Functional characterization of rare FOXP2 variants in neurodevelopmental disorder

FOXP2variants in 14 individuals with developmental speech and language disorders broaden the mutational and clinical spectrum

(2016) Miriam S Reuter et al.   JOURNAL OF MEDICAL GENETICS

The language-related transcription factor FOXP2 is post-translationally modified with small ubiquitin-like modifiers

(2016) Sara B. Estruch et al.   Scientific Reports

Understanding Language from a Genomic Perspective

(2015) Sarah A. Graham et al.   Annual Review of Genetics

Identification and functional characterization ofde novo FOXP1variants provides novel insights into the etiology of neurodevelopmental disorder

(2015) Elliot Sollis et al.   HUMAN MOLECULAR GENETICS

The Key Regulator for Language and Speech Development, FOXP2, is a Novel Substrate for SUMOylation

(2015) Leslie J. Meredith et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Proteomic analyses reveal distinct chromatin-associated and soluble transcription factor complexes

(2015) X. Li et al.   Molecular Systems Biology

Contactin-associated protein-like 2 expression in SH-SY5Y cells is upregulated by a FOXP2 mutant with a shortened poly-glutamine tract

(2015) YUNJING ZHAO et al.   Molecular Medicine Reports

A Proteome-Scale Map of the Human Interactome Network

(2014) Thomas Rolland et al.   CELL

A Genotype-First Approach to Defining the Subtypes of a Complex Disease

(2014) Holly A. Stessman et al.   CELL

Mammalian-Specific Sequences in Pou3f2 Contribute to Maternal Behavior

(2014) Makoto Nasu et al.   Genome Biology and Evolution

Humanized Foxp2 accelerates learning by enhancing transitions from declarative to procedural performance

(2014) Christiane Schreiweis et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Structure-function analysis of mouse Sry reveals dual essential roles of the C-terminal polyglutamine tract in sex determination

(2014) L. Zhao et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

De novo TBR1 mutations in sporadic autism disrupt protein functions

(2014) Pelagia Deriziotis et al.   Nature Communications

Protein interaction network of alternatively spliced isoforms from brain links genetic risk factors for autism

(2014) Roser Corominas et al.   Nature Communications

Investigating Protein-protein Interactions in Live Cells Using Bioluminescence Resonance Energy Transfer

(2014) Pelagia Deriziotis et al.   Jove-Journal of Visualized Experiments

Small intragenic deletion in FOXP2 associated with childhood apraxia of speech and dysarthria

(2013) Samantha J Turner et al.   AMERICAN JOURNAL OF MEDICAL GENETICS PART A

NovelFOXF1Mutations in Sporadic and Familial Cases of Alveolar Capillary Dysplasia with Misaligned Pulmonary Veins Imply a Role for its DNA Binding Domain

(2013) Partha Sen et al.   HUMAN MUTATION

Sequencing of five left–right cerebral asymmetry genes in a cohort of schizophrenia and schizotypal disorder patients from Russia

(2013) Anastasia Levchenko et al.   PSYCHIATRIC GENETICS

Novel candidate genes and regions for childhood apraxia of speech identified by array comparative genomic hybridization

(2012) Jennifer J.S. Laffin et al.   GENETICS IN MEDICINE

The distinct and overlapping phenotypic spectra of FOXP1 and FOXP2 in cognitive disorders

(2012) Claire Bacon et al.   HUMAN GENETICS

The immunogenetics of immune dysregulation, polyendocrinopathy, enteropathy, X linked (IPEX) syndrome

(2012) Eva d'Hennezel et al.   JOURNAL OF MEDICAL GENETICS

FOXP2 and the role of cortico-basal ganglia circuits in speech and language evolution

(2011) Wolfgang Enard   CURRENT OPINION IN NEUROBIOLOGY

Protein Interactome Reveals Converging Molecular Pathways Among Autism Disorders

(2011) Y. Sakai et al.   Science Translational Medicine

FOXP2 gene and language impairment in schizophrenia: association and epigenetic studies

(2010) Amparo Tolosa et al.   BMC Medical Genetics

Molecular networks implicated in speech-related disorders: FOXP2 regulates the SRPX2/uPAR complex

(2010) Patrice Roll et al.   HUMAN MOLECULAR GENETICS

Humanized Foxp2 specifically affects cortico-basal ganglia circuits

(2010) S. Reimers-Kipping et al.   NEUROSCIENCE

Association between FOXP2 gene and speech sound disorder in Chinese population

(2010) Yunjing Zhao et al.   PSYCHIATRY AND CLINICAL NEUROSCIENCES

DECIPHER: Database of Chromosomal Imbalance and Phenotype in Humans Using Ensembl Resources

(2009) Helen V. Firth et al.   AMERICAN JOURNAL OF HUMAN GENETICS

A Humanized Version of Foxp2 Affects Cortico-Basal Ganglia Circuits in Mice

(2009) Wolfgang Enard et al.   CELL

Impaired Synaptic Plasticity and Motor Learning in Mice with a Point Mutation Implicated in Human Speech Deficits

(2008) Matthias Groszer et al.   CURRENT BIOLOGY

Missense mutations in the forkhead domain of FOXL2 lead to subcellular mislocalization, protein aggregation and impaired transactivation

(2008) Diane Beysen et al.   HUMAN MOLECULAR GENETICS

Expression ofFoxp4in the developing and adult rat forebrain

(2008) Kaoru Takahashi et al.   JOURNAL OF NEUROSCIENCE RESEARCH

Polymorphisms of coding trinucleotide repeats of homeogenes in neurodevelopmental psychiatric disorders

(2008) Fabrice Laroche et al.   PSYCHIATRIC GENETICS