Evidence that the Human Innate Immune Peptide LL-37 may be a Binding Partner of Amyloid-β and Inhibitor of Fibril Assembly

Neuronally-directed effects of RXR activation in a mouse model of Alzheimer’s disease

(2017) M. M. Mariani et al.   Scientific Reports

The Emerging Role of Innate Immunity in Alzheimer’s Disease

(2016) Deepak Kumar Vijaya Kumar et al.   NEUROPSYCHOPHARMACOLOGY

Amyloid-β peptide protects against microbial infection in mouse and worm models of Alzheimer’s disease

(2016) Deepak Kumar Vijaya Kumar et al.   Science Translational Medicine

Tabersonine Inhibits Amyloid Fibril Formation and Cytotoxicity of Aβ(1–42)

(2015) Tianhan Kai et al.   ACS Chemical Neuroscience

New aspects of the structure and mode of action of the human cathelicidin LL-37 revealed by the intrinsic probep-cyanophenylalanine

(2015) Daniela Xhindoli et al.   BIOCHEMICAL JOURNAL

Human antimicrobial peptide LL-37 induces glial-mediated neuroinflammation

(2015) Moonhee Lee et al.   BIOCHEMICAL PHARMACOLOGY

Alzheimer’s Disease: Lessons Learned from Amyloidocentric Clinical Trials

(2015) Andreas Soejitno et al.   CNS DRUGS

Pancreatic β-Cells Limit Autoimmune Diabetes via an Immunoregulatory Antimicrobial Peptide Expressed under the Influence of the Gut Microbiota

(2015) Jia Sun et al.   IMMUNITY

Validation and Characterization of a Novel Peptide That Binds Monomeric and Aggregated β-Amyloid and Inhibits the Formation of Neurotoxic Oligomers

(2015) Renae K. Barr et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Prevention of sporadic Alzheimer's disease: lessons learned from clinical trials and future directions

(2015) Sandrine Andrieu et al.   LANCET NEUROLOGY

A molecular chaperone breaks the catalytic cycle that generates toxic Aβ oligomers

(2015) Samuel I A Cohen et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Alzheimer's and Parkinson's diseases: The prion concept in relation to assembled A , tau, and  -synuclein

(2015) M. Goedert   SCIENCE

A molecular chaperone breaks the catalytic cycle that generates toxic Aβ oligomers

(2015) Samuel I A Cohen et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

β-Amyloid peptides display protective activity against the human Alzheimer’s disease-associated herpes simplex virus-1

(2014) Karine Bourgade et al.   BIOGERONTOLOGY

Disease-Modifying Anti-Alzheimer's Drugs: Inhibitors of Human Cholinesterases Interfering withβ-Amyloid Aggregation

(2014) Simone Brogi et al.   CNS Neuroscience & Therapeutics

Type 3 diabetes is sporadic Alzheimer׳s disease: Mini-review

(2014) Suzanne M. de la Monte   EUROPEAN NEUROPSYCHOPHARMACOLOGY

1 ,25-Dihydroxyvitamin D3 Reduces Cerebral Amyloid-  Accumulation and Improves Cognition in Mouse Models of Alzheimer's Disease

(2014) M. R. Durk et al.   JOURNAL OF NEUROSCIENCE

Phenylbutyrate is a Multifaceted Drug that Exerts Neuroprotective Effects and Reverses the Alzheimer´s Disease-like Phenotype of a Commonly Used Mouse Model

(2013) Mar Cuadrado-Tejedor et al.   CURRENT PHARMACEUTICAL DESIGN

Label-Free Quantitative Mass Spectrometry Reveals Novel Pathways Involved in LL-37 Expression

(2013) Andreas Cederlund et al.   Journal of Innate Immunity

Proliferation of amyloid- 42 aggregates occurs through a secondary nucleation mechanism

(2013) S. I. A. Cohen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Multifunctional Cholinesterase and Amyloid Beta Fibrillization Modulators. Synthesis and Biological Investigation

(2013) Stefania Butini et al.   ACS Medicinal Chemistry Letters

Alzheimer Mechanisms and Therapeutic Strategies

(2012) Yadong Huang et al.   CELL

Discovery and Structure Activity Relationship of Small Molecule Inhibitors of Toxic β-Amyloid-42 Fibril Formation

(2012) Heiko Kroth et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Neurotoxins released from interferon-gamma-stimulated human astrocytes

(2012) M. Lee et al.   NEUROSCIENCE

Kinetic characterization of amyloid-beta 1–42 aggregation with a multimethodological approach

(2011) Manuela Bartolini et al.   ANALYTICAL BIOCHEMISTRY

Overcoming mass transport limitations to achieve femtomolar detection limits on silicon protein microarrays

(2011) Marina Cretich et al.   ANALYTICAL BIOCHEMISTRY

Acidic Fibroblast Growth Factor (FGF) Potentiates Glial-mediated Neurotoxicity by Activating FGFR2 IIIb Protein

(2011) Moonhee Lee et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Cathelicidins Link the Endocrine and Immune Systems

(2010) Matthew L. Mayer et al.   Cell Host & Microbe

Depletion of GSH in glial cells induces neurotoxicity: relevance to aging and degenerative neurological diseases

(2010) Moonhee Lee et al.   FASEB JOURNAL

The Alzheimer's Disease-Associated Amyloid β-Protein Is an Antimicrobial Peptide

(2010) Stephanie J. Soscia et al.   PLoS One

Decreased Clearance of CNS  -Amyloid in Alzheimer's Disease

(2010) K. G. Mawuenyega et al.   SCIENCE

Phenylbutyrate Induces Antimicrobial Peptide Expression

(2009) J. Steinmann et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Surface plasmon resonance imaging for affinity-based biosensors

(2009) Simona Scarano et al.   BIOSENSORS & BIOELECTRONICS

Vitamin D3 Induces Autophagy in Human Monocytes/Macrophages via Cathelicidin

(2009) Jae-Min Yuk et al.   Cell Host & Microbe

CE can identify small molecules that selectively target soluble oligomers of amyloid β protein and display antifibrillogenic activity

(2009) Raffaella Colombo et al.   ELECTROPHORESIS

Systems biology evaluation of immune responses induced by human host defence peptide LL-37 in mononuclear cells

(2009) Neeloffer Mookherjee et al.   Molecular BioSystems

The chemistry and biology of LL-37

(2009) Matthew F. Burton et al.   NATURAL PRODUCT REPORTS

Sonication of proteins causes formation of aggregates that resemble amyloid

(2004) Peter B. Stathopulos et al.   PROTEIN SCIENCE