementary transgenic models of Alzheimer's disease and neuronal loss
- (2015) Rahasson R. Ager et al. HIPPOCAMPUS
- Liver X Receptor Agonist Modifies the DNA Methylation Profile of Synapse and Neurogenesis-Related Genes in the Triple Transgenic Mouse Model of Alzheimer’s Disease
- (2015) A. G. Sandoval-Hernández et al. JOURNAL OF MOLECULAR NEUROSCIENCE
- Short-term modern life-like stress exacerbates Aβ-pathology and synapse loss in 3xTg-AD mice
- (2015) David Baglietto-Vargas et al. JOURNAL OF NEUROCHEMISTRY
- Colony-stimulating factor 1 receptor inhibition prevents microglial plaque association and improves cognition in 3xTg-AD mice
- (2015) Nabil N. Dagher et al. Journal of Neuroinflammation
- Neuroinflammatory Signals in Alzheimer Disease and APP/PS1 Transgenic Mice
- (2015) Irene López-González et al. JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY
- Tau Immunotherapy Modulates Both Pathological Tau and Upstream Amyloid Pathology in an Alzheimer's Disease Mouse Model
- (2015) D. L. Castillo-Carranza et al. JOURNAL OF NEUROSCIENCE
- Cyclin-Dependent kinase 5 targeting prevents β-Amyloid aggregation involving glycogen synthase kinase 3β and phosphatases
- (2015) John Fredy Castro-Alvarez et al. JOURNAL OF NEUROSCIENCE RESEARCH
- Ceftriaxone ameliorates tau pathology and cognitive decline via restoration of glial glutamate transporter in a mouse model of Alzheimer's disease
- (2015) Joannee Zumkehr et al. NEUROBIOLOGY OF AGING
- AF710B, a Novel M1/σ1 Agonist with Therapeutic Efficacy in Animal Models of Alzheimer's Disease
- (2015) Abraham Fisher et al. Neurodegenerative Diseases
- An Assessment of Possible Neuropathology and Clinical Relationships in 46 Sporadic Amyotrophic Lateral Sclerosis Patient Autopsies
- (2015) Grant Coan et al. Neurodegenerative Diseases
- Antecedent Disease Is Less Prevalent in Amyotrophic Lateral Sclerosis
- (2015) Cassie S. Mitchell et al. Neurodegenerative Diseases
- The flavonoid quercetin ameliorates Alzheimer's disease pathology and protects cognitive and emotional function in aged triple transgenic Alzheimer's disease model mice
- (2015) Angélica Maria Sabogal-Guáqueta et al. NEUROPHARMACOLOGY
- Seeking homeostasis: temporal trends in respiration, oxidation, and calcium in SOD1 G93A Amyotrophic Lateral Sclerosis mice
- (2015) Cameron W. Irvin et al. Frontiers in Cellular Neuroscience
- State of the field: An informatics-based systematic review of the SOD1-G93A amyotrophic lateral sclerosis transgenic mouse model
- (2015) Renaid B. Kim et al. Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration
- The Effects of Soluble A.β Oligomers on Neurodegeneration in Alzheimer's Disease
- (2015) Jonathan Brouillette CURRENT PHARMACEUTICAL DESIGN
- Lenti-GDNF Gene Therapy Protects Against Alzheimer's Disease-Like Neuropathology in 3xTg-AD Mice and MC65 Cells
- (2014) Susana Revilla et al. CNS Neuroscience & Therapeutics
- Passive immunization targeting the N-terminal projection domain of tau decreases tau pathology and improves cognition in a transgenic mouse model of Alzheimer disease and tauopathies
- (2014) Chun-ling Dai et al. JOURNAL OF NEURAL TRANSMISSION
- Insulin sensitizers improve learning and attenuate tau hyperphosphorylation and neuroinflammation in 3xTg-AD mice
- (2014) Yang Yu et al. JOURNAL OF NEURAL TRANSMISSION
