Article
Agriculture, Multidisciplinary
Junzhe Yu, Na Hu, Liran Hou, Fangxue Hang, Kai Li, Caifeng Xie
Summary: This study investigated the properties of water-soluble chitosan derivatives and found that the degree of deacetylation of chitosan had a significant effect on its structure, composition, and properties. Mannose incorporation enhanced the antimicrobial and antioxidant activities of chitosan. The results suggest that these chitosan derivatives could be used in various applications.
JOURNAL OF THE SCIENCE OF FOOD AND AGRICULTURE
(2023)
Article
Polymer Science
Nguyen Van Hoa, Nguyen Thi Hong Vuong, Nguyen Cong Minh, Hoang Ngoc Cuong, Trang Si Trung
Summary: The study demonstrates that CSNs prepared from squid pen chitosan with small size and excellent antibacterial activity have high potential applications in various fields.
Review
Biochemistry & Molecular Biology
Shijie (Gabriel) Kou, Linda M. Peters, Michael R. Mucalo
Summary: This article discusses the production methods and different sources of chitosan, focusing on chemical and biological approaches, and suggests lobster cephalothorax as a potential source for industrial scale chitosan preparation.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2021)
Article
Food Science & Technology
Kader Tokatli, Aslihan Demirdoven
Summary: The study found that different chitosans had varying effects on the quality attributes of sweet cherries, with Chitosan-1 exhibiting the highest firmness value at 4 degrees Celsius and Chitosan-2 showing the highest total anthocyanin and total phenolic content under the same conditions. At 20 degrees Celsius, Commercial-1 had the highest antioxidant capacity and ascorbic acid content, while Chitosan-2 displayed the highest total anthocyanin content.
JOURNAL OF FOOD SCIENCE AND TECHNOLOGY-MYSORE
(2021)
Article
Biochemistry & Molecular Biology
Ajay Mittal, Avtar Singh, Rotimi E. Aluko, Soottawat Benjakul
Summary: Chitin was isolated from Pacific white shrimp shell and then deacetylated to prepare chitosan (CS-130-4), which was further grafted with epigallocatechin gallate (EGCG) to yield water-soluble conjugates with enhanced antimicrobial and antioxidant properties. These conjugates, especially CE-8, could be used as natural preservatives in various food products.
JOURNAL OF FOOD BIOCHEMISTRY
(2021)
Article
Chemistry, Applied
Jun Yang, Mingyue Shen, Yu Luo, Ting Wu, Huiliang Wen, Jianhua Xie, Mesona Chinensis
Summary: A novel kind of polyelectrolyte complex hydrogels, MCP-CH, was generated through physical crosslinking, with improved properties and stability as the deacetylation degree (DD) increased, along with enhanced microstructure.
CARBOHYDRATE POLYMERS
(2021)
Review
Engineering, Multidisciplinary
Alia Tasnim Hazmi, Farah B. Ahmad, M. H. Maziati Akmal, Aliza Aini Md Ralib, Fathilah Binti Ali
Summary: This study reviews different experimental procedures for the chemical extraction of fungal chitosan and selects the most effective method using PROMETHEE-GAIA analysis. The microwave-assisted organic acid-alkaline treatment extraction method is found to be the most effective for fungal chitosan extraction.
ALEXANDRIA ENGINEERING JOURNAL
(2023)
Article
Biochemistry & Molecular Biology
Nargess Khosravi, Mahdi Zarabi, Sajjad Shojai, Fatemeh Eshari, Ali A. Moosavi-Movahedi, Mehran Habibi-Rezaei
Summary: The chitin of the Mediterranean flour moth was extracted and converted to chitosan by deacetylation process to produce a new chitosan-based scaffold using polyvinyl alcohol co-electrospinning technique. The properties of the chitosan were analyzed and compared with commercial chitosan. The antimicrobial activity and antioxidant potential of the chitosan were also evaluated.
APPLIED BIOCHEMISTRY AND BIOTECHNOLOGY
(2023)
Review
Polymer Science
Alessandro Pellis, Georg M. Guebitz, Gibson Stephen Nyanhongo
Summary: This review provides an overview of chitosan as an important raw material for various applications and discusses different sources, extraction and conversion techniques, inherent characteristics, and customization methods of chitosan. The review also explores the effects of degree of acetylation, degree of deacetylation, and molecular weight on the properties of chitosan.
