Genomic Insight into the Role of lncRNAs in Cancer Susceptibility

Long Noncoding RNA XIST Promotes Osteosarcoma Progression by Targeting Ras-Related Protein RAP2B via miR-320b

(2018) Gong-Yi Lv et al.   ONCOLOGY RESEARCH

HOTAIR genetic variants are associated with prostate cancer and benign prostate hyperplasia in an Iranian population

(2017) Mohammad Taheri et al.   GENE

H19 promotes the migration and invasion of colon cancer by sponging miR-138 to upregulate the expression of HMGA1

(2017) Qingqiang Yang et al.   INTERNATIONAL JOURNAL OF ONCOLOGY

The long non-coding RNA TP73-AS1 modulates HCC cell proliferation through miR-200a-dependent HMGB1/RAGE regulation

(2017) Shaling Li et al.   JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH

Long non-coding RNA MALAT1 interacts with miR-124 and modulates tongue cancer growth by targeting JAG1

(2017) Tong-Han Zhang et al.   ONCOLOGY REPORTS

Genetic variation of long non-coding RNA TINCR contribute to the susceptibility and progression of colorectal cancer

(2017) Yongbin Zheng et al.   Oncotarget

Long non-coding RNA TUG1 promotes endometrial cancer development via inhibiting miR-299 and miR-34a-5p

(2017) Lifen Liu et al.   Oncotarget

LncRNA CHRF-induced miR-489 loss promotes metastasis of colorectal cancer via TWIST1/EMT signaling pathway

(2017) Youmao Tao et al.   Oncotarget

A feed-forward regulatory loop between androgen receptor and PlncRNA-1 promotes prostate cancer progression

(2016) Ziyu Fang et al.   CANCER LETTERS

Long non-coding RNA: A newly deciphered “code” in prostate cancer

(2016) Ailin Zhang et al.   CANCER LETTERS

Genetic Polymorphisms in the Long Noncoding RNA MIR2052HG Offer a Pharmacogenomic Basis for the Response of Breast Cancer Patients to Aromatase Inhibitor Therapy

(2016) James N. Ingle et al.   CANCER RESEARCH

Programmable RNA Tracking in Live Cells with CRISPR/Cas9

(2016) David A. Nelles et al.   CELL

SNHG16 is regulated by the Wnt pathway in colorectal cancer and affects genes involved in lipid metabolism

(2016) Lise Lotte Christensen et al.   Molecular Oncology

Gene regulatory mechanisms underpinning prostate cancer susceptibility

(2016) Thomas Whitington et al.   NATURE GENETICS

Pancreatic cancer risk variant in LINC00673 creates a miR-1231 binding site and interferes with PTPN11 degradation

(2016) Jian Zheng et al.   NATURE GENETICS

Modulation of long noncoding RNAs by risk SNPs underlying genetic predispositions to prostate cancer

(2016) Haiyang Guo et al.   NATURE GENETICS

A Novel Genetic Variant in Long Non-coding RNA Gene NEXN-AS1 is Associated with Risk of Lung Cancer

(2016) Hua Yuan et al.   Scientific Reports

Prevalence of the HOXB13 G84E germline mutation in British men and correlation with prostate cancer risk, tumour characteristics and clinical outcomes

(2015) Z. Kote-Jarai et al.   ANNALS OF ONCOLOGY

CTCF cooperates with noncoding RNA MYCNOS to promote neuroblastoma progression through facilitating MYCN expression

(2015) X Zhao et al.   ONCOGENE

Transcription factor trapping by RNA in gene regulatory elements

(2015) A. A. Sigova et al.   SCIENCE

A Large-Scale Analysis of Genetic Variants within Putative miRNA Binding Sites in Prostate Cancer

(2015) S. Stegeman et al.   Cancer Discovery

The lncRNAs PCGEM1 and PRNCR1 are not implicated in castration resistant prostate cancer

(2015) John R. Prensner et al.   Oncotarget

HOXB13 G84E–related Familial Prostate Cancers

(2014) Steven C. Smith et al.   AMERICAN JOURNAL OF SURGICAL PATHOLOGY

PCAT-1 , a Long Noncoding RNA, Regulates BRCA2 and Controls Homologous Recombination in Cancer

(2014) John R. Prensner et al.   CANCER RESEARCH

A prostate cancer susceptibility allele at 6q22 increases RFX6 expression by modulating HOXB13 chromatin binding

(2014) Qilai Huang et al.   NATURE GENETICS

lncRNASNP: a database of SNPs in lncRNAs and their potential functions in human and mouse

(2014) Jing Gong et al.   NUCLEIC ACIDS RESEARCH

Long noncoding RNAs and prostate carcinogenesis: the missing ‘linc’?

