Bacteriophages for aquaculture disease control

The administration of phage therapy for aquaculture disease has been anticipated by the researchers over a decade as an effective and an alternative control mechanism, though the application of phages as a disease control agent in aquaculture projects various beneficial aspects, critical limitations, and negative influence on production. This present scenario made a pressure to review the possible disclosure of phage therapy with its critical boundaries and limiting influences towards the disease control management of aquaculture (fish, shrimps, lobsters, bivalve mollusks, etc.). The phage therapy has proven its efficacy as a biocontrol agent towards aquaculture disease, although the sustainability of the phage therapy needs further investigation on the following: commercial application, formulation of bacteriophage for layman usage, and development of protocol for various diseases with consistent results. The marginal space existing between the inventors and the end user must be fulfilled by the awareness program and the government policies. The administration of the phage therapy could be effective for long-term safety and negatively influence the development of multidrug-resistant bacteria pathogens in the future.