- Down-regulation of serum gonadotropins but not estrogen replacement improves cognition in aged-ovariectomized 3xTg AD female mice
- (2014) Russell Palm et al. JOURNAL OF NEUROCHEMISTRY
- Administration of a selective β2 adrenergic receptor antagonist exacerbates neuropathology and cognitive deficits in a mouse model of Alzheimer's disease
- (2014) Caterina Branca et al. NEUROBIOLOGY OF AGING
- Sleep deprivation impairs memory, tau metabolism, and synaptic integrity of a mouse model of Alzheimer's disease with plaques and tangles
- (2014) Antonio Di Meco et al. NEUROBIOLOGY OF AGING
- High-fat diet-induced memory impairment in triple-transgenic Alzheimer's disease (3xTgAD) mice is independent of changes in amyloid and tau pathology
- (2014) Elysse M. Knight et al. NEUROBIOLOGY OF AGING
- The Intersection of Amyloid Beta and Tau at Synapses in Alzheimer’s Disease
- (2014) Tara L. Spires-Jones et al. NEURON
- Maternal High-Fat Diet Worsens Memory Deficits in the Triple-Transgenic (3xTgAD) Mouse Model of Alzheimer’s Disease
- (2014) Sarah A. L. Martin et al. PLoS One
- Physiological and pathological phosphorylation of tau by Cdk5
- (2014) Taeko Kimura et al. Frontiers in Molecular Neuroscience
- Protein phosphorylation in neurodegeneration: friend or foe?
- (2014) Sandra Tenreiro et al. Frontiers in Molecular Neuroscience
- Protein restriction cycles reduce IGF-1 and phosphorylated Tau, and improve behavioral performance in an Alzheimer's disease mouse model
- (2013) Edoardo Parrella et al. AGING CELL
- α7 Nicotinic Receptor Agonist Enhances Cognition in Aged 3xTg-AD Mice with Robust Plaques and Tangles
- (2013) Rodrigo Medeiros et al. AMERICAN JOURNAL OF PATHOLOGY
- Mifepristone Alters Amyloid Precursor Protein Processing to Preclude Amyloid Beta and Also Reduces Tau Pathology
- (2013) David Baglietto-Vargas et al. BIOLOGICAL PSYCHIATRY
- Systemic vaccination with anti-oligomeric monoclonal antibodies improves cognitive function by reducing Aβ deposition and tau pathology in 3xTg-AD mice
- (2013) Suhail Rasool et al. JOURNAL OF NEUROCHEMISTRY
- Intracerebroventricular Streptozotocin Exacerbates Alzheimer-Like Changes of 3xTg-AD Mice
- (2013) Yanxing Chen et al. MOLECULAR NEUROBIOLOGY
- Nonhuman Amyloid Oligomer Epitope Reduces Alzheimer’s-Like Neuropathology in 3xTg-AD Transgenic Mice
- (2013) Suhail Rasool et al. MOLECULAR NEUROBIOLOGY
- Alzheimer disease therapy—moving from amyloid-β to tau
- (2013) Ezio Giacobini et al. Nature Reviews Neurology
- Neuropep-1 ameliorates learning and memory deficits in an Alzheimer's disease mouse model, increases brain-derived neurotrophic factor expression in the brain, and causes reduction of amyloid beta plaques
- (2013) Min-Kyoo Shin et al. NEUROBIOLOGY OF AGING
- Melanocortins protect against progression of Alzheimer's disease in triple-transgenic mice by targeting multiple pathophysiological pathways
- (2013) Daniela Giuliani et al. NEUROBIOLOGY OF AGING
- Endogenous murine tau promotes neurofibrillary tangles in 3xTg-AD mice without affecting cognition
- (2013) David Baglietto-Vargas et al. NEUROBIOLOGY OF DISEASE
- Hydrogen sulfide slows down progression of experimental Alzheimer’s disease by targeting multiple pathophysiological mechanisms
- (2013) Daniela Giuliani et al. NEUROBIOLOGY OF LEARNING AND MEMORY