Review
Biochemistry & Molecular Biology
Pawel Poznanski, Amir Hameed, Waclaw Orczyk
Summary: Chitosan, derived from chitin, has strong antifungal activity and is biodegradable, biocompatible, and non-toxic. Chitosan nanoparticles can enhance its antifungal activity. Various parameters, such as molecular weight, degree of deacetylation, acetylation pattern, concentration, and protonation of chitosan, affect its antifungal activity and nanoparticle properties. Understanding these parameters is important for designing environmentally friendly plant protection strategies.
Article
Biochemistry & Molecular Biology
Jonathan Carrasco-Sandoval, Mario Aranda, Karem Henriquez-Aedo, Marcos Fernandez, Amparo Lopez-Rubio, Maria Jose Fabra
Summary: This study aimed to investigate the impact of chitosan's molecular weight and degree of deacetylation on the bioaccessibility of quercetin encapsulated in alginate/chitosan-coated zein nanoparticles. The chitosan coating layer resulted in nanoparticulate systems with good stability, high encapsulation efficiency, and increased bioaccessibility of quercetin after in-vitro digestion. The best results were obtained using low molecular weight chitosan and high degree of deacetylation.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2023)
Article
Biochemistry & Molecular Biology
Maciej Spiegel, Tiziana Marino, Mario Prejano, Nino Russo
Summary: This study computationally predicted the antioxidant capability of scutellarein, a flavonoid, by considering its reaction with the OOH radical in both lipid-like and water environments. The results show that scutellarein has a scavenging power similar to Trolox against the hydroperoxyl radical.
Article
Polymer Science
F. Arrouze, J. Desbrieres, S. Lidrissi Hassani, A. Tolaimate
Summary: This study compared the physicochemical characteristics of beta-chitins and chitosans extracted from different parts of cuttlefish bones with that of squid beta-chitin. The source was found to play a significant role in determining the reaction behavior during the extraction of chitin and preparation of chitosan. It was also demonstrated that the large quantities of bones discarded annually by cuttlefish processing units can be valorized by producing beta-chitin and chitosan.
Article
Chemistry, Inorganic & Nuclear
Bradley Russell-Webster, Javi Lopez-Nieto, Khalil A. Abboud, George Christou
Summary: Two new Ce-IV/O2- clusters 1 and 2, containing P-based ligands for the first time, have smaller structural units and exhibit significantly lower HO radical scavenging abilities compared to traditional CeO2 nanoparticles.
DALTON TRANSACTIONS
(2021)
Article
Biochemistry & Molecular Biology
Xian Wu, Yixian Ren, Yue Wen, Sixin Lu, Huihui Li, Honglin Yu, Wenjun Li, Fei Zou
Summary: Mitochondrial dysfunction, oxidative stress, and misfolded protein aggregation are related to the pathogenesis of Parkinson's disease. This study identifies the role of ZKSCAN3 in autophagy-lysosomal dysregulation and demonstrates the potential therapeutic effects of the SIRT1-ZKSCAN3 pathway in PD.
