标题
The Complex Type 2 Endotype in Allergy and Asthma: From Laboratory to Bedside
作者
关键词
Allergy, Phenotype, Endotype, Th2 inflammation, Asthma, Rhinitis
出版物
CURRENT ALLERGY AND ASTHMA REPORTS
Volume 15, Issue 6, Pages -
出版商
Springer Nature
发表日期
2015-07-03
DOI
10.1007/s11882-015-0529-x
参考文献
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注意:仅列出部分参考文献,下载原文获取全部文献信息。- Heightened response of eosinophilic asthmatic patients to the CRTH2 antagonist OC000459
- (2014) R. Pettipher et al. ALLERGY
- Differences in Initial Immunoprofiles between Recurrent and Nonrecurrent Chronic Rhinosinusitis with Nasal Polyps
- (2014) Thibaut Van Zele et al. American Journal of Rhinology & Allergy
- High blood eosinophil count is associated with more frequent asthma attacks in asthma patients
- (2014) Trung N. Tran et al. ANNALS OF ALLERGY ASTHMA & IMMUNOLOGY
- Comparative Analysis of Human Epidermal and Peripheral Blood γδ T Cell Cytokine Profiles
- (2014) Kwangmi Kim et al. Annals of Dermatology
- Immunological and molecular targets of atopic dermatitis treatment
- (2014) A. Wollenberg et al. BRITISH JOURNAL OF DERMATOLOGY
- Re-defining the unique roles for eosinophils in allergic respiratory inflammation
- (2014) E. A. Jacobsen et al. CLINICAL AND EXPERIMENTAL ALLERGY
- Molecular Biology of Atopic Dermatitis
- (2014) Zhanglei Mu et al. CLINICAL REVIEWS IN ALLERGY & IMMUNOLOGY
- Interleukin-17 cytokine signalling in patients with asthma
- (2014) A. Linden et al. EUROPEAN RESPIRATORY JOURNAL
- Group 2 Innate Lymphoid Cells Are Critical for the Initiation of Adaptive T Helper 2 Cell-Mediated Allergic Lung Inflammation
- (2014) Timotheus Y.F. Halim et al. IMMUNITY
- Innate immunity in the lung regulates the development of asthma
- (2014) Rosemarie H. DeKruyff et al. IMMUNOLOGICAL REVIEWS
- Lung function decline and variable airway inflammatory pattern: Longitudinal analysis of severe asthma
- (2014) Christopher Newby et al. JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY
- Mechanisms of allergen-specific immunotherapy: Multiple suppressor factors at work in immune tolerance to allergens
- (2014) Mübeccel Akdis et al. JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY
- Allergen challenge in allergic rhinitis rapidly induces increased peripheral blood type 2 innate lymphoid cells that express CD84
- (2014) Taylor A. Doherty et al. JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY
- Sputum gene expression signature of 6 biomarkers discriminates asthma inflammatory phenotypes
- (2014) Katherine J. Baines et al. JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY
- Group 2 innate lymphoid cells facilitate sensitization to local, but not systemic, TH2-inducing allergen exposures
- (2014) Matthew J. Gold et al. JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY
- A thymic stromal lymphopoietin–responsive dendritic cell subset mediates allergic responses in the upper airway mucosa
- (2014) Guro R. Melum et al. JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY
- Dissecting childhood asthma with nasal transcriptomics distinguishes subphenotypes of disease
- (2014) Alex Poole et al. JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY
- Prostaglandin D2 activates group 2 innate lymphoid cells through chemoattractant receptor-homologous molecule expressed on TH2 cells
- (2014) Luzheng Xue et al. JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY
- Composition of Innate Lymphoid Cell Subsets in the Human Skin: Enrichment of NCR + ILC3 in Lesional Skin and Blood of Psoriasis Patients
- (2014) Marcel B.M. Teunissen et al. JOURNAL OF INVESTIGATIVE DERMATOLOGY
- TSLP Induces Mast Cell Development and Aggravates Allergic Reactions through the Activation of MDM2 and STAT6
- (2014) Na-Ra Han et al. JOURNAL OF INVESTIGATIVE DERMATOLOGY
- Effects of an Anti-TSLP Antibody on Allergen-Induced Asthmatic Responses
- (2014) Gail M. Gauvreau et al. NEW ENGLAND JOURNAL OF MEDICINE
- Salivary Inflammatory Mediator Profiling and Correlation to Clinical Disease Markers in Asthma
- (2014) Frédéric F. Little et al. PLoS One
- Factors Contributing to an Accelerated Decline in Pulmonary Function in Asthma
- (2014) Yoshihiro Kanemitsu et al. ALLERGOLOGY INTERNATIONAL
- Myeloid dendritic cells type 2 in allergic asthma
- (2013) B. Dua et al. ALLERGY
- Elevated Sputum Interleukin-5 and Submucosal Eosinophilia in Obese Individuals with Severe Asthma
- (2013) Dhananjay Desai et al. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
- Exploring the Effects of Omalizumab in Allergic Asthma
- (2013) Nicola A. Hanania et al. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
- IL-33–Responsive Innate Lymphoid Cells Are an Important Source of IL-13 in Chronic Rhinosinusitis with Nasal Polyps
- (2013) Joanne L. Shaw et al. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
- Predicting steroid responsiveness in patients with asthma using exhaled breath profiling
- (2013) M. P. van der Schee et al. CLINICAL AND EXPERIMENTAL ALLERGY
- From phenotypes to endotypes to asthma treatment
- (2013) Ioana O. Agache Current Opinion in Allergy and Clinical Immunology
- Prominent role of IFN-γ in patients with aspirin-exacerbated respiratory disease
