Equivalent missense variant in the FOXP2 and FOXP1 transcription factors causes distinct neurodevelopmental disorders

Whole-exome sequencing in the molecular diagnosis of individuals with congenital anomalies of the kidney and urinary tract and identification of a new causative gene

(2016) Mir Reza Bekheirnia et al.   GENETICS IN MEDICINE

FOXP2variants in 14 individuals with developmental speech and language disorders broaden the mutational and clinical spectrum

(2016) Miriam S Reuter et al.   JOURNAL OF MEDICAL GENETICS

Functional characterization of rare FOXP2 variants in neurodevelopmental disorder

(2016) Sara B. Estruch et al.   Journal of Neurodevelopmental Disorders

A Foxp2 Mutation Implicated in Human Speech Deficits Alters Sequencing of Ultrasonic Vocalizations in Adult Male Mice

(2016) Jonathan Chabout et al.   Frontiers in Behavioral Neuroscience

The language-related transcription factor FOXP2 is post-translationally modified with small ubiquitin-like modifiers

(2016) Sara B. Estruch et al.   Scientific Reports

Dynamic Expression Patterns of Progenitor and Pyramidal Neuron Layer Markers in the Developing Human Hippocampus

(2015) Sara Cipriani et al.   CEREBRAL CORTEX

A de novo FOXP1 variant in a patient with autism, intellectual disability and severe speech and language impairment

(2015) Reymundo Lozano et al.   EUROPEAN JOURNAL OF HUMAN GENETICS

FoxP1 orchestration of ASD-relevant signaling pathways in the striatum

(2015) Daniel J. Araujo et al.   GENES & DEVELOPMENT

Identification and functional characterization ofde novo FOXP1variants provides novel insights into the etiology of neurodevelopmental disorder

(2015) Elliot Sollis et al.   HUMAN MOLECULAR GENETICS

A case of autism spectrum disorder arising from a de novo missense mutation in POGZ

(2015) Ryoko Fukai et al.   JOURNAL OF HUMAN GENETICS

Clinical whole exome sequencing in child neurology practice

(2014) Siddharth Srivastava et al.   ANNALS OF NEUROLOGY

What can mice tell us about Foxp2 function?

(2014) Catherine A French et al.   CURRENT OPINION IN NEUROBIOLOGY

Transcriptional Regulation by FOXP1, FOXP2, and FOXP4 Dimerization

(2014) Cora Sin et al.   JOURNAL OF MOLECULAR NEUROSCIENCE

Brain-specific Foxp1 deletion impairs neuronal development and causes autistic-like behaviour

(2014) C Bacon et al.   MOLECULAR PSYCHIATRY

De novo TBR1 mutations in sporadic autism disrupt protein functions

(2014) Pelagia Deriziotis et al.   Nature Communications

Small intragenic deletion in FOXP2 associated with childhood apraxia of speech and dysarthria

(2013) Samantha J Turner et al.   AMERICAN JOURNAL OF MEDICAL GENETICS PART A

FOXP1mutations cause intellectual disability and a recognizable phenotype

(2013) Anna K. Le Fevre et al.   AMERICAN JOURNAL OF MEDICAL GENETICS PART A

NovelFOXF1Mutations in Sporadic and Familial Cases of Alveolar Capillary Dysplasia with Misaligned Pulmonary Veins Imply a Role for its DNA Binding Domain

(2013) Partha Sen et al.   HUMAN MUTATION

Novel candidate genes and regions for childhood apraxia of speech identified by array comparative genomic hybridization

(2012) Jennifer J.S. Laffin et al.   GENETICS IN MEDICINE

An Alternative Splicing Switch Regulates Embryonic Stem Cell Pluripotency and Reprogramming

(2011) Mathieu Gabut et al.   CELL

An aetiological Foxp2 mutation causes aberrant striatal activity and alters plasticity during skill learning

(2011) C A French et al.   MOLECULAR PSYCHIATRY

Exome sequencing in sporadic autism spectrum disorders identifies severe de novo mutations

(2011) Brian J O'Roak et al.   NATURE GENETICS

De Novo Mutations in FOXP1 in Cases with Intellectual Disability, Autism, and Language Impairment

(2010) Fadi F. Hamdan et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Chiari I malformation, delayed gross motor skills, severe speech delay and epileptiform discharges in a child with FOXP1 haploinsufficiency

(2010) Christopher W Carr et al.   EUROPEAN JOURNAL OF HUMAN GENETICS

The Genome Analysis Toolkit: A MapReduce framework for analyzing next-generation DNA sequencing data

(2010) A. McKenna et al.   GENOME RESEARCH

Molecular networks implicated in speech-related disorders: FOXP2 regulates the SRPX2/uPAR complex

(2010) Patrice Roll et al.   HUMAN MOLECULAR GENETICS

A method and server for predicting damaging missense mutations

(2010) Ivan A Adzhubei et al.   NATURE METHODS

Fast and accurate short read alignment with Burrows-Wheeler transform

(2009) H. Li et al.   BIOINFORMATICS

A 785kb deletion of 3p14.1p13, including the FOXP1 gene, associated with speech delay, contractures, hypertonia and blepharophimosis

(2009) Mitchel J. Pariani et al.   European Journal of Medical Genetics

The forkhead transcription factors, Foxp1 and Foxp2, identify different subpopulations of projection neurons in the mouse cerebral cortex

(2009) T. Hisaoka et al.   NEUROSCIENCE

Impaired Synaptic Plasticity and Motor Learning in Mice with a Point Mutation Implicated in Human Speech Deficits

(2008) Matthias Groszer et al.   CURRENT BIOLOGY

Identification of 34 novel and 56 knownFOXL2mutations in patients with blepharophimosis syndrome

(2008) Diane Beysen et al.   HUMAN MUTATION

A Functional Genetic Link between Distinct Developmental Language Disorders

(2008) Sonja C. Vernes et al.   NEW ENGLAND JOURNAL OF MEDICINE