- Effects of pretraining and water temperature on female rats' performance in the Morris water maze
- (2013) E.M. Anderson et al. PHYSIOLOGY & BEHAVIOR
- Sex-Specific Effects of High Fat Diet on Indices of Metabolic Syndrome in 3xTg-AD Mice: Implications for Alzheimer's Disease
- (2013) Anna M. Barron et al. PLoS One
- Exenatide promotes cognitive enhancement and positive brain metabolic changes in PS1-KI mice but has no effects in 3xTg-AD animals
- (2013) M Bomba et al. Cell Death & Disease
- Neuropathological Alterations in Alzheimer Disease
- (2013) A. Serrano-Pozo et al. Cold Spring Harbor Perspectives in Medicine
- Mercaptoacetamide-based class II HDAC inhibitor lowers Aβ levels and improves learning and memory in a mouse model of Alzheimer's disease
- (2012) You Me Sung et al. EXPERIMENTAL NEUROLOGY
- Tumor necrosis factor-α synthesis inhibitor 3,6′-dithiothalidomide attenuates markers of inflammation, Alzheimer pathology and behavioral deficits in animal models of neuroinflammation and Alzheimer’s disease
- (2012) David Tweedie et al. Journal of Neuroinflammation
- Neurotoxicity and Memory Deficits Induced by Soluble Low-Molecular-Weight Amyloid- 1-42 Oligomers Are Revealed In Vivo by Using a Novel Animal Model
- (2012) J. Brouillette et al. JOURNAL OF NEUROSCIENCE
- Huprine X and Huperzine A Improve Cognition and Regulate Some Neurochemical Processes Related with Alzheimers Disease in Triple Transgenic Mice (3xTg-AD)
- (2012) M. Ratia et al. Neurodegenerative Diseases
- Dantrolene ameliorates cognitive decline and neuropathology in Alzheimer triple transgenic mice
- (2012) Jun Peng et al. NEUROSCIENCE LETTERS
- Inflammation Induced by Infection Potentiates Tau Pathological Features in Transgenic Mice
- (2011) Michael Sy et al. AMERICAN JOURNAL OF PATHOLOGY
- Loss of Muscarinic M1 Receptor Exacerbates Alzheimer's Disease–Like Pathology and Cognitive Decline
- (2011) Rodrigo Medeiros et al. AMERICAN JOURNAL OF PATHOLOGY
- ST101 induces a novel 17kDa APP cleavage that precludes Aβ generation in vivo
- (2011) Kim N. Green et al. ANNALS OF NEUROLOGY
- Seeding of Normal Tau by Pathological Tau Conformers Drives Pathogenesis of Alzheimer-like Tangles
- (2011) Jing L. Guo et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Blocking IL-1 Signaling Rescues Cognition, Attenuates Tau Pathology, and Restores Neuronal -Catenin Pathway Function in an Alzheimer's Disease Model
- (2011) M. Kitazawa et al. JOURNAL OF IMMUNOLOGY
- Brain Oligomeric β-Amyloid but Not Total Amyloid Plaque Burden Correlates With Neuronal Loss and Astrocyte Inflammatory Response in Amyloid Precursor Protein/Tau Transgenic Mice
- (2011) Bibiana DaRocha-Souto et al. JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY
- The Aβ oligomer hypothesis for synapse failure and memory loss in Alzheimer’s disease
- (2011) Sergio T. Ferreira et al. NEUROBIOLOGY OF LEARNING AND MEMORY
- Effects of Dietary Supplementation of Carnosine on Mitochondrial Dysfunction, Amyloid Pathology, and Cognitive Deficits in 3xTg-AD Mice
- (2011) Carlo Corona et al. PLoS One
- Amitriptyline-Mediated Cognitive Enhancement in Aged 3×Tg Alzheimer's Disease Mice Is Associated with Neurogenesis and Neurotrophic Activity
- (2011) Wayne Chadwick et al. PLoS One
