Hyperferritinemia and inflammation

Life-threatening NLRC4-associated hyperinflammation successfully treated with IL-18 inhibition

(2017) Scott W. Canna et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Secondary Hemophagocytic Lymphohistiocytosis

(2017) Zeliha Haytoglu et al.   JOURNAL OF PEDIATRIC HEMATOLOGY ONCOLOGY

A Systemic Inflammation Mortality Risk Assessment Contingency Table for Severe Sepsis*

(2017) Joseph A. Carcillo et al.   Pediatric Critical Care Medicine

Iron gene expression profile in atherogenic Mox macrophages

(2016) Liliana Marques et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

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(2016) Kate Kernan et al.   CRITICAL CARE MEDICINE

Interleukin-1 Receptor Blockade Is Associated With Reduced Mortality in Sepsis Patients With Features of Macrophage Activation Syndrome

(2016) Bita Shakoory et al.   CRITICAL CARE MEDICINE

Association of Multiple Biomarkers of Iron Metabolism and Type 2 Diabetes: The EPIC-InterAct Study

(2016) Clara Podmore et al.   DIABETES CARE

Ferritin levels and risk of heart failure-the Atherosclerosis Risk in Communities Study

(2016) Odilson M. Silvestre et al.   EUROPEAN JOURNAL OF HEART FAILURE

Red cell DAMPs and inflammation

(2016) Rafaela Mendonça et al.   INFLAMMATION RESEARCH

Genetic predisposition to hemophagocytic lymphohistiocytosis: Report on 500 patients from the Italian registry

(2016) Valentina Cetica et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

The Repair of Skeletal Muscle Requires Iron Recycling through Macrophage Ferroportin

(2016) Gianfranca Corna et al.   JOURNAL OF IMMUNOLOGY

Macrophages and iron trafficking at the birth and death of red cells

(2015) T. Korolnek et al.   BLOOD

A small-molecule inhibitor of the NLRP3 inflammasome for the treatment of inflammatory diseases

(2015) Rebecca C Coll et al.   NATURE MEDICINE

Evidence-based diagnosis and treatment of macrophage activation syndrome in systemic juvenile idiopathic arthritis

(2015) V. Boom et al.   Pediatric Rheumatology

TIMgenes: a family of cell surface phosphatidylserine receptors that regulate innate and adaptive immunity

(2015) Gordon J. Freeman et al.   IMMUNOLOGICAL REVIEWS

Distinct regulatory mechanisms of the human ferritin gene by hypoxia and hypoxia mimetic cobalt chloride at the transcriptional and post-transcriptional levels

(2014) Bo-Wen Huang et al.   CELLULAR SIGNALLING

sCD163 in AOSD: a biomarker for macrophage activation related to hyperferritinemia

(2014) S. Colafrancesco et al.   IMMUNOLOGIC RESEARCH

Hemophagocytic Lymphohistiocytosis

(2014) Jing Li et al.   MEDICINE

Performance of Current Guidelines for Diagnosis of Macrophage Activation Syndrome Complicating Systemic Juvenile Idiopathic Arthritis

(2014) Sergio Davì et al.   Arthritis & Rheumatology

Coupling Heme and Iron Metabolism via Ferritin H Chain

(2013) Raffaella Gozzelino et al.   ANTIOXIDANTS & REDOX SIGNALING

The Hyperferritinemic Syndrome: macrophage activation syndrome, Still’s disease, septic shock and catastrophic antiphospholipid syndrome

(2013) Cristina Rosário et al.   BMC Medicine

Suppression of immunoglobulin production in human peripheral blood mononuclear cells by monocytes via secretion of heavy-chain ferritin

(2013) Makiko Yamashita et al.   IMMUNOBIOLOGY

Interleukin-18 and IL-18 Binding Protein

(2013) Charles A. Dinarello et al.   Frontiers in Immunology

How I treat hemophagocytic lymphohistiocytosis

(2011) M. B. Jordan et al.   BLOOD

Hypomorphic mutations in PRF1, MUNC13-4, and STXBP2 are associated with adult-onset familial HLH