FREE RADICAL BIOLOGY AND MEDICINE
(2022)
Correction
Multidisciplinary Sciences
Thangadurai Thinesh, Ramu Meenatchi, Ramasamy Pasiyappazham, Polpass Arul Jose, Muthamizh Selvan, George Seghal Kiran, Joseph Selvin
Article
Multidisciplinary Sciences
Thangadurai Thinesh, Ramu Meenatchi, Ramasamy Pasiyappazham, Polpass Arul Jose, Muthamizh Selvan, George Seghal Kiran, Joseph Selvin
Review
Biochemistry & Molecular Biology
G. Seghal Kiran, Pasiyappazham Ramasamy, Sivasankari Sekar, Meenatchi Ramu, Saqib Hassan, A. S. Ninawe, Joseph Selvin
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2018)
Article
Environmental Sciences
G. Seghal Kiran, Sivasankari Sekar, Pasiyappazham Ramasamy, Thangadurai Thinesh, Saqib Hassan, Anuj Nishanth Lipton, A. S. Ninawe, Joseph Selvin
MARINE ENVIRONMENTAL RESEARCH
(2018)
Article
Environmental Sciences
Thangadurai Thinesh, Polpass Arul Jose, Pasiyappazham Ramasamy, Ramu Meenatchi, K. Muthamizh Selvan, Joseph Selvin
ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH
(2019)
Article
Fisheries
A. S. Ninawe, S. Sivasankari, P. Ramasamy, G. Seghal Kiran, Joseph Selvin
AQUACULTURE INTERNATIONAL
(2020)
Article
Chemistry, Applied
Pasiyappazham Ramasamy, Sivasankari Sekar, Sivagurunathan Paramasivam, Priyatharsini Suri, Uma Chinnaiyan, Rajesh Singh, Bharath Prasad Tanguturi Raghavaiah, Vidya Devanathadesikan Seshadri
Summary: The study successfully synthesized chitin, chitosan, and sulfated chitosan from the cuttlebone of Sepia kobiensis. The sulfated chitosan showed promising antibacterial and anticoagulant properties under semi-heterogeneous conditions.
NATURAL PRODUCT RESEARCH
(2022)
Review
Fisheries
Akshaya Radhakrishnan, Baskaralingam Vaseeharan, Pasiyappazham Ramasamy, Sivakamavalli Jeyachandran
Summary: The prevalence of infectious diseases in the aquaculture industry poses a threat to both fish immunity and human health. Unfortunately, existing oral vaccines have shown unsatisfactory efficacy. To overcome this, researchers are exploring different encapsulation methods to protect antigens and enhance the immune response.
AQUACULTURE INTERNATIONAL
(2023)
Editorial Material
Oncology
Kamala Kannan, Sivaperumal Pitchiah, E. Dilipan, Pasiyappazham Ramasamy
Letter
Oncology
D. J. Mukesh Kumar, P. Ramasamy, S. Suresh Kumar, P. Sivagurunathan
Review
Biochemistry & Molecular Biology
Pasiyappazham Ramasamy, Sakshee Vijay Dubal, Sivakamavalli Jeyachandran, Sivaperumal Pitchiah, Kamala Kannan, Dilipan Elangovan, Thinesh Thangadurai, Sivagurunathan Paramasivam, Joseph Selvin
Summary: Microbially influenced corrosion (MIC) of metals is a significant industrial problem with annual economic losses of 300-500 billion dollars worldwide. Eco-friendly coatings embedded with corrosion inhibitors developed from natural products, such as cephalopod chitosan, show potential for MIC prevention or control due to their unique biological properties. Chitosan acts as an antimicrobial coating substance by binding to the bacterial cell wall and disrupting its functions. It can also serve as a matrix for embedding other antimicrobial or anticorrosive substances to achieve synergistic effects. Field and laboratory experiments will be conducted to test this hypothesis and identify new eco-friendly MIC inhibitors.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2023)
Article
Food Science & Technology
Sivagurunathan Paramasivam, Balagayathri Ramkumar, Uma Chinnaiyan, Suman Polaki, Durga Rao Vegulada, Priyadharshini Ranganathan, Pasiyappazham Ramasamy
Summary: The study aimed to identify bioactive peptides from goat colostrum and analyze their physicochemical properties using in-silico analysis. The protein fractions in colostrum, transitional, and mature goat milk samples were quantified. Colostrum had the highest protein concentration compared to transitional and mature stages. Nine proteins were identified through analysis, including K casein, Alpha Lactalbumin, Ferritin, Calmodulin dependent protein kinase, Prolactin, Lactoferrin, Lactoperoxidase, Lysozyme, and Alpha-S2-casein. The findings of this study provide valuable insights for future research on the isolation and biological roles of bioactive peptides.
JOURNAL OF FOOD MEASUREMENT AND CHARACTERIZATION
(2023)
Article
Medicine, General & Internal
S. B. Shanmugam, Sivaperumal Pitchiah, Vasugi Suresh, Pasiyappazham Ramasamy
Summary: This study investigated the biosynthesis of copper nanoparticles from seaweed and their antioxidative potential. The seaweed-derived copper nanoparticles exhibited strong antioxidant activity, effectively scavenging free radicals.