(2014) Anna L. Walsh et al.   TRENDS IN MOLECULAR MEDICINE

The Long Non-Coding RNA PCAT-1 Promotes Prostate Cancer Cell Proliferation through cMyc

(2014) John R. Prensner et al.   NEOPLASIA

Long noncoding RNAs: New players in prostate cancer

(2013) Wen Cheng et al.   CANCER LETTERS

Androgen-responsive long noncoding RNA CTBP1-AS promotes prostate cancer

(2013) Ken-ichi Takayama et al.   EMBO JOURNAL

lncRNA-dependent mechanisms of androgen-receptor-regulated gene activation programs

(2013) Liuqing Yang et al.   NATURE

The long noncoding RNA SChLAP1 promotes aggressive prostate cancer and antagonizes the SWI/SNF complex

(2013) John R Prensner et al.   NATURE GENETICS

Association between lncrna PCGEM1 polymorphisms and prostate cancer risk

(2013) Y Xue et al.   PROSTATE CANCER AND PROSTATIC DISEASES

Long noncoding RNA: an emerging paradigm of cancer research

(2013) Man-Tang Qiu et al.   TUMOR BIOLOGY

Human Disease-Associated Genetic Variation Impacts Large Intergenic Non-Coding RNA Expression

(2013) Vinod Kumar et al.   PLoS Genetics

PCA3 noncoding RNA is involved in the control of prostate-cancer cell survival and modulates androgen receptor signaling

(2012) Luciana Bueno Ferreira et al.   BMC CANCER

The GENCODE v7 catalog of human long noncoding RNAs: Analysis of their gene structure, evolution, and expression

(2012) T. Derrien et al.   GENOME RESEARCH

Germline Mutations inHOXB13and Prostate-Cancer Risk

(2012) Charles M. Ewing et al.   NEW ENGLAND JOURNAL OF MEDICINE

Mice Lacking a Myc Enhancer That Includes Human SNP rs6983267 Are Resistant to Intestinal Tumors

(2012) I. K. Sur et al.   SCIENCE

Characterization of novel antisense HIF-1α transcripts in human cancers

(2011) Davide Bertozzi et al.   CELL CYCLE

Transcriptome sequencing across a prostate cancer cohort identifies PCAT-1, an unannotated lincRNA implicated in disease progression

(2011) John R Prensner et al.   NATURE BIOTECHNOLOGY

Principles for the post-GWAS functional characterization of cancer risk loci

(2011) Matthew L Freedman et al.   NATURE GENETICS

Molecular Interplay of the Noncoding RNA ANRIL and Methylated Histone H3 Lysine 27 by Polycomb CBX7 in Transcriptional Silencing of INK4a

(2010) Kyoko L. Yap et al.   MOLECULAR CELL

Annotating non-coding regions of the genome

(2010) Roger P. Alexander et al.   NATURE REVIEWS GENETICS

Noncoding RNA Gas5 Is a Growth Arrest- and Starvation-Associated Repressor of the Glucocorticoid Receptor

(2010) T. Kino et al.   Science Signaling

ncRAN, a Newly Identified Long Noncoding RNA, Enhances Human Bladder Tumor Growth, Invasion, and Survival

(2010) Yuyan Zhu et al.   UROLOGY

The 8q24 cancer risk variant rs6983267 shows long-range interaction with MYC in colorectal cancer

(2009) Mark M Pomerantz et al.   NATURE GENETICS

The common colorectal cancer predisposition SNP rs6983267 at chromosome 8q24 confers potential to enhanced Wnt signaling

(2009) Sari Tuupanen et al.   NATURE GENETICS

Human genetic variation and its contribution to complex traits

(2009) Kelly A. Frazer et al.   NATURE REVIEWS GENETICS

Many human large intergenic noncoding RNAs associate with chromatin-modifying complexes and affect gene expression

(2009) Ahmad M. Khalil et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Polymorphisms in the H19 Gene and the Risk of Bladder Cancer

(2008) Gerald W. Verhaegh et al.   EUROPEAN UROLOGY

Epigenetic silencing of tumour suppressor gene p15 by its antisense RNA

(2008) Wenqiang Yu et al.   NATURE

Systematic assessment of copy number variant detection via genome-wide SNP genotyping

(2008) Gregory M Cooper et al.   NATURE GENETICS

Genome-wide association studies for complex traits: consensus, uncertainty and challenges

(2008) Mark I. McCarthy et al.   NATURE REVIEWS GENETICS

GAS5, a non-protein-coding RNA, controls apoptosis and is downregulated in breast cancer

(2008) M Mourtada-Maarabouni et al.   ONCOGENE