(2011) K. Zhang et al.   BLOOD

Repeated TLR9 stimulation results in macrophage activation syndrome–like disease in mice

(2011) Edward M. Behrens et al.   JOURNAL OF CLINICAL INVESTIGATION

Very high serum ferritin levels are associated with increased mortality and critical care in pediatric patients

(2011) Tellen D. Bennett et al.   Pediatric Critical Care Medicine

Serum ferritin is derived primarily from macrophages through a nonclassical secretory pathway

(2010) L. A. Cohen et al.   BLOOD

Type I Interferons Protect From Toll-Like Receptor 9–Associated Liver Injury and Regulate IL-1 Receptor Antagonist in Mice

(2010) Jan Petrasek et al.   GASTROENTEROLOGY

Polarization dictates iron handling by inflammatory and alternatively activated macrophages

(2010) G. Corna et al.   HAEMATOLOGICA

Macrophage activation syndrome: Serological markers and treatment with anti-thymocyte globulin

(2009) Andreea Coca et al.   CLINICAL IMMUNOLOGY

Early alterations of red blood cell rheology in critically ill patients*

(2009) Giulia Reggiori et al.   CRITICAL CARE MEDICINE

Differential regulation of iron homeostasis during human macrophage polarized activation

(2009) Stefania Recalcati et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Glyburide inhibits the Cryopyrin/Nalp3 inflammasome

(2009) Mohamed Lamkanfi et al.   JOURNAL OF CELL BIOLOGY

Drug-Induced Hypersensitivity Syndrome

(2009) Mona Ben m'rad et al.   MEDICINE

Secondary hemophagocytic lymphohistiocytosis and severe sepsis/systemic inflammatory response syndrome/multiorgan dysfunction syndrome/macrophage activation syndrome share common intermediate phenotypes on a spectrum of inflammation

(2009) Leticia Castillo et al.   Pediatric Critical Care Medicine

Ferritin Expression in Rat Hepatocytes and Kupffer Cells after Lead Nitrate Treatment

(2009) Yang Fan et al.   TOXICOLOGIC PATHOLOGY

Macrophage activation syndrome in rheumatic disease: What is the role of the antigen presenting cell?

(2008) Edward M. Behrens   AUTOIMMUNITY REVIEWS

Adult-onset Still disease

(2008) Bruno Fautrel   BEST PRACTICE & RESEARCH IN CLINICAL RHEUMATOLOGY

Cell-autonomous and systemic context-dependent functions of iron regulatory protein 2 in mammalian iron metabolism

(2008) D. Ferring-Appel et al.   BLOOD

Early diagnostic and prognostic significance of a specific Th1/Th2 cytokine pattern in children with haemophagocytic syndrome

(2008) Yongmin Tang et al.   BRITISH JOURNAL OF HAEMATOLOGY

Ferritin functions as a proinflammatory cytokine via iron-independent protein kinase C zeta/nuclear factor kappaB-regulated signaling in rat hepatic stellate cells

(2008) Richard G. Ruddell et al.   HEPATOLOGY

Effects of the Aspergillus fumigatus siderophore systems on the regulation of macrophage immune effector pathways and iron homeostasis

(2008) M. Seifert et al.   IMMUNOBIOLOGY

New functions for an iron storage protein: The role of ferritin in immunity and autoimmunity

(2008) Stefania Recalcati et al.   JOURNAL OF AUTOIMMUNITY

The inflammasome recognizes cytosolic microbial and host DNA and triggers an innate immune response

(2008) Daniel A. Muruve et al.   NATURE

Macrophages function as a ferritin iron source for cultured human erythroid precursors

(2007) Moshe J. Leimberg et al.   JOURNAL OF CELLULAR BIOCHEMISTRY