- (2013) John W. Steinke et al. JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY
- Prostaglandin D2 pathway upregulation: Relation to asthma severity, control, and TH2 inflammation
- (2013) Merritt L. Fajt et al. JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY
- Exhaled nitric oxide levels and blood eosinophil counts independently associate with wheeze and asthma events in National Health and Nutrition Examination Survey subjects
- (2013) Andrei Malinovschi et al. JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY
- Thymic stromal lymphopoietin activity is increased in nasal polyps of patients with chronic rhinosinusitis
- (2013) Deepti R. Nagarkar et al. JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY
- Endotypes and phenotypes of chronic rhinosinusitis: A PRACTALL document of the European Academy of Allergy and Clinical Immunology and the American Academy of Allergy, Asthma & Immunology
- (2013) Cezmi A. Akdis et al. JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY
- Measures of gene expression in sputum cells can identify TH2-high and TH2-low subtypes of asthma
- (2013) Michael C. Peters et al. JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY
- Thymic stromal lymphopoietin induces corticosteroid resistance in natural helper cells during airway inflammation
- (2013) Hiroki Kabata et al. Nature Communications
- Untangling asthma phenotypes and endotypes
- (2012) I. Agache et al. ALLERGY
- Asthmatic Granulomatosis
- (2012) Sally E. Wenzel et al. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
- An Association betweenl-Arginine/Asymmetric Dimethyl Arginine Balance, Obesity, and the Age of Asthma Onset Phenotype
- (2012) Fernando Holguin et al. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
- Type 2 innate lymphoid cells: new players in asthma and allergy
- (2012) Seth T Scanlon et al. CURRENT OPINION IN IMMUNOLOGY
- Defective epithelial barrier in chronic rhinosinusitis: The regulation of tight junctions by IFN-γ and IL-4
- (2012) Michael B. Soyka et al. JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY
- Mechanisms of IFN-γ–induced apoptosis of human skin keratinocytes in patients with atopic dermatitis
- (2012) Ana Rebane et al. JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY
- Periostin is a systemic biomarker of eosinophilic airway inflammation in asthmatic patients
- (2012) Guiquan Jia et al. JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY
- Mepolizumab for severe eosinophilic asthma (DREAM): a multicentre, double-blind, placebo-controlled trial
- (2012) Ian D Pavord et al. LANCET
- Therapies for allergic inflammation: refining strategies to induce tolerance
- (2012) Cezmi A Akdis NATURE MEDICINE
- Innate and adaptive immune responses in asthma
- (2012) Stephen T Holgate NATURE MEDICINE
- The role of IL-33 and its receptor ST2 in human nasal epithelium with allergic rhinitis
- (2011) R. Kamekura et al. CLINICAL AND EXPERIMENTAL ALLERGY
- A randomized, double-blind, placebo-controlled study of the CRTH2 antagonist OC000459 in moderate persistent asthma
- (2011) N. Barnes et al. CLINICAL AND EXPERIMENTAL ALLERGY
- Persistent High FeNO Phenotype in Asthma
- (2011) I.O. Agache et al. JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY
- Fluctuation phenotyping based on daily fraction of exhaled nitric oxide values in asthmatic children
- (2011) Georgette Stern et al. JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY
- Asthma endotypes: A new approach to classification of disease entities within the asthma syndrome
- (2011) Jan Lötvall et al. JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY
- Increased expression of immunoreactive thymic stromal lymphopoietin in patients with severe asthma
- (2011) Aarti Shikotra et al. JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY
- Innate lymphoid cells responding to IL-33 mediate airway hyperreactivity independently of adaptive immunity
- (2011) Hye Young Kim et al. JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY
- Human IL-25- and IL-33-responsive type 2 innate lymphoid cells are defined by expression of CRTH2 and CD161
- (2011) Jenny M Mjösberg et al. NATURE IMMUNOLOGY
- Lebrikizumab Treatment in Adults with Asthma
- (2011) Jonathan Corren et al. NEW ENGLAND JOURNAL OF MEDICINE
- Accumulation of intraepithelial mast cells with a unique protease phenotype in TH2-high asthma
- (2010) Ryan H. Dougherty et al. JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY
- Increased serum IL-17 is an independent risk factor for severe asthma
- (2010) Ioana Agache et al. RESPIRATORY MEDICINE
- T-helper Type 2–driven Inflammation Defines Major Subphenotypes of Asthma
- (2009) Prescott G. Woodruff et al. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
- Administration of IL-33 induces airway hyperresponsiveness and goblet cell hyperplasia in the lungs in the absence of adaptive immune system
- (2008) Y. Kondo et al. INTERNATIONAL IMMUNOLOGY
- CD34+ hemopoietic progenitor cells are potent effectors of allergic inflammation
- (2008) Zoulfia Allakhverdi et al. JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY
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