CUREUS JOURNAL OF MEDICAL SCIENCE
(2023)
Letter
Clinical Neurology
B. Prakash, R. Krishnanand Pai, V. Chaitra, P. Ramasamy, N. Shuba
JOURNAL OF NEUROSCIENCES IN RURAL PRACTICE
(2017)
Article
Biochemistry & Molecular Biology
Wei-Han Hui, Yen-Lin Chen, Shu-Wei Chang
Summary: Crosslinking affects the mechanical behavior and tissue metabolism of collagen-based tissues. Aging and diabetes alter the crosslinking type and density, thus changing tissue properties. High-connectivity enzymatic crosslinking and advanced-glycation end-products result in uniform deformation under daily activity, while low-connectivity enzymatic crosslinking does not. High-connectivity model displays more sliding, while AGEs induce instability in structures near the binding sites.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Article
Biochemistry & Molecular Biology
Yao-Bin Ma, Xiao-Qiu Zhou, Wei-Dan Jiang, Pei Wu, Yang Liu, Shu-Wei Li, Ling Tang, Lu Zhang, Hai-Feng Mi, Lin Feng
Summary: Tea polyphenols (TPs) are an inexpensive feed additive that can protect the gill function of fish against Flavobacterium columnare (F. columnare) through various mechanisms, including suppression of oxidative stress, apoptosis, and inflammation.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Article
Biochemistry & Molecular Biology
Yan-Jia Guo, Jing-Ru Pang, Yu Zhang, Zhong-Rui Li, Xiao-Lin Zi, Hong-Min Liu, Ning Wang, Li-Juan Zhao, Ya Gao, Bo Wang, Piet Herdewijn, Cheng-Yun Jin, Ying Liu, Yi-Chao Zheng
Summary: This study identifies the conjugation of NEDD8 to LSD1 and its impact on GC cells, revealing the significance of LSD1 neddylation in GC.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Review
Biochemistry & Molecular Biology
Geum-Jae Jeong, Fazlurrahman Khan, Nazia Tabassum, Young-Mog Kim
Summary: Vibrio species are motile gram-negative bacteria commonly found in aquatic environments. They can adapt to environmental fluctuations and develop protective mechanisms against host immune systems. Different types of sigma and anti-sigma factors play important roles in regulating gene expression and virulence in Vibrio species.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Article
Biochemistry & Molecular Biology
Zahra Mohammadbagheri, Behrooz Movahedi, Shaghayegh Saeedi, Abbas Rahmati
Summary: In this study, a reusable biobased composite hydrogel was successfully synthesized and used for the removal of Tl(I) from aqueous solutions. The hydrogel exhibited high adsorption capacity and thermal stability, and the adsorption process was found to be thermodynamically spontaneous. The results demonstrated that the hydrogel can be reused multiple times without significant loss of its adsorption capacity.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Article
Biochemistry & Molecular Biology
Iqra Batool, Muhammad Imran, Ayesha Anwar, Farhan Ahmed Khan, Afrah E. Mohammed, Ashwag Shami, Hafiz Iqbal
Summary: Enzyme immobilization on ZnO/SnO2 and ZnO/SnO2/SA nanocomposites was studied, and the catalytic and biochemical characteristics of the immobilized enzyme were investigated. The results showed that ZnO/SnO2 and ZnO/SnO2/SA nanostructures are suitable carriers for enzyme immobilization.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Article
Biochemistry & Molecular Biology
Elias Mosaffa, Dhruvi Patel, Nasim Amiri Ramsheh, Rishikumar Indravadan Patel, Atanu Banerjee, Hossein Ghafuri
Summary: In this study, a unique 3D bead structure of adsorbent, composed of bacterial cellulose microfilaments reinforced chitosan adorned with melamine 2D plates, was synthesized for anionic dye removal. The adsorbent showed high specific surface area and abundant functional groups, resulting in exceptional adsorption capacity. The characteristics and optimal conditions of the adsorbent were assessed and analyzed.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Article
Biochemistry & Molecular Biology
Carolina Gismene, Jorge Enrique Hernandez Gonzalez, Marilia de Freitas Calmon, Andrey Fabricio Ziem Nascimento, Angela Rocio Nino Santisteban, Felipe Antunes Calil, Alana Della Torre da Silva, Paula Rahal, Rejane Maira Goes, Raghuvir Krishnaswamy Arni, Ricardo Barros Mariutti
