Z-Guggulsterone Produces Antidepressant-Like Effects in Mice through Activation of the BDNF Signaling Pathway

Amitriptyline induces brain-derived neurotrophic factor (BDNF) mRNA expression through ERK-dependent modulation of multiple BDNF mRNA variants in primary cultured rat cortical astrocytes and microglia

(2016) Kazue Hisaoka-Nakashima et al.   BRAIN RESEARCH

Efficacy of selective serotonin reuptake inhibitors and adverse events: Meta-regression and mediation analysis of placebo-controlled trials

(2016) Michael Barth et al.   BRITISH JOURNAL OF PSYCHIATRY

Depression, Serotonin and Tryptophan

(2016) Liliana Dell'Osso et al.   CURRENT PHARMACEUTICAL DESIGN

Identification of functional farnesoid X receptors in brain neurons

(2016) Chao Huang et al.   FEBS LETTERS

Low-dose lipopolysaccharide (LPS) inhibits aggressive and augments depressive behaviours in a chronic mild stress model in mice

(2016) Yvonne Couch et al.   Journal of Neuroinflammation

Z-Guggulsterone Improves the Scopolamine-Induced Memory Impairments Through Enhancement of the BDNF Signal in C57BL/6J Mice

(2016) Zhuo Chen et al.   NEUROCHEMICAL RESEARCH

Cholesterol overload induces apoptosis in SH-SY5Y human neuroblastoma cells through the up regulation of flotillin-2 in the lipid raft and the activation of BDNF/Trkb signaling

(2016) Yen-Ning Huang et al.   NEUROSCIENCE

Z-guggulsterone negatively controls microglia-mediated neuroinflammation via blocking IκB-α–NF-κB signals

(2016) Chao Huang et al.   NEUROSCIENCE LETTERS

Antidepressant effects of standardized extract of Commiphora mukul Engl. in olfactory bulbectomized rats

(2015) Padmaja Bhimashankar Kalshetti et al.   BRAZILIAN ARCHIVES OF BIOLOGY AND TECHNOLOGY

Trazodone treatment protects neuronal-like cells from inflammatory insult by inhibiting NF-κB, p38 and JNK

(2015) Simona Daniele et al.   CELLULAR SIGNALLING

Neuropeptide Trefoil Factor 3 Reverses Depressive-Like Behaviors by Activation of BDNF-ERK-CREB Signaling in Olfactory Bulbectomized Rats

(2015) Jiali Li et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Neurotrophic factors in depression in response to treatment

(2015) Henriette N. Buttenschøn et al.   JOURNAL OF AFFECTIVE DISORDERS

BDNF as a biomarker for successful treatment of mood disorders: A systematic & quantitative meta-analysis

(2015) Maryna Polyakova et al.   JOURNAL OF AFFECTIVE DISORDERS

Endogenous BDNF augments NMDA receptor phosphorylation in the spinal cord via PLCγ, PKC, and PI3K/Akt pathways during colitis

(2015) Miao Liu et al.   Journal of Neuroinflammation

Inhibition of phosphodiesterase 2 reverses impaired cognition and neuronal remodeling caused by chronic stress

(2015) Ying Xu et al.   NEUROBIOLOGY OF AGING

Effects of acute transcranial direct current stimulation in hot and cold working memory tasks in healthy and depressed subjects

(2015) Marina L. Moreno et al.   NEUROSCIENCE LETTERS

Vortioxetine, a novel antidepressant with multimodal activity: Review of preclinical and clinical data

(2015) Connie Sanchez et al.   PHARMACOLOGY & THERAPEUTICS

The Effect of Recombinant Erythropoietin on Plasma Brain Derived Neurotrophic Factor Levels in Patients with Affective Disorders: A Randomised Controlled Study

(2015) Maj Vinberg et al.   PLoS One

Acute Treatment with a Novel TRPC4/C5 Channel Inhibitor Produces Antidepressant and Anxiolytic-Like Effects in Mice

