Lipid droplet remodelling and reduced muscle ceramides following sprint interval and moderate-intensity continuous exercise training in obese males

Muscle sphingolipids during rest and exercise: a C18:0 signature for insulin resistance in humans

(2016) Bryan C. Bergman et al.   DIABETOLOGIA

Skeletal muscle and plasma lipidomic signatures of insulin resistance and overweight/obesity in humans

(2016) Katherine T. Tonks et al.   Obesity

mTORC2 and AMPK differentially regulate muscle triglyceride content via Perilipin 3

(2016) Maximilian Kleinert et al.   Molecular Metabolism

Perilipin 5 fine-tunes lipid oxidation to metabolic demand and protects against lipotoxicity in skeletal muscle

(2016) Claire Laurens et al.   Scientific Reports

ATGL-mediated triglyceride turnover and the regulation of mitochondrial capacity in skeletal muscle

(2015) Ruth C. R. Meex et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Piecing together the puzzle of perilipin proteins and skeletal muscle lipolysis

(2015) Rebecca E.K. MacPherson et al.   Applied Physiology Nutrition and Metabolism

Fatty Acid Trafficking in Starved Cells: Regulation by Lipid Droplet Lipolysis, Autophagy, and Mitochondrial Fusion Dynamics

(2015) Angelika S. Rambold et al.   DEVELOPMENTAL CELL

Changes in mitochondrial perilipin 3 and perilipin 5 protein content in rat skeletal muscle following endurance training and acute stimulated contraction

(2015) S. V. Ramos et al.   EXPERIMENTAL PHYSIOLOGY

Perilipin 3 Differentially Regulates Skeletal Muscle Lipid Oxidation in Active, Sedentary, and Type 2 Diabetic Males

(2015) Jeffrey D. Covington et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Sprint interval and moderate-intensity continuous training have equal benefits on aerobic capacity, insulin sensitivity, muscle capillarisation and endothelial eNOS/NAD(P)Hoxidase protein ratio in obese men

(2015) Matthew Cocks et al.   JOURNAL OF PHYSIOLOGY-LONDON

Ceramides – Lipotoxic Inducers of Metabolic Disorders

(2015) Bhagirath Chaurasia et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

Skeletal Muscle Perilipin 3 and Coatomer Proteins Are Increased following Exercise and Are Associated with Fat Oxidation

(2014) Jeffrey D. Covington et al.   PLoS One

PLIN5 deletion remodels intracellular lipid composition and causes insulin resistance in muscle

(2014) Rachael R. Mason et al.   Molecular Metabolism

Overexpression of PLIN5 in skeletal muscle promotes oxidative gene expression and intramyocellular lipid content without compromising insulin sensitivity

(2013) M. Bosma et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

Skeletal muscle mitochondrial and lipid droplet content assessed with standardized grid sizes for stereology

(2013) Nicholas T. Broskey et al.   JOURNAL OF APPLIED PHYSIOLOGY

Endurance Exercise Training Up-Regulates Lipolytic Proteins and Reduces Triglyceride Content in Skeletal Muscle of Obese Subjects

(2013) Katie Louche et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Endurance Training Modulates Intramyocellular Lipid Compartmentalization and Morphology in Skeletal Muscle of Lean and Obese Women

(2013) Michaela C. Devries et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Plasma lipid profiling in a large population-based cohort

(2013) Jacquelyn M. Weir et al.   JOURNAL OF LIPID RESEARCH

Prolonged exercise training increases intramuscular lipid content and perilipin 2 expression in type I muscle fibers of patients with type 2 diabetes

(2012) C. S. Shaw et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Effect of short-term exercise training on intramyocellular lipid content

(2012) Sudip Bajpeyi et al.   Applied Physiology Nutrition and Metabolism

Perilipin family (PLIN) proteins in human skeletal muscle: the effect of sex, obesity, and endurance training