Summary: Mammaliicoccus sciuri, a bacterium of clinical and veterinary relevance, expresses the virulence factor Exfoliative Toxin C (ExhC), which binds specifically to desmoglein-1 (Dsg1) and plays a role in tissue integrity. This study investigates the necrotic activity of ExhC and identifies a variant lacking necrotic potential but retaining enzymatic activity through mutagenesis experiments and crystal structure determination.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Article
Biochemistry & Molecular Biology
Bibhas K. Bhunia, Ashutosh Bandyopadhyay, Souradeep Dey, Biman B. Mandal
Summary: Intervertebral disc degeneration is a major cause of chronic low back pain and disability. Researchers have developed a bioactive silk-based hybrid hydrogel system functionalized with decellularized human Wharton's jelly extracellular matrix as bioactive cues. The hydrogels mimic the rheological and mechanical properties of the native nucleus pulposus tissue and support cell viability, proliferation, and tissue maturation.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Article
Biochemistry & Molecular Biology
Qun Zhang, Yonggan Yan, Zhao Li, Jing Du, Kai Zhang, Liguo Zhang, Ting Wang, Alberto Bianco, Shaohua Ge, Baojin Ma
Summary: A new crosslinking strategy has been devised to construct injectable sodium alginate hydrogels, which can be regulated for injectability and have great potential in biomedical applications.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Article
Biochemistry & Molecular Biology
Seong Eun Hong, Ji-Soo Lee, Hyeon Gyu Lee
Summary: The potential of multi-layer nanoemulsions for improving the cellular uptake, antioxidant activity, and in vitro bioaccessibility of alpha-tocopherol was examined. The results showed that the multi-layer nanoemulsions significantly enhanced the cellular uptake and antioxidant activity of alpha-tocopherol compared to free coumarin 6. Furthermore, the use of chitosan and dextran sulfate as wall materials in the multi-layer nanoemulsions led to even higher cellular uptake, in vitro bioaccessibility, and antioxidant activity of alpha-tocopherol.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Article
Biochemistry & Molecular Biology
Jingjing Yu, Yanhui Zhang, Ruoning Zhang, Yanxiang Gao, Like Mao
Summary: High internal phase emulsions (HIPEs) based on beeswax (BW) oleogels and octenyl succinic acid starch (OSA starch) were prepared by a simple one-step method. The results showed that oleogelation improved the stability and encapsulation capability of the HIPEs, which is significant for the development of novel healthy food.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Review
Biochemistry & Molecular Biology
Bi-Feng Yao, Xiu-Ju Luo, Jun Peng
Summary: The balanced and continuous fission and fusion of mitochondria, regulated by OPA1, are important for maintaining mitochondrial dynamics in cardiovascular disorders. Understanding the role of OPA1 in mitochondrial fusion can provide insights into the pathogenesis of cardiovascular diseases.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Review
Biochemistry & Molecular Biology
Gokul Paramasivam, Anandhavelu Sanmugam, Vishnu Vardhan Palem, Murugan Sevanan, Ananda Babu Sairam, Nachiappan Nachiappan, Buhyun Youn, Jung Sub Lee, Muthuchamy Nallal, Kang Hyun Park
Summary: Nanomaterials are being used to deliver therapeutic agents in living systems. Different nanotechnological applications such as immunosensors, immune assays, and drug delivery are being implemented using nanotechnology. Genomics plays a crucial role in selecting appropriate drugs for personalized cancer therapy. It helps in analyzing gene and protein expression, disease classification, and designing disease models. Delivering drugs to specific areas using nanoparticles is a challenging issue.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Article
Biochemistry & Molecular Biology
Jing Li, Wei Wang, Han Wu, Feng Peng, Hui Gao, Ying Guan
Summary: In this study, CMH-based CPF films were prepared and their thermal and barrier properties were successfully regulated. The tensile strength and water vapor barrier property of CPF films were significantly improved, making them promising for food packaging applications.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