(2015) Li-Ping Yang et al.   PLoS One

Antidepressant-like effect of Butea superba in mice exposed to chronic mild stress and its possible mechanism of action

(2014) Daishu Mizuki et al.   JOURNAL OF ETHNOPHARMACOLOGY

Effects of Bile Acids and the Bile Acid Receptor FXR Agonist on the Respiratory Rhythm in the In Vitro Brainstem Medulla Slice of Neonatal Sprague-Dawley Rats

(2014) Cong Zhao et al.   PLoS One

Administration of Phytoceramide Enhances Memory and Up-regulates the Expression of pCREB and BDNF in Hippocampus of Mice

(2013) Yeonju Lee et al.   Biomolecules & Therapeutics

The Epigenetic Switches for Neural Development and Psychiatric Disorders

(2013) Jingwen Lv et al.   Journal of Genetics and Genomics

Clinical features and drug induced side effects in early versus late antidepressant responders

(2013) Chiara Fabbri et al.   JOURNAL OF PSYCHIATRIC RESEARCH

Combination antidepressant therapy for major depressive disorder: Speed and probability of remission

(2013) Jonathan W. Stewart et al.   JOURNAL OF PSYCHIATRIC RESEARCH

Monocytes from Depressed Patients Display an Altered Pattern of Response to Endotoxin Challenge

(2013) Lucia Lisi et al.   PLoS One

Where Have I Been? Where Should I Go? Spatial Working Memory on a Radial Arm Maze in a Rat Model of Depression

(2013) Sophie Helene Richter et al.   PLoS One

Antidepressant-Like Effects of Erythropoietin: A Focus on Behavioural and Hippocampal Processes

(2013) Meagan Osborn et al.   PLoS One

Methylphenidate prevents high-fat diet (HFD)-induced learning/memory impairment in juvenile mice

(2013) Melissa M. Kaczmarczyk et al.   PSYCHONEUROENDOCRINOLOGY

BDNF overexpression in mouse hippocampal astrocytes promotes local neurogenesis and elicits anxiolytic-like activities

(2013) G Quesseveur et al.   Translational Psychiatry

Sensitivity of hippocampal 5-HT1A receptors to mild stress in BDNF-deficient mice

(2012) Teresa F. Burke et al.   INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY

Depression, stress, epilepsy and adult neurogenesis

(2011) Steve C. Danzer   EXPERIMENTAL NEUROLOGY

The role of BDNF and its receptors in depression and antidepressant drug action: Reactivation of developmental plasticity

(2010) Eero Castrén et al.   Developmental Neurobiology

Guggulsterone suppresses LPS induced inflammation of human middle ear epithelial cells (HMEEC)

(2010) Jae-Jun Song et al.   INTERNATIONAL JOURNAL OF PEDIATRIC OTORHINOLARYNGOLOGY

The plant sterol guggulsterone attenuates inflammation and immune dysfunction in murine models of inflammatory bowel disease

(2009) Andrea Mencarelli et al.   BIOCHEMICAL PHARMACOLOGY

Effects of guggulsterone isolated from Commiphora mukul in high fat diet induced diabetic rats

(2009) Bhavna Sharma et al.   FOOD AND CHEMICAL TOXICOLOGY

Fuzi polysaccharide-1 produces antidepressant-like effects in mice

(2009) Hua-Cheng Yan et al.   INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY

Acid-Sensing Ion Channel-1a in the Amygdala, a Novel Therapeutic Target in Depression-Related Behavior

(2009) M. W. Coryell et al.   JOURNAL OF NEUROSCIENCE

Conditional Knockout of Brain-Derived Neurotrophic Factor in the Hippocampus Increases Death of Adult-Born Immature Neurons following Traumatic Brain Injury

(2009) Xiang Gao et al.   JOURNAL OF NEUROTRAUMA

Donepezil, an acetylcholinesterase inhibitor, enhances adult hippocampal neurogenesis

(2008) Sadaharu Kotani et al.   CHEMICO-BIOLOGICAL INTERACTIONS