(2012) Sandra J. Peters et al.   Applied Physiology Nutrition and Metabolism

Mechanisms for Insulin Resistance: Common Threads and Missing Links

(2012) Varman T. Samuel et al.   CELL

Perilipin 2 Improves Insulin Sensitivity in Skeletal Muscle Despite Elevated Intramuscular Lipid Levels

(2012) M. Bosma et al.   DIABETES

Localisation and composition of skeletal muscle diacylglycerol predicts insulin resistance in humans

(2012) B. C. Bergman et al.   DIABETOLOGIA

Preferential utilization of perilipin 2-associated intramuscular triglycerides during 1 h of moderate-intensity endurance-type exercise

(2012) S. O. Shepherd et al.   EXPERIMENTAL PHYSIOLOGY

Perilipin 5, a Lipid Droplet-binding Protein, Protects Heart from Oxidative Burden by Sequestering Fatty Acid from Excessive Oxidation

(2012) Kenta Kuramoto et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

PPARγ coactivator-1α contributes to exercise-induced regulation of intramuscular lipid droplet programming in mice and humans

(2012) Timothy R. Koves et al.   JOURNAL OF LIPID RESEARCH

Sprint interval and traditional endurance training increase net intramuscular triglyceride breakdown and expression of perilipin 2 and 5

(2012) S. O. Shepherd et al.   JOURNAL OF PHYSIOLOGY-LONDON

Physiological adaptations to low-volume, high-intensity interval training in health and disease

(2012) Martin J. Gibala et al.   JOURNAL OF PHYSIOLOGY-LONDON

Sprint interval and endurance training are equally effective in increasing muscle microvascular density and eNOS content in sedentary males

(2012) Matthew Cocks et al.   JOURNAL OF PHYSIOLOGY-LONDON

Revisiting the diacylglycerol-induced insulin resistance hypothesis

(2012) F. Amati   Obesity Reviews

Skeletal Muscle Triglycerides, Diacylglycerols, and Ceramides in Insulin Resistance: Another Paradox in Endurance-Trained Athletes?

(2011) F. Amati et al.   DIABETES

Effects of weight loss and exercise on insulin resistance, and intramyocellular triacylglycerol, diacylglycerol and ceramide

(2011) J. J. Dubé et al.   DIABETOLOGIA

The lipid droplet coat protein perilipin 5 also localizes to muscle mitochondria

(2011) Madeleen Bosma et al.   HISTOCHEMISTRY AND CELL BIOLOGY

Perilipin 5, a lipid droplet-associated protein, provides physical and metabolic linkage to mitochondria

(2011) Hong Wang et al.   JOURNAL OF LIPID RESEARCH

Proteome of Skeletal Muscle Lipid Droplet Reveals Association with Mitochondria and Apolipoprotein A-I

(2011) Huina Zhang et al.   JOURNAL OF PROTEOME RESEARCH

Increased intramuscular lipid synthesis and low saturation relate to insulin sensitivity in endurance-trained athletes

(2010) Bryan C. Bergman et al.   JOURNAL OF APPLIED PHYSIOLOGY

Interactions of Perilipin-5 (Plin5) with Adipose Triglyceride Lipase

(2010) James G. Granneman et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Skeletal Muscle Lipase Content and Activity in Obesity and Type 2 Diabetes

(2010) Johan W. E. Jocken et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Skeletal Muscle Lipogenic Protein Expression Is Not Different between Lean and Obese Individuals: A Potential Factor in Ceramide Accumulation

(2009) A. Brianne Thrush et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Influence of Gender, Obesity, and Muscle Lipase Activity on Intramyocellular Lipids in Sedentary Individuals

(2009) Cedric Moro et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Exercise-induced alterations in intramyocellular lipids and insulin resistance: the athlete's paradox revisited

(2008) John J. Dubé et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Human skeletal muscle ceramide content is not a major factor in muscle insulin sensitivity

(2008) M. Skovbro et al.   DIABETOLOGIA

Similar metabolic adaptations during exercise after low volume sprint interval and traditional endurance training in humans

(2007) Kirsten A. Burgomaster et al.   JOURNAL OF PHYSIOLOGY-LONDON