- Inducing Autophagy by Rapamycin Before, but Not After, the Formation of Plaques and Tangles Ameliorates Cognitive Deficits
- (2011) Smita Majumder et al. PLoS One
- GSK3 and Alzheimer’s disease: facts and fiction…
- (2011) Anna Kremer Frontiers in Molecular Neuroscience
- Pharmacologic reversal of neurogenic and neuroplastic abnormalities and cognitive impairments without affecting Aβ and tau pathologies in 3xTg-AD mice
- (2010) Julie Blanchard et al. ACTA NEUROPATHOLOGICA
- Methylene Blue Reduces Aβ Levels and Rescues Early Cognitive Deficit by Increasing Proteasome Activity
- (2010) David X. Medina et al. BRAIN PATHOLOGY
- Amyloid oligomers: formation and toxicity of Aβ oligomers
- (2010) Masafumi Sakono et al. FEBS Journal
- Impaired neurogenesis is an early event in the etiology of familial Alzheimer's disease in transgenic mice
- (2010) Michael Demars et al. JOURNAL OF NEUROSCIENCE RESEARCH
- Assessment of spatial memory in mice
- (2010) Sunita Sharma et al. LIFE SCIENCES
- Genetic reduction of striatal-enriched tyrosine phosphatase (STEP) reverses cognitive and cellular deficits in an Alzheimer's disease mouse model
- (2010) Y. Zhang et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Dietary zinc supplementation of 3xTg-AD mice increases BDNF levels and prevents cognitive deficits as well as mitochondrial dysfunction
- (2010) C Corona et al. Cell Death & Disease
- Memantine Improves Cognition and Reduces Alzheimer’s-Like Neuropathology in Transgenic Mice
- (2009) Hilda Martinez-Coria et al. AMERICAN JOURNAL OF PATHOLOGY
- Cerebrospinal Fluid β-Amyloid 42 and Tau Proteins as Biomarkers of Alzheimer-Type Pathologic Changes in the Brain
- (2009) Tero Tapiola et al. ARCHIVES OF NEUROLOGY
- GSK3: A possible link between beta amyloid peptide and tau protein
- (2009) Félix Hernández et al. EXPERIMENTAL NEUROLOGY
- Developmental regulation of tau phosphorylation, tau kinases, and tau phosphatases
- (2009) Yang Yu et al. JOURNAL OF NEUROCHEMISTRY
- Pathology Dynamics Predict Spinal Cord Injury Therapeutic Success
- (2009) Cassie S. Mitchell et al. JOURNAL OF NEUROTRAUMA
- Neural stem cells improve cognition via BDNF in a transgenic model of Alzheimer disease
- (2009) M. Blurton-Jones et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Detailed immunohistochemical characterization of temporal and spatial progression of Alzheimer's disease-related pathologies in male triple-transgenic mice
- (2008) Michael A Mastrangelo et al. BMC NEUROSCIENCE
- Nicotinamide Restores Cognition in Alzheimer's Disease Transgenic Mice via a Mechanism Involving Sirtuin Inhibition and Selective Reduction of Thr231-Phosphotau
- (2008) K. N. Green et al. JOURNAL OF NEUROSCIENCE
- Interplay between Cyclin-Dependent Kinase 5 and Glycogen Synthase Kinase 3 Mediated by Neuregulin Signaling Leads to Differential Effects on Tau Phosphorylation and Amyloid Precursor Protein Processing
- (2008) Y. Wen et al. JOURNAL OF NEUROSCIENCE
- Reducing AD-Like Pathology in 3xTg-AD Mouse Model by DNA Epitope Vaccine — A Novel Immunotherapeutic Strategy
- (2008) Nina Movsesyan et al. PLoS One
Discover Peeref hubs
Discuss science. Find collaborators. Network.
Join a conversationAdd your recorded webinar
Do you already have a recorded webinar? Grow your audience and get more views by easily listing your recording on Peeref.
Upload Now