The biological impact of blood pressure-associated genetic variants in the natriuretic peptide receptor C gene on human vascular smooth muscle

Novel Blood Pressure Locus and Gene Discovery Using Genome-Wide Association Study and Expression Data Sets From Blood and the KidneyNovelty and Significance

(2017) Louise V. Wain et al.   HYPERTENSION

Genome-wide association analysis identifies novel blood pressure loci and offers biological insights into cardiovascular risk

(2017) Helen R Warren et al.   NATURE GENETICS

Trans-ancestry meta-analyses identify rare and common variants associated with blood pressure and hypertension

(2016) Praveen Surendran et al.   NATURE GENETICS

The genetics of blood pressure regulation and its target organs from association studies in 342,415 individuals

(2016) Georg B Ehret et al.   NATURE GENETICS

Defective Natriuretic Peptide Receptor Signaling in Skeletal Muscle Links Obesity to Type 2 Diabetes

(2015) Marine Coué et al.   DIABETES

Natriuretic Peptide Receptor-C Attenuates Hypertension in Spontaneously Hypertensive Rats

(2014) Yuan Li et al.   HYPERTENSION

Endothelial C-type natriuretic peptide maintains vascular homeostasis

(2014) Amie J. Moyes et al.   JOURNAL OF CLINICAL INVESTIGATION

Identifying multiple causative genes at a single GWAS locus

(2013) M. J. Flister et al.   GENOME RESEARCH

Genome-Wide Association Study Meta-Analysis Reveals Transethnic Replication of Mean Arterial and Pulse Pressure Loci

(2013) Tanika N. Kelly et al.   HYPERTENSION

Natriuretic Peptide Receptor-C Agonist Attenuates the Expression of Cell Cycle Proteins and Proliferation of Vascular Smooth Muscle Cells from Spontaneously Hypertensive Rats: Role of Gi Proteins and MAPkinase/PI3kinase Signaling

(2013) Jasmine El Andalousi et al.   PLoS One

Large-Scale Development of Cost-Effective Single-Nucleotide Polymorphism Marker Assays for Genetic Mapping in Pigeonpea and Comparative Mapping in Legumes

(2012) R. K. Saxena et al.   DNA RESEARCH

Using formaldehyde-assisted isolation of regulatory elements (FAIRE) to isolate active regulatory DNA

(2012) Jeremy M Simon et al.   Nature Protocols

Blood Pressure Loci Identified with a Gene-Centric Array

(2011) Toby Johnson et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Natriuretic peptide receptor-3 underpins the disparate regulation of endothelial and vascular smooth muscle cell proliferation by C-type natriuretic peptide

(2011) Rayomand S Khambata et al.   BRITISH JOURNAL OF PHARMACOLOGY

Genetic variants in novel pathways influence blood pressure and cardiovascular disease risk

(2011) Georg B. Ehret et al.   NATURE

Meta-analysis of genome-wide association studies identifies common variants associated with blood pressure variation in east Asians

(2011) Norihiro Kato et al.   NATURE GENETICS

Disease Risk Links to Gene Regulation

(2011) E. Pennisi   SCIENCE

Role of p47phox in regulating Cdc42GAP, vimentin, and contraction in smooth muscle cells

(2009) Qing-Fen Li et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Understanding the contribution of Guyton's large circulatory model to long-term control of arterial pressure

(2009) Jean-Pierre Montani et al.   EXPERIMENTAL PHYSIOLOGY

Potential etiologic and functional implications of genome-wide association loci for human diseases and traits

(2009) L. A. Hindorff et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA