A critical role of Hrd1 in the regulation of optineurin degradation and aggresome formation
出版年份 2017 全文链接
标题
A critical role of Hrd1 in the regulation of optineurin degradation and aggresome formation
作者
关键词
-
出版物
HUMAN MOLECULAR GENETICS
Volume 26, Issue 10, Pages 1877-1889
出版商
Oxford University Press (OUP)
发表日期
2017-03-09
DOI
10.1093/hmg/ddx096
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Optineurin: The autophagy connection
- (2016) Hongyu Ying et al. EXPERIMENTAL EYE RESEARCH
- Target Selection during Protein Quality Control
- (2016) Sichen Shao et al. TRENDS IN BIOCHEMICAL SCIENCES
- Cellular Functions of Optineurin in Health and Disease
- (2016) Karolina Slowicka et al. TRENDS IN IMMUNOLOGY
- Structural insights into the interaction and disease mechanism of neurodegenerative disease-associated optineurin and TBK1 proteins
- (2016) Faxiang Li et al. Nature Communications
- Whole-genome sequencing reveals important role for TBK1 and OPTN mutations in frontotemporal lobar degeneration without motor neuron disease
- (2015) Cyril Pottier et al. ACTA NEUROPATHOLOGICA
- Neuronal Aggregates: Formation, Clearance, and Spreading
- (2015) Junghyun Lim et al. DEVELOPMENTAL CELL
- TDP-43 loss of function increases TFEB activity and blocks autophagosome-lysosome fusion
- (2015) Q. Xia et al. EMBO JOURNAL
- TBK1 controls autophagosomal engulfment of polyubiquitinated mitochondria through p62/SQSTM1 phosphorylation
- (2015) Gen Matsumoto et al. HUMAN MOLECULAR GENETICS
- Defects in optineurin- and myosin VI-mediated cellular trafficking in amyotrophic lateral sclerosis
- (2015) Vinod Sundaramoorthy et al. HUMAN MOLECULAR GENETICS
- Nucleolar stress and impaired stress granule formation contribute to C9orf72 RAN translation-induced cytotoxicity
- (2015) Zhouteng Tao et al. HUMAN MOLECULAR GENETICS
- Autophagy receptor defects and ALS-FTLD
- (2015) Veronika Majcher et al. MOLECULAR AND CELLULAR NEUROSCIENCE
- The ubiquitin kinase PINK1 recruits autophagy receptors to induce mitophagy
- (2015) Michael Lazarou et al. NATURE
- Haploinsufficiency of TBK1 causes familial ALS and fronto-temporal dementia
- (2015) Axel Freischmidt et al. NATURE NEUROSCIENCE
- Ubiquitylation of Autophagy Receptor Optineurin by HACE1 Activates Selective Autophagy for Tumor Suppression
- (2014) Zhengzhao Liu et al. CANCER CELL
- Optineurin is an autophagy receptor for damaged mitochondria in parkin-mediated mitophagy that is disrupted by an ALS-linked mutation
- (2014) Yvette C. Wong et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Enhanced optineurin E50K–TBK1 interaction evokes protein insolubility and initiates familial primary open-angle glaucoma
- (2013) Yuriko Minegishi et al. HUMAN MOLECULAR GENETICS
- Amyotrophic lateral sclerosis: an update on recent genetic insights
- (2013) Yohei Iguchi et al. JOURNAL OF NEUROLOGY
- Endoplasmic Reticulum Stress and Parkinson’s Disease: The Role of HRD1 in Averting Apoptosis in Neurodegenerative Disease
- (2013) Tomohiro Omura et al. Oxidative Medicine and Cellular Longevity
- Optineurin and amyotrophic lateral sclerosis
- (2012) Hirofumi Maruyama et al. Geriatrics & Gerontology International
- Ataxin-3 Regulates Aggresome Formation of Copper-Zinc Superoxide Dismutase (SOD1) by Editing K63-linked Polyubiquitin Chains
- (2012) Hongfeng Wang et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Optineurin mediates a negative regulation of Rab8 by the GTPase-activating protein TBC1D17
- (2012) V. Vaibhava et al. JOURNAL OF CELL SCIENCE
- Ubiquitin-independent function of optineurin in autophagic clearance of protein aggregates
- (2012) J. Korac et al. JOURNAL OF CELL SCIENCE
- The Mammalian Endoplasmic Reticulum-Associated Degradation System
- (2012) J. A. Olzmann et al. Cold Spring Harbor Perspectives in Biology
- The Endoplasmic Reticulum (ER)-associated Degradation System Regulates Aggregation and Degradation of Mutant Neuroserpin
- (2011) Zheng Ying et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Optineurin in neurodegenerative diseases
- (2011) Tenshi Osawa et al. NEUROPATHOLOGY
- Phosphorylation of the Autophagy Receptor Optineurin Restricts Salmonella Growth
- (2011) P. Wild et al. SCIENCE
- Overexpression of optineurin E50K disrupts Rab8 interaction and leads to a progressive retinal degeneration in mice
- (2010) Zai-Long Chi et al. HUMAN MOLECULAR GENETICS
- Loss of HRD1-Mediated Protein Degradation Causes Amyloid Precursor Protein Accumulation and Amyloid- Generation
- (2010) M. Kaneko et al. JOURNAL OF NEUROSCIENCE
- Mutations of optineurin in amyotrophic lateral sclerosis
- (2010) Hirofumi Maruyama et al. NATURE
- Genome-wide association study identifies variants at CSF1, OPTN and TNFRSF11A as genetic risk factors for Paget's disease of bone
- (2010) Omar M E Albagha et al. NATURE GENETICS
- Ubiquitin-like protein conjugation and the ubiquitin–proteasome system as drug targets
- (2010) Lynn Bedford et al. NATURE REVIEWS DRUG DISCOVERY
- Analysis of optineurin in frontotemporal lobar degeneration
- (2010) Sara Rollinson et al. NEUROBIOLOGY OF AGING
- Gp78, an ER associated E3, promotes SOD1 and ataxin-3 degradation
- (2009) Zheng Ying et al. HUMAN MOLECULAR GENETICS
- Degradation of Sterol Regulatory Element-binding Protein Precursor Requires the Endoplasmic Reticulum-associated Degradation Components Ubc7 and Hrd1 in Fission Yeast
- (2009) Bridget T. Hughes et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Mutant Huntingtin Impairs Post-Golgi Trafficking to Lysosomes by Delocalizing Optineurin/Rab8 Complex from the Golgi Apparatus
- (2009) Daniel del Toro et al. MOLECULAR BIOLOGY OF THE CELL
- α-Synuclein is part of a diverse and highly conserved interaction network that includes PARK9 and manganese toxicity
- (2009) Aaron D Gitler et al. NATURE GENETICS
- A Critical Role for CHIP in the Aggresome Pathway
- (2008) Y. Sha et al. MOLECULAR AND CELLULAR BIOLOGY
- Ubiquitin, the proteasome and protein degradation in neuronal function and dysfunction
- (2008) Hwan-Ching Tai et al. NATURE REVIEWS NEUROSCIENCE
Create your own webinar
Interested in hosting your own webinar? Check the schedule and propose your idea to the Peeref Content Team.
Create NowAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started